toobs1234
toobs1234
@toobs
Topics: 0 / Replies: 31
Reply
RE: Dietary restriction of amino acids for Cancer therapy

@j this is especially true for those doing immunotherapy. I don't have the reference handy, but I read one study that found patients who had a "good" ...

11 months ago
Forum
Reply
RE: Dietary restriction of amino acids for Cancer therapy

@j this is especially true for those doing immunotherapy. I don't have the reference handy, but I read one study that found patients who had a "good" ...

11 months ago
Forum
Reply
RE: Innate Immune Training --- Anti-tumor Activity

From what I can tell, Immucura is selling snake oil. I asked them for more information about the antigens they were using to activate the dendritic ce...

11 months ago
Reply
RE: Is Curcumin the Answer to Future Chemotherapy Cocktail?

@cl812271 In my opinion, the best thing you can do is get expression testing done on your tumor biopsy and figure out what's really going on in you...

1 year ago
Reply
RE: Luteolin ... effects on MDMX and where to buy?

thanks!!! if someone else has an issue with MDMX (MDM4), which is common. Pay attention to the splicing variant you are expressing. In my case t...

1 year ago
Reply
RE: Curcumin - Celecoxib synergy

thanks for this I am starting on this combo (using Curqfen as the Curcumin source). I think I will be around 5uM of Celecoxib and 1uM of free Curcum...

1 year ago
Reply
RE: Luteolin ... effects on MDMX and where to buy?

There are chinese suppliers, but are they reliable? Anyone know about Vitamondo? but then getting it through customs ...

1 year ago
Reply
RE: Fasting as an anti-cancer strategy

I will just add to this that my psa dropped by 40% after two fasts of 48 hours (two weeks between tests). My blood sugar got down to 60 and I was taki...

1 year ago
Forum
Topic
Replies: 2
Views: 417
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

Hi Gge, Please take a look at the original paper I cited: It shows the impact of Diflunisal on lactate efflux not only alone, but in combinatio...

3 years ago
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

Hi gge, This is really helpful! That's now three human cases I know of. Two positive, one negative. Please share any details you can. Knowledge is k...

3 years ago
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

Hi gge, I'm separated from my computer right now, but when I get back I'll post some references that support the MCT1 inhibition effectiveness of d...

3 years ago
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

I think you may have missed the point of diflunisal+syro...you can't dose syro high enough orally to get effective MCT1 inhibition. You can, however, ...

3 years ago
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

@gge Hi gge, Take a look at figure 5C. That's the results of the in vivo experiment...only inhibition of growth. Unfortunately.

3 years ago
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

Great find. I hadn't seen that one. It's very useful to have another in vivo experiment, this time with actual data. Although it's disappointing that ...

3 years ago
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

This paper has a summary of the expression levels of MCT1 found in studies of different types of cancer. It was at least partially expressed in all st...

3 years ago
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

Hi GgE, I don't want to be negative. I just want to be realistic. There are soooo many research articles that show anti-cancer effects of drugs or n...

3 years ago
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

Well I spent a few days trying to find some kind of indication about the pharmacokinetics of Syrosingopine. I didn't find anything definitive, but wha...

3 years ago
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

@gge Interesting! When I first saw the patent numbers you are referring to, I noticed that they roughly corresponded with the practical range of hum...

3 years ago
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

@daniel Thanks so much Daniel! That's a perfect example of why this resource you've put together is so valuable. I'm 5 months into this journey ...

3 years ago
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

That was one of the parts of my post that I wanted to edit. It's unclear as written. The 50mg is already with the factor of 12 included! 7.5mg/kg/12*8...

3 years ago
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

unrelated: it would be really nice to be able to edit your posts to correct typos!

3 years ago
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

Diflunisal+Syrosingopine+Metformin The Syrosingopine/Metformin strategy is really interesting, but I have serious doubts about whether we can achiev...

3 years ago
Reply
RE: Synergy between mebendazole and methionine depletion (vegan diet)

"The mechanism of action likely involves both the methylation of tubulins and regulation of mitosis related gene by rMETase. S-adenosyl-L-methionine (...

3 years ago
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

Looking for ENO2 (gamma enolase) inhibitors, I only found SF2312, which is a recently discovered chemical never used in humans as far as I know. ENO2 ...

3 years ago
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

@haroldo-cazeao where are you located?

3 years ago
Reply
RE: Combo Metformin And Syrosingopine!!!! Looks Awesome!

@daniel I didn't notice 2-DG in your list of drugs for coronavirus, but it's been confirmed to work in vitro:/p> The authors attribute this to block...

3 years ago
Page 1 / 2