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Combination of metformin and statin inhibits cell proliferation, in TNBC
By Daniel, 1 day ago |
Breast cancer |
| Metformin Targets Cholesterol Biosynthesis Pathway, GM1 Lipid Raft Stabilization, EGFR Signaling and Proliferation in Triple Negative Breast Cancers | ||
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RE: Please help Thyroid cancer with BRAFV600E mutation
By Daniel, 1 day ago |
Thyroid cancer |
| @ravi-teja Hi Ravi, You are welcome. Not sure if Diclofenac can do similar job but this could be another MCT4 inhibitor Lipophilic statins such as Atorvastatin could be another option . But the conce... | ||
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RE: Please help Thyroid cancer with BRAFV600E mutation
By Ravi Teja, 1 day ago |
Thyroid cancer |
| @daniel Hello Daniel Thank you so much for the suggestion. It means a lot. I have been trying to fetch Syrosingopine locally in India but unable to find it in any medical outlet . Is there any other... | ||
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Intra-operative administration of ketorolac, is statistically significantly associated with a reduction of distant recurrences in Breast Cancer patients
By Daniel, 2 days ago |
Breast cancer |
| Potential Benefit of Intra-operative Administration of Ketorolac on Breast Cancer Recurrence According to the Patient's Body Mass Index. These results show that the intra-operative administration of k... | ||
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Combo Metformin and Diclofenac
By Daniel, 2 days ago |
Metabolic Inhibitors |
| Following the concept of combining glycolisis (fermentation) and mithocondria inhibitors to kill cancer, such as it was previously demonstrated with the syrosingopine + metformin and Vitamin C + Doxyc... | ||
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Most effective NSAID
By Shanti, 2 days ago |
Repurposed Drugs |
| Hi D and All, Any thoughts on best NSAIDs as part of an off-label cancer approach? Celecoxib, Diclofenac, Aspirin? Obviously, if there is research on an NSAID for a specific cancer/situation, you wo... | ||
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RE: Heat Destroys Cancer
By Shanti, 2 days ago |
Devices |
| @kp Hi KP, We purchased an infrared solo sauna from Sunlighten and initially used it as part of an "oxidative stress day" along with fasting, IVC, ozone and artemisinin. I do not know how effective i... | ||
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RE: Please help Thyroid cancer with BRAFV600E mutation
By Daniel, 2 days ago |
Thyroid cancer |
| @ravi-teja Dear Ravi, You are very welcome. It is best that first you try to find the required doses yourself. After that you let me know what daily dose you think is best and I will give you my feedb... | ||
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RE: Please help Thyroid cancer with BRAFV600E mutation
By Ravi Teja, 2 days ago |
Thyroid cancer |
| Hello Daniel, Thank you so much for taking time and helping with information. Request to kindly help me with below Once the course of these meds starts what is the duration of these meds to be taken ... | ||
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RE: A novel function of geranylgeraniol in regulating testosterone production
By Daniel, 2 days ago |
Prostate cancer |
| Indeed, Forskolin, a natural plant extract that is derived from geranylgeranyl pyrophosphate is used in the lab to increase levels of cyclic AMP by stimulation of adenylate cyclase in laboratory, whic... | ||
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A novel function of geranylgeraniol in regulating testosterone production
By Daniel, 2 days ago |
Prostate cancer |
| A recent study shows that Geranylgeraniol, a substance found in plants but also produced by the cells in the human body, via the mevalonate pathway, can regulate the steroidogenesis pathway and as a ... | ||
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Dose Escalation Trial of the Wee1 Inhibitor Adavosertib (AZD1775) in Combination With Gemcitabine and Radiation for Patients With Locally Advanced Pancreatic Cancer
By johan, 2 days ago |
Pancreatic cancer |
| "AZD1775 in combination with gemcitabine and radiation therapy was well tolerated at a dose that produced target engagement in a surrogate tissue. The overall survival is substantially higher than pri... | ||
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RE: Please help Thyroid cancer with BRAFV600E mutation
By Daniel, 2 days ago |
Thyroid cancer |
| Dear, 1. Disease-free survival and overall survival of patients with thyroid carcinoma were shown to be significantly decreased when glucose transporter 1 and tumoral monocarbonylate transporter 4 are... | ||
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RE: neuroendocrine ca
By Daniel, 3 days ago |
Chemotherapy & Others |
| @kp Hi, I would use a dewormer anyway. Fenbendazole is one option, Mebendazole is another option I would do cycles with antiparasites from time to time. If possible, I would use two at the same time.... | ||
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RE: Heat Destroys Cancer
By Daniel, 3 days ago |
Devices |
| @kp I have no specific opinion but studies suggest it helps: Biological effects and medical applications of infrared radiation Far infrared ray (FIR) therapy: An effective and oncological safe treatm... | ||
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