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Daniel Combination of metformin and statin inhibits cell proliferation, in TNBC  

By Daniel, 1 day ago

Breast cancer
  Metformin Targets Cholesterol Biosynthesis Pathway, GM1 Lipid Raft Stabilization, EGFR Signaling and Proliferation in Triple Negative Breast Cancers
Daniel RE: Please help Thyroid cancer with BRAFV600E mutation  

By Daniel, 1 day ago

Thyroid cancer
  @ravi-teja Hi Ravi, You are welcome. Not sure if Diclofenac can do similar job but this could be another MCT4 inhibitor Lipophilic statins such as Atorvastatin could be another option . But the conce...
Ravi Teja RE: Please help Thyroid cancer with BRAFV600E mutation  

By Ravi Teja, 1 day ago

Thyroid cancer
  @daniel Hello Daniel  Thank you so much for the suggestion. It means a lot.  I have been trying to fetch Syrosingopine locally in India but unable to find it in any medical outlet . Is there any other...
Daniel Intra-operative administration of ketorolac, is statistically significantly associated with a reduction of distant recurrences in Breast Cancer patients  

By Daniel, 2 days ago

Breast cancer
  Potential Benefit of Intra-operative Administration of Ketorolac on Breast Cancer Recurrence According to the Patient's Body Mass Index. These results show that the intra-operative administration of k...
Daniel Combo Metformin and Diclofenac  

By Daniel, 2 days ago

Metabolic Inhibitors
  Following the concept of combining glycolisis (fermentation) and mithocondria inhibitors to kill cancer, such as it was previously demonstrated with the syrosingopine + metformin and Vitamin C + Doxyc...
Shanti Most effective NSAID  

By Shanti, 2 days ago

Repurposed Drugs
  Hi D and All, Any thoughts on best NSAIDs as part of an off-label cancer approach?   Celecoxib, Diclofenac, Aspirin? Obviously, if there is research on an NSAID for a specific cancer/situation, you wo...
Shanti RE: Heat Destroys Cancer  

By Shanti, 2 days ago

Devices
  @kp Hi KP, We purchased an infrared solo sauna from Sunlighten and initially used it as part of an "oxidative stress day" along with fasting, IVC, ozone and artemisinin.  I do not know how effective i...
Daniel RE: Please help Thyroid cancer with BRAFV600E mutation  

By Daniel, 2 days ago

Thyroid cancer
  @ravi-teja Dear Ravi, You are very welcome. It is best that first you try to find the required doses yourself. After that you let me know what daily dose you think is best and I will give you my feedb...
Ravi Teja RE: Please help Thyroid cancer with BRAFV600E mutation  

By Ravi Teja, 2 days ago

Thyroid cancer
  Hello Daniel, Thank you so much for taking time and helping with information.  Request to kindly help me with below Once the course of these meds starts what is the duration of these meds to be taken ...
Daniel RE: A novel function of geranylgeraniol in regulating testosterone production  

By Daniel, 2 days ago

Prostate cancer
  Indeed, Forskolin, a natural plant extract that is derived from geranylgeranyl pyrophosphate is used in the lab to increase levels of cyclic AMP by stimulation of adenylate cyclase in laboratory, whic...
Daniel A novel function of geranylgeraniol in regulating testosterone production  

By Daniel, 2 days ago

Prostate cancer
  A recent study shows that Geranylgeraniol, a substance found in plants but also produced by the cells in the human body, via the mevalonate pathway, can regulate the steroidogenesis pathway and as a ...
johan Dose Escalation Trial of the Wee1 Inhibitor Adavosertib (AZD1775) in Combination With Gemcitabine and Radiation for Patients With Locally Advanced Pancreatic Cancer  

By johan, 2 days ago

Pancreatic cancer
  "AZD1775 in combination with gemcitabine and radiation therapy was well tolerated at a dose that produced target engagement in a surrogate tissue. The overall survival is substantially higher than pri...
Daniel RE: Please help Thyroid cancer with BRAFV600E mutation  

By Daniel, 2 days ago

Thyroid cancer
  Dear, 1. Disease-free survival and overall survival of patients with thyroid carcinoma were shown to be significantly decreased when glucose transporter 1 and tumoral monocarbonylate transporter 4 are...
Daniel RE: neuroendocrine ca  

By Daniel, 3 days ago

Chemotherapy & Others
  @kp Hi, I would use a dewormer anyway. Fenbendazole is one option, Mebendazole is another option I would do cycles with antiparasites from time to time. If possible, I would use two at the same time....
Daniel RE: Heat Destroys Cancer  

By Daniel, 3 days ago

Devices
  @kp I have no specific opinion but studies suggest it helps: Biological effects and medical applications of infrared radiation Far infrared ray (FIR) therapy: An effective and oncological safe treatm...
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