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johan RE: Apigenin to enhance chemotherapy  

By johan, 2 days ago

  @daniel could you check on the antispam setting of the forum, I just typed a response to @ram including a link to Pubmed and it didn't get thru. annoying! Please add PubMed to a list of no-spam URLs i...
RE: Apigenin to enhance chemotherapy  

By J Ramon, 3 days ago

  @j Hello Johan. I came across an interesting post by Daniel. He said: "Indeed, many of the natural compounds appear to be cell type-specific, concentration-dependent, and may vary in their action depe...
RE: Doxycycline, Metformin, and Chemo  

By J Ramon, 6 days ago

  @j Thank you!
johan RE: Doxycycline, Metformin, and Chemo  

By johan, 6 days ago

  meant to type "anticancer synergies"
johan RE: Doxycycline, Metformin, and Chemo  

By johan, 6 days ago

  @ram just recently I started looking into pancreatic cancer, from my specific perspective of anti-synergies I must add, but I'll expand my searches and take your information into account. I'll get bac...
RE: Doxycycline, Metformin, and Chemo  

By J Ramon, 6 days ago

  @j Thank you, Johan. Unfortunately, my mom's cancer is a rare form of cancer called pancreatic acinar cell carcinoma. There is not much in the way of research. She has decided to go with this chemothe...
johan RE: Doxycycline, Metformin, and Chemo  

By johan, 6 days ago

  @ram thanks! In a pro-oxidant strategy, you're pushing cancer cells beyond their capacity to deal with oxidative stress. In my view, chemotherapy already does a great job at this. If you disrupt or in...
Doxycycline, Metformin, and Chemo  

By J Ramon, 6 days ago

  @j Great blog and spreadsheet, Johan! I wanted to get your thoughts on the use of Doxycycline and Metformin during chemotherapy. In the article, "Shutting Down the Power House of Cancer," it says, "In...
johan RE: Apigenin to enhance chemotherapy  

By johan, 1 week ago

  @ram and since you are planning on using apigenin and luteolin note that there are possible synergistic effects among these molecules, for more info on anticancer synergies you might want to check out...
johan RE: Apigenin to enhance chemotherapy  

By johan, 1 week ago

  @ram studies have used varying doses, anticancer effects appear to start at relatively low doses albeit not likely achievable through diet. But yes same remark as with apigenin, with anticancer effect...
RE: Apigenin to enhance chemotherapy  

By J Ramon, 1 week ago

  @j Great. Thank you. Are Luteolin's chemo-enhancing properties also dosage dependent?
johan RE: Apigenin to enhance chemotherapy  

By johan, 1 week ago

  @ram half-life is short about 5 hours I believe so it's best to spread it out over the day e.g. morning, noon, evening
dipyridamole and chemo  

By J Ramon, 1 week ago

  Hello. Does anyone know if dipyridamole should be treated as a fermentation inhibitor and stopped three days before chemo and restarted on the day of chemo? Or, should it be taken continuously?
RE: Apigenin to enhance chemotherapy  

By J Ramon, 1 week ago

  @j Thank you. I was wondering: Does the research show to take the 1 gram/day of apigenin in a single dose or can it be something like 400mg 3x/day?
johan RE: Apigenin to enhance chemotherapy  

By johan, 1 week ago

  @ram 2 to 3 days generally is enough time, yes.
RE: Apigenin to enhance chemotherapy  

By J Ramon, 1 week ago

  @j Thank you. My mom will be given paclitaxel (60 mg/m²) or Abraxane, oxaliplatin (50 mg/m²), Leucovorin (20 mg/m², minimum dose of 40 mg), and 5-FU (425 mg/m²) each week for 12 weeks. She won't be ta...
johan RE: Apigenin to enhance chemotherapy  

By johan, 1 week ago

  @ram you need to check the supplements against each drug used in the cancer treatment. Some supplements can interfere with how much of the drug enters systemic circulation or how it's detoxified. Apig...
johan RE: Supplements and weekly low-dose metronomic chemo  

By johan, 1 week ago

  @ram Maybe a little there's no way to tell but natural products can reduce harm to normal cells e.g. curcumin reduces cytotoxicity of 5-FU ref Protecting the liver and kidneys from chemotherapy is ver...
Luteolin to enhance chemotherapy  

By J Ramon, 2 weeks ago

  Hello. Is Luteolin's chemo-enhancing properties dosage dependent? If so, can anyone tell me what that dosage is? Thank you.
Apigenin to enhance chemotherapy  

By J Ramon, 2 weeks ago

  Hello. Is apigenin's chemo-enhancing properties dosage dependent? If so, can anyone tell me what that dosage is? Thank you.
Supplements and weekly low-dose metronomic chemo  

By J Ramon, 2 weeks ago

  Hello. My mother will be starting low-dose chemo soon. The regiment includes paclitaxel (60 mg/m²) or Abraxane, oxaliplatin (50 mg/m²), Leucovorin (20 mg/m², minimum dose of 40 mg), and 5-FU (425 mg/m...
RE: Piperlongumine  

By J Ramon, 2 weeks ago

  Thank you, Johan, for responding to my question. The dose in the article you provided is 1.5 mg/kg/day. My mom weighs 63.5kg. So, theoretically speaking, she should take at least 95mg of Piperlongumin...
johan RE: Piperlongumine  

By johan, 2 weeks ago

  @ram I wouldn't worry about any antioxidant activity you might find in the scientific literature about PL, if any it's weak and will not produce any protumor effect. N-acetylcysteine (NAC) and glutath...
Piperlongumine  

By J Ramon, 2 weeks ago

  The dose for Piperlongumine (Long Pepper) is 3g/day in the article “Modulating the Yin and Yang Energy of Cells to Fight Cancer:Pro-Oxidant Strategy.” Does anyone know if Piperlongumine is an antioxid...

 

 

 

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