Statins and Cancer Dear Friends, I am currently on holiday, travelling and with little access to the computer, but recently I came across interesting information related to the use of Statins to fight cancer, and would like to share that with you as soon as possible. So I decided to allocate a day and consolidate
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Category: Cancer Types
The list below and the info for every type of cancer will be continuously updated.
Case Report Stage IV Pancreatic Cancer: Good News from Jess
During this summer, on August 10, 2018, Jess was informing us (here) regarding the fact that her dad, dealing with Pancreatic Cancer Stage IV, will start a similar treatment approach as that successfully used by Marcos, and shortly discussed on this website (here). Jess and I have exchanged a large amount of e-mails this year and
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Case Report: Hepatocellular Carcinoma (HCC) Successfully Managed with TACE
Dear Friends, Below is a case report I recently received from Stefan, a visitor of this website. The case report is related to his sister-in-law, a 74-years lady, who has successfully managed a Hepatocellular Carcinoma (HCC) with a transarterial chemoembolization (TACE) performed at a hospital in Romania, Cluj. My purpose in sharing this with you
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Prostate Cancer
This post is intended to be a part of the “Cancer Type” category, and represents a list of info including drugs and supplements that may be relevant when fighting prostate cancer. Note that these drugs and supplements must not represent the replacement of conventional therapies. Instead, they may be used in agreement with the medical
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Pancreatic cancer: Towards increasing treatment effectivness
Dear Visitors, below is a list of drugs recently shared with me by a reader of this website. It contains relevant information and consequently I decided to publish it as a specific article. I hope this will help: Currently the two most effective regimens in advanced pancreatic cancer are FOLFIRINOX (folinic acid, fluorouracil, irinotecan and oxaliplatin)
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Brain Cancer
Relevant drugs/supplements/protocols for brain cancer: cusp9 protocol (Ref.) Chlorimipramine, the keto diet and Boswellic Acid Noscapine inhibits tumor growth in TMZ-resistant gliomas http://www.ncbi.nlm.nih.gov/pubmed/21925789 Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas http://www.ncbi.nlm.nih.gov/pubmed/25542083 Chloroquine enhances temozolomide cytotoxicity in malignant gliomas by blocking autophagy http://www.ncbi.nlm.nih.gov/pubmed/25434381 Tetanus Vaccine Boosts Cancer Therapy http://www.nbcnews.com/health/cancer/tetanus-vaccine-boosts-cancer-therapy-n321596 Asparagine depletion potentiates
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Myeloma
Statin-Dipyridamole Statin-Dipyridamole combination for hematologic malignancies (and not only) New therapies are urgently needed for hematologic malignancies, especially in patients with relapsed acute myelogenous leukemia (AML) and multiple myeloma. We and others have previously shown that FDA-approved statins, which are used to control hypercholesterolemia and target the mevalonate pathway (MVA), can trigger tumor-selective apoptosis. Our
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Leukemia
I was shortly looking through potential solutions forLeukemia and here is a summary of my (limited) view on that so far: A major approach when trying to treat leukemia is to focus on Iron depletion (chelation). This can be done with Artemisin, Baicalein and Ciclopirox olamine or even Galium compounds. . Next to that, as
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Pancreatic Cancer
The list below will be continuously updated. Alpha-lipoic acid + low-dose naltrexone: Revisiting the ALA/N (alpha-lipoic acid/low-dose naltrexone) protocol for people with metastatic and nonmetastatic pancreatic cancer: a report of 3 new cases. http://www.ncbi.nlm.nih.gov/pubmed/20042414 Dipyridamole Chloroquine see also my post on Chloroquine. Biological Approaches to Therapy of Pancreatic Cancer http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882228/ A triple combination of atorvastatin, celecoxib
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Colon and Colorectal Cancer
Here are a few relevant elements. I will further improve the page when possible: Artesunate (Artemisinin): Cheap anti-malaria drug shows promise against colorectal cancer Monocarboxylate transport inhibition potentiates the cytotoxic effect of 5-fluorouracil in colorectal cancer cells In other words, Quercetin, Ibuprofen, Statins, Apigenin, etc. will help while Butyrate may not help in this specific case,
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ACC (Adrenocortical Cancer)
Recent (June 2018) case report indicating that checkpoint inhibitors that target PD-1 may be dangerous in some ACC patients: Rapid disease progression in a patient with mismatch repair-deficient and cortisol secreting adrenocortical carcinoma treated with pembrolizumab https://www.sciencedirect.com/science/article/pii/S0093775418301258 An important conclusion: After all the literature I read on ACC, I conclude that hormone producing ACC tumors are highly
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