The Anti-Allergic Drug That Increases Appetite & Kills Tumors

The Anti-Allergic Drug That Increases Appetite & Kills Tumors

Author: Daniel S, PhD; Last update: January 31st, 2021 Introduction Dear Friends, With this post I would like to highlight a cheap and accessible drug that I think it is good to be aware of, given its anti-cancer potential. Its name is Cyproheptadine, it is FDA approved, and in most countries is sold over the
Continue reading The Anti-Allergic Drug That Increases Appetite & Kills Tumors

A Lower Cost Alternative to (anti PD1/PDL1) Immunotherapy?

Author: Daniel S, PhD; Last update: January 31st, 2021 Dear Friends, I just came across a recently published paper by scientists and MDs in oncology that deserves to be addressed in a post on this Blog. The scientific results come from MD Anderson Cancer Center & University of Alabama at Birmingham in USA, as well
Continue reading A Lower Cost Alternative to (anti PD1/PDL1) Immunotherapy?

A Silver Bullet to Kill Cancer

Background Silver was the most important antimicrobial agent available before the introduction of antibiotics. The natural antibacterial action of silver has been known already since antiquity. The Romans used the effects of the silver for water purification. It is likely that silver nitrate also was used medically because it was mentioned in a pharmacopeia published
Continue reading A Silver Bullet to Kill Cancer

Propranolol: A “Heart Drug” that Stops Cancer Progression due to Stress

Background:   Propranolol is a drug commonly used to treat high blood pressure, irregular heart rhythms, pheochromocytoma (tumor on a small gland near the kidneys), certain types of tremor, and hypertrophic subaortic stenosis (a heart muscle disease). It is also used to prevent angina (chest pain), migraine headaches, and to improve survival after a heart
Continue reading Propranolol: A “Heart Drug” that Stops Cancer Progression due to Stress

Hippo Pathway: Regulating Organ Size & Cell Proliferation

Background and Mechanism: Interestingly, a few years ago it has been published in Nature magazine a study reporting that glucose, the main energy source used for energy generation in cells, regulates the Hippo pathway (specifically its downstream effector YAP)(Ref.). This is very interesting and ground breaking because with this research it has been indicated for the first time
Continue reading Hippo Pathway: Regulating Organ Size & Cell Proliferation

Pyrvinium Pamoate: An Anti Worm Drug with Important Anti Cancer Potential

Summary: Pyrvinium Pamoate (PP) (a quinoline-derived cyanine dye) is an relatively non toxic anthelmintic drug, FDA-approved, sold over the counter in countries like Sweden, Norway, Denmark used to treat pinworms in humans and animals. During the recent years this compound has been shown to effectively inhibit various cancer cells types such as brain, colon/colorectal, breast, prostate, etc. and
Continue reading Pyrvinium Pamoate: An Anti Worm Drug with Important Anti Cancer Potential

Chloroquine & Hydroxychloroquine: supporting chemo effectiveness and more

Summary Chloroquine is an anti-malarial drug available at pharmacies for people travelling to area with malaria risks as well as to address other health challenges. Note: based on a RGCC chemosensitivity analysis I have seen at a German clinic, Hydroxychloroquine has been effective in killing the cancer cells of 5 out 7 patients that were tested.
Continue reading Chloroquine & Hydroxychloroquine: supporting chemo effectiveness and more