Background: Propranolol is a drug commonly used to treat high blood pressure, irregular heart rhythms, pheochromocytoma (tumor on a small gland near the kidneys), certain types of tremor, and hypertrophic subaortic stenosis (a heart muscle disease). It is also used to prevent angina (chest pain), migraine headaches, and to improve survival after a heart attack.
Continue reading Propranolol: A “Heart Drug” that Stops Cancer Progression due to Stress
Background and Mechanism: Interestingly, a few years ago it has been published in Nature magazine a study reporting that glucose, the main energy source used for energy generation in cells, regulates the Hippo pathway (specifically its downstream effector YAP)(Ref.). This is very interesting and ground breaking because with this research it has been indicated for the first time
Continue reading Hippo Pathway: Regulating Organ Size & Cell Proliferation
Summary: Pyrvinium Pamoate (PP) (a quinoline-derived cyanine dye) is an relatively non toxic anthelmintic drug, FDA-approved, sold over the counter in countries like Sweden, Norway, Denmark used to treat pinworms in humans and animals. During the recent years this compound has been shown to effectively inhibit various cancer cells types such as brain, colon/colorectal, breast, prostate, etc. and
Continue reading Pyrvinium Pamoate: An Anti Worm Drug with Important Anti Cancer Potential
Summary Chloroquine is an anti-malarial drug available at pharmacies for people traveling to area with malaria risks. Note: based on a RGCC chemosensitivity analysis I have seen at a German clinic, Hydroxychloroquine has been effective in killing the cancer cells of 5 out 7 patients that were tested. It is one of very few available drugs
Continue reading Chloroquine & Hydroxychloroquine: supporting chemo effectiveness and more