Posted by: @kimster

Dear Friends,

Hi, I'm creating this topic as noticed that "Marine Microalgae" is a potential source of anti-cancer compounds.

 

I noticed this "Spirulina Platensis" supplement at local pharmacies, so I tried to find some information to understand it:

https://www.hindawi.com/journals/ecam/2016/7803846/

Medical Application of Spirulina Platensis Derived C-Phycocyanin

11 May 2016

Along with the development of marine biological pharmaceutical research, high-effective and low-toxic drugs and functional foods isolated from marine organisms have become a new field of pharmacy and bromatology.

The pharmacological actions, such as anti-inflammation, antioxidation, antitumor, immunological enhancement, and hepatorenal protection of C-phycocyanin (C-PC) from Spirulina platensis, have been reported,

and C-PC has important value of development and utilization either as drug or as functional food.

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After that, I noticed the following:

 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983296/

Marine Microalgae with Anti-Cancer Properties

2018

 

 

https://www.sciencedirect.com/science/article/pii/S0753332218370318

Microalgae in Modern Cancer Therapy: Current Knowledge

2019

 

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Thanks.

Kimster

 

 

 

 

 

 

 

 

 

Dear Kimster,

Thank you very much for sharing this information. Have you found any published case report with patients doing well on this one?

Kind regards,
Daniel

@daniel

Dear Daniel,

Hi, thank you for taking note of this topic.

I have not found any published case report --- as just started to try to read a bit to try to understand this "Spirulina Platensis" supplement first.

I noticed that the Search(Spirulina) in this website found some comments mentioning it.

I'm still learning, so could not share much.

Hopefully, there are friends who could share more about this topic.

Thanks.

Kimster

Hi, I'm still reading whenever free - just notied the following, but yet read further:

https://pubmed.ncbi.nlm.nih.gov/16740358/

The recombinant beta subunit of C-phycocyanin inhibits cell proliferation and induces apoptosis
2007

C-Phycocyanin (C-PC) from blue-green algae has been reported to have various pharmacological characteristics, including anti-inflammatory and anti-tumor activities.

:

:

Under the treatment of the C-PC/beta, depolymerization of microtubules and actin-filaments were observed.

The cells underwent apoptosis with an increase in caspase-3, and caspase-8 activities.

The cell cycle was arrested at the G0/G1 phase under the treatment of C-PC/beta.

In addition, the nuclear level of GAPDH decreased significantly. Decrease in the nuclear level of GAPDH prevents the cell cycle from entering into the S phase.

Inhibition of cancer cell proliferation and induction of apoptosis may potentate the C-PC/beta as a promising cancer prevention or therapy agent.

Thanks.

Kimster

Hi, just noticed the following information, so just adding here:

https://www.newhope.com/news/human-research-indicates-supportive-role-spirulina-fighting-cancer

Human research indicates supportive role for spirulina in fighting cancer

2002

An earlier double-blind peer-reviewed human study conducted in India and published in "Nutrition and Cancer," found that consumption of one gram of Spirulina daily for one year resulted in a 45% remission of oral leukoplakia in tobacco chewers compared to a 7% response in the placebo group.

Oral leukoplakia is characterized by pre-cancerous lesions in the mouth.

Additional research conducted at Harvard University had showed similar benefit with extracts of Spirulina in combination with natural beta-carotene in reducing chemically induced oral tumors in hamsters.

https://pubmed.ncbi.nlm.nih.gov/8584455/

Evaluation of chemoprevention of oral cancer with Spirulina fusiformis

1995

This is the first human study evaluating the chemopreventive potential of SF (Spirulina Fusiformis).

Thanks.

Kimster

Hi, also adding the following information here:

https://doctorlib.info/health/food-medicine-future/7.html

Superfoods: The Food and Medicine of the Future

Spirulina: Protein Queen

Spirulina is rich in a brilliant blue polypeptide known as phycocyanin.

This blue pigment helps induce the production of more stem cells found in bone marrow.

:

:

Immune System Booster

Spirulina is a powerful tonic for the immune system.

In scientific studies of humans, mice, rats, hamsters, chickens, turkeys, cats, and fish, the introduction of spirulina into the diet consistently improves immune system function.

Spirulina accelerates production of the humeral aspect of the immune system by helping to increase the production of antibodies and cytokines, including interferons and interleukins, allowing the body to better protect against invasive microbes and viruses.

Spirulina accelerates the production of the cellular immune system by helping to increase the production of bone marrow stem cells, T-fighter cells, macrophages, B-cells, and the anti-cancer natural killer (NK) cells. Scientists have almost universally observed that spirulina causes macrophages to increase in population and to become more effective at killing microbes even in spite of stresses from environmental toxins and infectious agents.

Once the production of new immune system cells circulate in the blood, they begin to concentrate in the adenoids (tonsils), appendix, bone marrow, liver, lymph nodes, spleen, and thymus, increasing overall health and immunity.

The primary active phytonutrients in spirulina responsible for improving the immune system include:

·        Research indicates that the more beta-carotene you have in your diet, the longer you will live. Plant- and algae-derived beta-carotene inhibits the replication of certain cancers in animals and in humans.

·           A type of lipo-polysaccharide known as LPS a long, complex sugar molecule attached to a molecule of fat/oil via a covalent bond.

·           The stem-cell-producing blue antioxidant known as phycocyanin.

A double-blind peer-reviewed human study conducted in India and published in Nutrition and Cancer, found that the consumption of one gram of spirulina daily for one year resulted in a 45 percent remission of oral precancerous lesions in tobacco chewers compared to a 7 percent response in the placebo group.

Thanks.

Kimster