Your Contribution Needed on Breast Cancer Story from Emad

Dear Friends,

On the same line as the post from Ergin, I would like to invite you if you could please share here ideas and experience that may be relevant to Emad and his dear mom.

Off course, as the disclaimer is also stating, this website is not intended to offer medical advice but to try and get together as much collective knowledge as possible, so that finally, together with our medical doctor we make informed and successful decisions regarding our treatment strategies.

Here is the message from Emad:


Dear all , my name is Emad Abushofa , from Libya

In 2012 my mother diagnosed with metastatic breast cancer , Estrogen positive , Her2 negative

Tumor marker was about 500, she was walking hard because of mets in her legs

After 9 cycles of chemo then radiotherapy , the tumor marker declined to 30 , and she became able to walk normally again

Then she started on hormonal therapy , but the markers were raising slowly

Until August  2015 , the tumor marker became 2000 , so decided to return to chemo

She took  6 cycles of taxotere ( also I added DCA + Natural protocols like Budwig , MSM LIPH , Juicing , Liposomal Vit C)

The tumor marker declined from 2000 to 353

After another 3 cycles , but this time only chemo , the marker rised to 712

Then the oncologist changed the chemo to 5FU and venorelbine , 2 cycles with DCA , the tumor marker declined to 450

Then I stopped DCA few days and didn’t give it before chemo , the marker rised to 558

Then again DCA with chemo + artimisnin + baicaline , decline to 450

Then I run out of everything , marker rised to 714

Changed the chemo to Gemzar + Carboplatin , 3 weeks per cycle

Cycle 1 : chemo alone , decline from 714 to 685

Cycle 2 : chemo then DCA IV added lately (not before chemo) , raise to 699

Cycle 3 : chemo + DCA IV , decline to 517

Cycle 4 : chemo + DCA IV + one shot half dose Salinomycin base version , decline to 408

Cycle 5 : chemo + DCA IV + one shot full dose Salinomycin base version , decline to 317

Then we stopped 2 weeks because of blood transfusion , also runout of Sal

Cycle 6 : 2 weeks DCA IV only, then half dose chemo with DCA IV , raise to 380

Cycle 7 : chemo + DCA IV , decline to 350

Cycle 8 : chemo + DCA IV + 3 shots Salinomycin sodium salt version , decline to 330

Cycle 9 : chemo + DCA IV + 4 shots Salinomycin sodium salt , decline to 320

Then another stop for 2 weeks because of blood transfusion (DCA IV  + one shot Sal)

Cycle 10 : 75% chemo , DCA IV + procaine IV + high dose lansoprazol + 1 shot Salinomycin sodium salt in the same day of chemo

Tumor marker raised from 322 to 607


Few notes :-

1-     I started to give procaine IV just 2 weeks ago , 2ml of 2% solution , half an our before DCA IV

2-     My mother always had a marked tremor when using Sal , sometimes strong

3-     First 3 days of chemo I give my mother 180mg lansoprazole per day , then 80mg for other 4 days

4-     The mets on my mothers bones are small and stable for along time , but the mets in her liver are trying to grow fast , 5 spots less than 1cm , 3 spots between 1cm to 2cm

5-     Im not sure about the last chemo cycle, we felt like they didn’t give my mother the proper dose

Now I only have DCA + procaine, I have 100ml MethylGlyoxal , no more Sal


I will be happy to listen from you , your opinions will always help us

Thank you so much

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603 thoughts on “Your Contribution Needed on Breast Cancer Story from Emad

  1. Dear Emad,

    Thank you so much for your clear summary and congratulations for what you did for your dear mom so far. I am sure you will find your way forward and will do my best to give you some ideas and maybe more. I will reply to you partially here and partially on your e-mail. First I need to check a few things.

    Kind regards,

    1. Thanks a lot Daniel

      it looks like I did a lot but not that much as most of the time I’m going around DCA , and recently Sal

      I wish if I can get 3-BP , sad that its hard to be shipped to our country in a good condition

      I’m in love with all these treatments and wish to use them all

      after all I was inspired by you all the time and still 🙂

      1. can we really be sure that the long shipment makes it useless? I mean, i know 3-bp is not stable at room(or god knows what..) temp for 1-2 weeks – but maybe the changed version is still useful as anticancer agent ..

        1. good question , but I don’t know

          there was a great thread about 3BP on cancercompass , I don’t know if you know about it

          but I think they discussed this issue , I don’t remember exactly what they said but I felt like its gonna loose some of its effect

          maybe Daniel have some thoughts

          when we order from a chemical company we used to receive the shipment after 2 weeks from sending it , so I need to make sure that 3-BP could somehow stay good in 2 weeks room temperature

            1. Hi Daniel , two questions only

              1- how many days can 3-BP stay in a room temperature ?

              2- is it worth trying to obtain 3-BP even when the shipping time will be 1-2 weeks ?


              if 3-BP used to be stable , probably I would be using it for months

              really wish to have it

            2. Hi Emad,

              In powder form, and as long as is not exposed to high temperatures, and humidity, it should stay unchanged for weeks. Long term storage is 4C. Once made solution, the stability is very short, strongly depending on temp and pH of the solution.

              There was once a report from someone who receive 3BP from China and when the package was opened there were vapors coming out of 3BP which was not anymore in the form of powder but some sticky substances. Probably this was stored in a high humidity place, and opened. Most probably it was in that form even prior to be sent.

              We never used 3BP from China. Always western suppliers.

              I hope this answers your questions.

              Kind regards,

            3. Sounds good !!! great !!!! wonderful !!!!

              I decide to let my next protocol nothing other than (Sal + 3-BP) with chemo and DCA probably

              I’m excited to receive 3-BP , as I know Santa Cruz really have a very good quality and carefully shipping there products in the best shape 🙂

            4. guys, what suppliers do we have from western countries that send to private pple and not just universities? is it just santa cruz?

            5. no , Santa cruz are selling only to universities , just like other western suppliers

              but you should only get an email address that proves to be related to a university

              if some university have a website with this domain “”

              then all you need is an email like “[email protected]

              if you didn’t find a way to access email like this , then probably you may have a friend who can

              in our case , my father is a professor in Tripoli university and it was easy for him to have one

  2. Dear Emad,
    With all respect, i know you’ve been here much longer than me.
    Where is Metformin? If you didn’t use it…….. it’s good stuff.
    Any special reason for not including it or is it something you forgot to mention?

    Best wishes,

    1. I used it for a while , maybe for 2 months

      I didn’t notice any change with it

      quote :
      Then the oncologist changed the chemo to 5FU and venorelbine , 2 cycles with DCA , the tumor marker declined to 450
      Then I stopped DCA few days and didn’t give it before chemo , the marker rised to 558

      the 2 results above I was using metformin with it , also some others like chloroquine

      maybe I will give it another try this time

      my best wishes for you too dear Alex

      1. I find that is necessary, what was the dose used by you?
        Also metformin is greatly amplified anti-cancer when combined with aspirin or diclofenac or maybe even citric acid.
        Mebendazole would also be a great addition to those, still unaware of what the best dosage would be.
        If you are asking what the effects are, i cried tears of joy today, seeing how my mother is feeling better. No marker number.
        We are also using HCA, CA, ALA.
        If you feel something is out of place, i would go check blood, hormones, glands, they do play a big role, and no chemo will be able to help much so long things are out of balance. (So i feel).
        Don’t forget the liver, immune system, the gut. I hope your mother has been doing coffee enemas too, and going on a vegan diet
        IT HELPS!!! Every bit of good food counts, and every bit of bad food is very bad.
        Also, i would also check the dental situation, there is data out there pointing to breast cancer and major hidden tooth issues.
        Thermografic imaging….!?
        If the tumor is within “reach” consider heating the breast, free hyperthermia?!?!? 50C-60C hot water, steam. Eh?

        Congrats on getting so far with your mother.
        Best wishes.

        1. I used 1g metformin only , with the dose you mentioned , it means I should use 2g daily

          no coffee enemas unfortunately

          you are totally right about the good food and bad food , they are really a major role in all this

          there is no hyperthermia available here in our country but if my mother had the chance to be treated outside Libya , hyperthermia will be a good choice indeed

          but after all I’m happy to see you happy man , nothing is better than staying healthy in this life 🙂

          take care my friend Alex

          best wishes

            1. yes they are really interesting , I have watched all the episodes of The Truth About Cancer

              sad we missed the chance to correct my mothers body when she was on hormonal therapy for 2 years

              now after she heavily treated with chemo it become very hard , but still not something impossible

            2. I am curious what you would change if you had the chance to go back in time?
              i know i would reconsider suggesting surgery, it proved to be a mistake, solved nothing. Anyway….

            3. sad that we can’t change the time

              if I started to search alternatives since 2013 , probably I will go totally natural with my mother , treating the underling cause , correcting the body chemistry

              now after we started chemo since 1.5 year , it begins to be so hard to do what we should do , cancer is more aggressive , and our country economic problems become disaster

  3. If I were to guess, I’d say that the tumour marker rising that much during the last cycle could be due to taking a rest from chemo for the blood transfusion.

    ie. Maybe the tumour marker raised even higher during the rest, but still did fall to 607 with the chemo. So what looks to be a case of chemo stopping working might not necessarily be the case.

    At any rate, even if this were the case, this tumour looks incredibly aggressive. I would look into some off label medication.

    Like Daniel had told me earlier, Diclofenac might seriously potentiate the effect of DCA by downregulating MCT1 (I believe) and up regulating SMCT1.

    Daniel also spoke of inhibiting autophagy during chemo so as to take one escape route away from cancer cells which would normally temporarily protect them during stresses like the ones created through chemotherapy.

    I think I would keep the proton pump inhibitor that she is taking. I’ve read that it potentiates many forms of chemo.

    1. Hi Meech

      thank you so much for your notice

      we did blood transfusion before and also the chemo delayed same as the last time and even they give carboplatin only with no Gemzar , but tumor marker only raised from 317 to 380

      but the last time is totally different , I think like Daniel said , PPI are not a good choice with weak acids , this can describe what happen

      but really my mothers cancer is aggressive , and I can notice how its getting more and more aggressive every time , and I should blame chemo for that

      but in your regarding off label medications , I’m a little bit scared from using them too much , I don’t want to put more stress on the liver and kidneys

      diclofenac , metformin , chloroquine and others , I may give them another try

      this nearly used 25 chemo cycles , my mother is 50 years old , I hope she can tolerate it , she can live with chemo as she is not feeling weak or tired , but her bone marrow and other organs I’m not sure if they can stay good for long time

      my best wishes to you Meech

      1. From what I’ve found online, Metformin’s nephrotoxicity can be attributed to its increasing risk of lactic acidosis. However, risk of lactic acidosis is incredibly rare (around 3-5 people per 100,000). It’s also important to note that the vast majority of patients receiving Metformin are also diabetic, which would indicate probably some deal of kidney damage in the first place due to high prevalence of obesity, hypertension, etc. With this patient group.

        So I don’t want to go out and say “Metformin is fine to take and low risk” because I’m not an expert, but I think checking out exactly what the risk of kidney damage is with Metformin would be beneficial as it is a pretty valuable drug.

        I do understand the concern though. I only have one kidney so I also have to exercise a lot of caution with medications.

        Wishing all the best,

        1. metformin should be safe compared to most of the drugs , and really I believe I should return to use it again

          sorry to hear that you have one kidney Meech

          you are inspiring to all of us on the way how you are living and taking care of your self 🙂

            1. Hi Meech,

              Addressing one of your points on protecting kidneys:

              1. As you said, a tone of water
              2. Astragalus
              3. Alfacalcidol is a form of vitamin D helpful in people who have kidney problems.
              4. HDAC inhibitors such as Valproic Acid help against kidney toxicity induced by Cisplatin possibly others:
              5. Sylimarin can also protect against Cisplatin toxicity at the kidneys:

              Kind regards,

  4. Hi Emad,
    I felt that one day you will write those words.The rise in markers.Because it was stable.
    If you use salinomycin,it should be easy for you to use phlorizin or derivatives just before chemo.
    You must also read T4 depletion,for me it is one of the best in our hand for now.
    There is a serious and very good responce on breast ca.Please read it.
    I always find your comments in all treatments like chloroquine or mebendazole diclofenac.Where did they gone?
    Did you stop them?Or forget to write to your above post?
    You never used any angionegenis inhibitor as i see.
    You are not in a situation that words stopped.
    We will never give up.You are very strong,dont forget your words in our communications.
    Kind Regards
    Your brother who will always near you.

    1. Thank you always for your kind words and great help to our family Dear Ergin

      believe me I felt strong for the first time yesterday when I was waiting to receive the results

      I used to feel sick everyday when it comes to marker results

      I remembered how strong you have been to face the results each time 🙂

      regarding phlorizin is there any good source you know about ? or its only available in chemical companies ?

      T4 depletion is one of my choices , i will study it more and be ready to use it

      regarding chloroquine , mebendazol and metformin , i used them with some others , but i didn’t notice any deference , but also i didn’t give them more than a month or 2

      one of things that let me stop them is to not do more stress on the body , but maybe I’m wrong and my mother can easily tolerate them all

      i feel i must give them a serious try again

      and for angionegenis , i will look if i can have the cheap version of Thalidomide

      so much strategies , i need to think carefully for my next step , just like you brother , hope we find the key soon

      and i believe that we both could find it

      like John Cena said : never give up 🙂

      1. Hi emad

        The more i read about metformin the mire convinced i am its a must

        It affects both mito and nucleus, glucose level, igf…

        Im taking berberine insteaf of metformin, similar impact


        1. Very much agree Wondering. I am a little behind with my e-mails and responses to comments due to traveling, etc. but I thing you asked me a question about mito inhibitors. As we have seen from recent research even CA may do that. However, some of the most known inhibitors are Metformin, Doxycicline but also Salinomycin. Meclizine was another one – I wrote about it in the Phosphoethanolamine post.

          1. no worries, Daniel, i know you are not a robot capable of answering dozens of comments each day 🙂
            in the meantime i found your post regarding cachexia. i did not read it earlier as im not affected by cachexia – but i realised that you wrote a lot about about glutamin uptake inhibition and provided lots of hints again.

            in my comment to to you (and all) earlier i was a bit shocked that 3 studies claim that more energy is produced by the mitochondria in cancer cells than by the nucleus against the conventional wisdom. It is in contradiction with the the opinion on glyculisis of Seyfried, Swartz etc.. who claim that mitochondria is dysfunctional and more atp is produced by glycolisis. Probably the key in is in effectivity (36 vs 2, mitochondria vs glycolisis, so if nucles is used 90% of the time, mito is still producing more atp). But then we can not claim that :
            1) restoring mito will help – ) as it works already… against human survival
            2) blocking glycolisis will kill cancer
            3) Warburg was right

            there is MUCH confusion about this topic even among scientists..


            1. Hi W,

              good logic. However, blocking glycolysis is a good strategy for sure even if we don’t know the full picture why. Yeah, mitochondria could be functional in cancer cells but we know that glycolysis suppresses the immune system, therefore it is advantageous to suppress it, even if for no other reason. Best strategy is to rely on experiences, rather than theories if we can choose between the two. And you are right, people are confused about the Warburg effect, etc. incl. scientists.


            2. Wondering, you might be interested in this.

              More on metabolic issues in cancer. I found an article discussing these and Warburg, etc. E.g. Have you heard of oncometabolites? They argue that some of the metabolites produced by the cancer cell are actually oncogenic! Boggling the mind.

              “With this broadened view of what constitutes an oncometabolite, one could argue that the discoveries of two other oncometabolites, succinate and fumarate, preceded that of 2HG.” Here is the paper:

              Fumarate? Could it be that dimethyl-fumarate, the anti-psoriasis drug, ( here: ) competitively inhibits fumarate?

            3. Hi W, yes things seem complex and scientists are still learning.
              But what seems to be clear is that both glyco and mito have own functions in tumor development.
              There are many things to discuss on this line, but glyco is less efficient but much faster while mito is slower but much more efficient. Stopping glyco is very important because of so many reasons. For example, if you stop that there will be less fuel for mito, and mito would need to switch on other fuels, tumor will develop slower, less anti-oxidant will be produce to fight with reactive oxigen species produced by mito that may lead to cancer cell death, less lactic acid will be produced which signals the transition of body glutamine towards the tumor (e.g. cachexia will be reduced) and so on.
              So, depending on how much the tumor is dependent on the above processes, you may be able to kill the tumor by blocking glyco.
              If that doesnt happen, we may need to also use mito inhibitors. This is why I like Metformin, Doxycicline, Salinomycin.
              Swartz technique is relevant because is addressing something else: not inhibiting mito but its output which represents the building blocks required for cellular division. As I discussed in one of my post and as shown by some of Schwartz patients, tumor cells may find a way around that inhibition by activating an enzyme that can convert acetate in acetyl-CoA.
              In the end we need to think well and use a cocktail of elements to address various escape routes. But not just jump on some treatment option because we like how it sounds. Instead, put a treatment strategy in place depending on our own situation, which is different from patient to patient. Do do that, we already have many tools discussed on this website. In the best case, with that we will kill the tumors, in the worse case we will slow them down. But to me, based on my personal experience, publications of Schwartz and all the other work referenced in my posts, the outcome will be better than not doing anything, when we have to deal with advanced cancers.

              Kind regards,

            4. Sure, you are obviously right. I find it though confusing that many scientists on the “metabolic” side keep telling how unfunctioning the mito is, while it is producing mire atp according to several studies now. Cheers, w

            5. another nice article mentioning another fuel for cancer..cellular signals. crazy. Still i believe blocking glutamine and cancer must lead to apoptosis in a wide range of cancer.


              “Glucose is not the only driver of cancer cell growth. Certain forms of cancers have also been shown to rely heavily upon glutamine as a source of fuel. Cancer cells have evolved a number of different ways of acquiring the amino acid from host tissues. In fact, it appears that cancer cells may derive energy by literally consuming cellular signals. Zhao and colleagues came upon this discovery when investigating the role of exosomes, which are tiny pouches of proteins and nucleic acids that transmit information between cells. The team was surprised to find that not only were the cancer cells receiving these signals from other cells, they were using them as a source of energy, consuming amino acids directly from the exosomes. This is another example of how remarkably resourceful cancer cells can be – drawing in glucose and amino acids from the environment as building blocks for tumors.”

          1. thanks Helga.
            I was thinking about adding something like this but Daniel wrote that with oral administration much of it leaves the the body in stool …so probably not too effective if not via intravenous way. pity.

            1. I take turmeric with 10% black pepper and add also dry ginger. I dissolve all of them in soda water (or fizzy mineral water). I swear to you I can feel the effect. However, mostly probably against inflammation as I have not been diagnosed as having cancer (finally found a gynecologist here, who will examine me in early June – I wonder what women do here if they need one urgently, e.g. pregnant? one would think that you’d have to wait 3 months for an exam in some 3rd world country but they might have actually a better care than this particular little country in the EU, damn).

            2. Helga

              Sorry to hear of your situation. What country do you live in?

              I find the black pepper really helps with the absorption of Tumeric and Curcumin. I have not thought of adding dry ginger, that would really help in my opinion.


            3. Dear Paul,

              it is a small country in Europe, overrun by the Soviets in 1968. It is fine but maybe there is a shortage of gynecologists/doctors here or perhaps too many women live in this city. It is a rather Kafkaesque situation 🙂

              I am glad you find turmeric/black pepper also useful. I think that carbonic acid (in the soda water) also helps with the absorption. And ginger has a great anticancer effect in itself. It is worthwhile to combine it with citric acid. My bump in my belly greatly diminished since I am taking CA. Perhaps Ergin is right and it is not ovarian cancer after all. Nevertheless, I still have a lot of sweating. My other ‘candidate’ is my right lung, which produces a lot of mucus. An X-ray didn’t show a mass. Does anyone know what % of lung cancer can be seen in an X-ray?

              How is your sister? She has lung cancer if I am not mistaken, right?

              Kind regards,

            4. X ray,
              Dear Helga.
              When the doctors looked at my mother’s xrays they couldn’t see a thing…… not one.
              Scanner showed the tumor very very clear.
              Bone will show contrast, for a tumor to be more than transparent, it will have to be calcified.
              The shape may look like something else, not a ball of tissue but some claw shape… etc etc.
              Next to that shape you would have the soft tissues that are for the most part, transparent to xray

              Many Thanks,

      1. Ergin, brother.
        Still did not received that package from you yet.
        How is your mother? How are you? You are online on skype but…. no answer.
        Interestingly mother is feeling better with no DCA maybe the other things are doing very good for her.
        Today she feels very good. More mobility, less inflamation.
        I also add 100mg Mebendazole X3
        And i alternate aspirin with diclofenac from day to day.


        1. Hi Alex,
          I hope it is not in the customs.I will send you the tracking number tomorrow.
          Skype is open in office i think.
          After my mother began mebendazole,diclofenac,celecoxib etc., her pain on bowel released.
          May be it is because of the pain killer effect of them.Or they helped,i dont know.

          1. Ergin.
            Today i cry tears of joy, seeing my mother feel better, i reminded myself of all the help i received.
            It was a very nice day here for us, a rare event in my life… me crying tears of joy. Thank you!!! Daniel, everyone here.
            don’t give up metformin bro, it helps very much. Vegan diet, no bread, oil, fat, very little fish 1/week same for egg.
            Diet helps with bowel problems too. and enema.
            Don’t forget the immune system.
            1 fruit before food helps with bowel problems too.
            Don’t forget water, good hydration

            Best wishes,

    1. hi Ergin,
      thanks – i have heard about cimetidine from you and Daniel and i already bought some. it seems to have several anti cancer properties.

      Havent you think about random pills having much anti cancer effect? there are reports showing that antibacterial pills, anti histamine pills, anti inflammation pills anti worm pill, anti malaria, blood pressure reducer pills, anti diabetes pills anti malaria pills, even anti acne pills have anti cancer properties. Maybe one with cancer should take ALL what she can bear from above pills and the result would be surprising, a real anti cancer cocktail. There would be more synergy than negative interference. I mean it. And if you think of the brian cancer cocktails, for instance the one of Brian Williams – that pretty much relies on boring pills like anti acne pills. probably its beacuse cancer is the disease of the diseases – it uses any method it can grasp – and it can mimick some other conditions hence…. and pills curing those other conditions can be therefore effective.

  5. Dear Emad,

    As promised, here is my addition:

    This is speculation for now. But, based on simple logic I would expect that Proton pump inhibitors will help the chemotherapies that are weak bases (most of the chemos are this type) and will NOT help the chemos that are weak acids. Let’s try to verify this hypothesis with checking the literature:

    It has been shown that proton pump inhibitors can increase the effectiveness of erlotinib: Indeed erlotinib is a weak base:

    It has been shown that proton pump inhibitors can increase the effectiveness of Mtor inhibitors such as rapamycin: Indeed rapamycin like all Macrolides, is weak base:

    And there are many examples of chemos that are helped by Proton Pump Inhibitors. These are just a few.

    However, some chemos are weak bases and others are weak acids. Here is a good reference to get a feeling on that

    Now, you use Carboplatin and Gemcitabine

    But Cisplatin/ Carboplatin seems to be a weak acid: “Cisplatin, being a weak acid, exhibits significantly greater uptake from acidic milieu, resulting in increased intracellular accumulation and heightened cellular toxicity.”
    Carboplatin also seems to be activated in acidic environment

    Gemcitabine on the other hand is a weak basis

    Based on the above it may be that the drug is most active for your mom is Carboplatin, and the use of proton pump inhibitor prior to Carboplatin may lower its activation due to lower acidity around the tumor? Note that this is just a hypothesis but this would be the only thing that would make sense to me other than just that the tumor would not respond anymore.

    However, against my theory from above there is literature suggesting that Proton pumps prior to Cisplatin can help: Yet, maybe in this trial it worked because chemotherapy was preceded by three days esomeprazole and the first day they gave Taxol and only in day 4 they used Cisplatin.

    Here is a paper that supports my hypothesis: Tumor acidity, ion trapping and chemotherapeutics I. Acid pH affects the distribution of chemotherapeutic agents in vitro and is highly cited so it is a paper of reference in the field.

    To conclude, based on literature and your clear summary, I would do the following: pretreat with Omeprazole during a few days and stop, use Gemcitabine which is a weak basis in day one. Use Carboplatin in day 4.

    If your doctor doesn’t agree with this, I would stop the use of Omeprazole as long as Carboplatin is used. In addition, according to your summary I would continue with Salinomycin.

    I hope this helps you and others.

    Kind regards,

        1. Hi Ergin,

          You may also want to read this: “Low extracellular pH augments cellular uptake and cytotoxicity of weak acids such as cisplatin (36) and alkylating agents (37), while high extracellular pH …” Ref.
          Another good reference on this subject

          According to this aspect (acid vs base) Gemcitabine is weak base and Oxaliplatin seems to be weak acids. Based on this, if it would be me, I would use the two at a few days difference and pretreat with Lanzoprazole prior to Gemcitabine. After that stop with Lanzoprazole, and after a few/several days use Oxaliplatin. If this is not an option, than it make sense not to use proton pump inhibitors.

          The point following this new aspect we learned, is that we need to verify what is the chemotheraphy we use, if it is acid or base and depending on this use or not proton pump inhibitors prior to chemo. Also, it means that we should not use NaBicarbonate prior to acidic chemos.

          Out of all this, it becomes clear that we know a lot but we also still have things to learn. Let’s hope that this new aspect will help us to improve the effectiveness of chemos in the future.

          Kind regards,

    1. Thank you so much Daniel for this great details about PH roles in cancer and chemotherapy

      its probably the reason for what just happened , as i didn’t give my mother more than 60mg lansoprazole and some times i don’t give her at all , except the last time i gave her 180mg for the first 3 days of Carboplatin Gemzar combination

      but also this made me worried about quickly adding things with chemo without proper knowledge

      also still not using DCA in the first 4 days of chemo because of Dr Akbar Khan talked about possible interference , i mentioned this to you in the past , even when we don’t find the reason but doing something wrong with chemo will not lead to good results

      but also we need to take some risks at the end

      your opinions are always helping , thank you very very much

  6. I would try metronomic chemotherapy plus lansoprazole or omeprazole, metronomic vinorelbine seems well tolerated, maybe add celecoxib.
    But for the liver mets this may be not enough, the standard palliative choice for liver mets is radiofrequency ablation.

    1. Hi Ovidiu,After learning this tech.from Daniel again,i am searching for cyroablation.
      It looks better than RFA.
      Does anybody has experience about it?
      Because there is no bleeding after cold ablation in -40 centigrate,tumor seeding will be very low.
      I like it very much but you can not use it on everywhere,like bowel.Necrosis is dangerous on some organs.

    2. Hi Ovidiu

      I’m always reading your comments , I’m learning things from you each time , your opinions will indeed help 🙂

      i wish that we did metronomic chemo from the first days , before cancer become more aggressive

      regarding celecoxib , (as a medical student) they used to teach us that celecoxib may damage the heart ?!

      but some doctors don’t believe on this , what do you think about it ?

      1. @Emad: you don’t have to use a high dose of celecoxib, and only use if the metronomic chemotherapy induces Nfkb (like etoposide and cyclophosphamide do, I don’t know about vinorelbine).

        Other observations: the blood transfusions can contribute to chemo-resistance, that’s from my personal experience, after such a transfusion what previously worked (although barely) stopped working (CEA rose as without treatment). I believe that the blood may come from people who do this blood-giving for a living and their blood contains extra growth factors, which can increase angiogenesis and chemo-resistance.
        Gemcitabine is responsible for the low erythrocytes and platelets, and the oncologist may prescribe erythropoietin, and this would be a big mistake. It makes cancer cells more metastatic and chemo-resistant.
        Erythropoietin activates cell survival pathways in breast cancer stem-like cells to protect them from chemotherapy.
        Erythropoietin and drug resistance in breast and ovarian cancers
        Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal.
        In my father’s case, after Erythropoietin the Gemcitabine + Curcumin + Metformin + Disulfiram that kind of worked stopped working. The oncologist believed it was only resistance to Gemcitabine, but it was worse.

        1. oh my !

          That’s horrible , its too scary I feel like I’m loosing it >_<

          it really looks like blood transfusion is doing something wrong here as things started to change after the first transfusion !

          or maybe its for another reason we don't know about

          we still didn't use Erythropoietin , I hope not to use it , but receiving blood is something we can't runaway from

          chemo will continue lowering the blood counts and we will need more blood each time , without blood we can't continue on chemo and we still far away from having another alternative

          its like a closed circle

          this is terrible

          but really Ovidiu how do you think is the best way to protect from making cancer more aggressive after receiving blood ?

          i hope dear Daniel give us his opinion on this

          1. I didn’t say that the cancer would become more aggressive after a blood transfusion, but after Erythropoietin. Growth factors in the blood would probably return to normal levels after a while, but IMO it’s likely that chemo won’t work soon after a transfusion.

            There is another thing, if your mother took antibiotics to treat some infection (due to poor blood formula), this can also decrease the efficacy of chemo.
            Well-balanced commensal microbiota contributes to anti-cancer response in a lung cancer mouse model.

            And if you are still going to use Carboplatin + Gemcitabine, maybe you can add Noscapine (I couldn’t get it for my father).
            Apoptotic effect of noscapine in breast cancer cell lines.
            Enhanced anticancer activity of gemcitabine in combination with noscapine via antiangiogenic and apoptotic pathway against non-small cell lung cancer.

            1. Dear Ovidiu , sorry I forget something that maybe looks important but I’m not sure if it was the cause

              actually we did the blood transfusion after 48 hours from Carboplatin + Gemzar infusion

              we used to do blood transfusion at the end of the cycle but last time we did it after just 2 days

            2. I have to put Noscapine in my mind , things look more clear after your comments here Ovidiu

              thanks a lot

            3. Hi Ovidiu,

              do they add erythropoietin or that stimulating agents to patients who need/get blood transfusions? One has to be careful about it because it may increase thromboembolism: Reference

              Venous Thromboembolism and Mortality Associated With Recombinant Erythropoietin and Darbepoetin Administration for the
              Treatment of Cancer-Associated Anemia

              Conclusions: Erythropoiesis-stimulating agent administration to patients with cancer is associated with increased risks of VTE and mortality. Our findings, in conjunction with basic science studies on erythropoietin and erythropoietin receptors in solid
              cancers, raise concern about the safety of ESA administration to patients with cancer.
              JAMA. 2008;299(8):914-924

    1. I’m considering phlorizin and Sal , they seemed to be the best things to add with chemo

      but really Ergin I didn’t know that I could find derivatives of phlorizin , you think they can work just like phlorizin ?

      hope yes , I love to use it soon 🙂

  7. hey Emad
    from above its clear that you helped your mom a LOT, maybe she would not be here without your actions.

    chloroquine is cheap and would help in my view;

    maybe avemar, wheat extract could help,:

    pls check ogfr status in your mothers cancer, maybe ldn could help, in that regard pls search back daniels warning, :

    how about 3-bp if things go really south?

      1. Hi wondering , thanks for your opinions and concern 🙂

        yes i think I’m gonna add chloroquine and the other off label medications that may help

        regarding Griseofulvin , which one you think is the best : Griseofulvin or mebendazol ?

        i tried mebendazol 600mg daily for about 1 month , and didn’t notice any help , also not sure about the quality

        and about 3-BP , i really love and wish i can use it , but the big problem with it is that it could not stay in a good condition in a room temperature for few days

        and there is no company that can offer fast shipping here to Libya , i don’t know how can i reach it

        1. Re griseofulvin and mebandazole, im afraid there is no way to Tell, but they dont work exactly the same way. Im trying to get these both currently.

          Re logistics and temp.. i have the same problem but i think i Will try if things dont get solved without it.

          1. I gave my mother mebendazol before up to 600mg daily , at that time we run out of DCA and the tumor marker climbed from 450 to 714 , it was a huge jump and I felt like mebendazol didn’t help in anyway , maybe I’m wrong

            but I will see if I find a good source for griseofulvin here in our country

            sad to hear that you are facing the same problems regarding 3-BP , I hope we both can get it one way or another

          1. it looks strange as other western chemical suppliers used to write that 3-BP cannot stay few days in a room temperature

            I will look around again , my wish is to get 3-BP with Salinomycin , I feel that they are the only combination that can make treatment possible without chemo

  8. Hi Emad,

    ketogenic diet is a good option to stop the cancer from growing. I am very convinced of its effect and believe it is a good boost for all the other treatments. There are lot of papers out there on this topic.

    Kind regards,

    1. Hi Veronika,

      Thank you. Ketogenic diet is very relevant. It is on my list of treatment approaches to address on this website. The only drawback with it is that it has to be restricted ketogenic diet, and that makes it a bit difficult for some patients.

      Kind regards,

      1. Hi Daniel,
        restricted one must be more effective but below study indicates that the normal version is also effective:
        (for others: restricted keto allows only 12g carbonhydrate per day, and 1g protein per body kg, the rest needs to be fat. overall calories are also limited).
        probably normal kemo with some intermittent fastings should also help
        But Yes, Seyfried promotes restricted keto and he has reasons for it.

    2. Hi Veronika

      you seem to know well about ketogenic diet , do you know about people who are doing both chemo and ketogenic diet ?

      some how I feel like its hard for patients to stick with ketogenic diet while they are on chemo , I’m not sure but maybe you have some thoughts

  9. Hi Emad (sorry, I addressed you with the wrong name above),

    Is your mother taking any ”re-purposed” drugs on top her current treatment? It might not be as potent as the substances you are using, but thanks to the low toxicity and significant efficiency it could probably add a lot of value? As suggested above, Metformin is probably well advised. You could consider combining it with Statins and cycle Doxycycline/Mebendazole. This is the protocol the Care Oncology Clinic prescribes.

    Perhaps also consider bisphosphonates to address the bone mets

    Dipyridamole is also a promising agent:

    “Fasting mimicking diet” to potentiate the chemo and protect the immune system, and periodically afterwards to boost the immune system. Google “Valter Longo”.

    What you are doing to help your mother is really quite amazing!

    Kind regards,

    1. Yes I will use metformin

      also my mother stopped bisphosphonates months ago due to the risk of osteonecrosis of the jaw , but she will return to it soon, the dentist made it clear that my mother can return using it without a problem

      thanks a lot for you contribution Carl , you and other friends help here is amazing too 🙂

      wish you the best

  10. Hi Emad,Please read it up to end.
    It does not have a killer effect but it changes resistant cells to a sensitive level totally after 72 hours.
    ”Low molecular weight heparin tinzaparin antagonizes cisplatin resistance of ovarian cancer cells”
    It helps on 100’s of genes related to cancer.So the other cancer types should benefit from it.
    My thoughts are very positive for tinzaparin.I wrote it 2 times on heparin post but no one is interested including me:)
    But with Daniel and alltogether with friends,we can work and search for it.
    I think tinzaparin deserves respect.
    Kind Regards

  11. Hi!

    Of course, Ketogenic diet is “must try”!
    I followed Patricia`s Daly advices! (check google and facebook).
    I had times when I followed it quiet strictly (measuring ketone blood levels, glucose), scaling products etc., but some times only low carb. But I had in my opinion serious side effect – blood cholesterol levels went UP (my total cholesterol was 9,…mmol/L) and I have some progression in my bones in theese 2 years. Among other things, Now I am on statins.
    Be sure what numbers You want to see in blood samples.
    off label must be more effective in my mind!

    kind regards,

    1. you remind me of some cancer survivors who beat cancer by going total natural but not with ketogenic diet

      like Chris Wark , he actually against ketogenic diet and he claimed that balanced diet is much more better

      hope you are doing good , I hope you beat up cancer soon , my best wishes to you

      1. Chris Wark is an opportunist.
        He makes claims to potentially millions of people who are reading, watching, listening and doing.
        People go blind into what he says and promotes without shame certain brands, products.
        He specifically promotes the use of certain brand named devices, supliments etc etc etc.
        Little to no science.
        Aggressive commercially oriented cult followed unable to touch kinda thing going on there….
        While i appreciate his latest series, oriented towards the natural…. i can not help but notice the commercial intentions behind his efforts. He’s doesn’t seem to be doing it to help people but rather to get people to help him. “please buy this”.
        “this will cure you 100%”
        “Disclaimer, nothing here will actually cure you”
        More or less a joke of an idea and character he is. A survivor with good intentions once maybe, but corrupted now Says me!!!
        If he got well from cancer i feel it’s just somewhat random… i doubt everyone would get the same result doing the same exact things or even better.
        TY Bollinger is more mature about things in my opinion, especially in his latest videos.


  12. I guess the most important thing is to maintain low blood glucose (3mmol). It is what Dr. Seyfried recommends.
    This is also achivable with normal ketogenic diet. Actually I am in touch with few breat cancer women who are on a normal ketogenic diet and either they are cancer free or the metastasis are stable.

    @ieva cholesterol is not a bad thing. See here:

    kind regards,

    1. HI, Veronika!

      Yes, Seyfried`s recommendation is blood glucose 3 mmol and ketone levels in blood 3 or more (starvation ketosis). That would be ideal proportion. All is about glucose ketone index:

      I don`t understand what You mean by “normal ketogenic diet”?

      I am not interested in herat desease and high cholesterol, my point is to minimize everything, who can drive cancer.
      And that is not only glucose, especially, in advanced cancers.

      kind regards,

    2. When I spoke with Dr. Seyfried, he didn’t outline what blood glucose values you should be getting. This was his quote:

      “You can gage the efficacy of metabolic therapy by measuring your daily Glucose Ketone Index (GKI) while under a medically supervised ketogenic diet. You simply divide your blood glucose value in mmol by your blood ketone value in mmol. However, most blood glucose meters provide glucose values in mg/dl. You simply divide this number by 18 to get the glucose value in mmol. It is our view that therapeutic efficacy will be potentially best with GKI values as close to 1.0 as possible. It is also best to measure the GKI 2-3 hours after eating.”

      So even if you’re above 3mmol/L, as long as your ketone levels stay in the range of your BG values, it seems like it’s okay?

    3. I wonder how much it may take to see effect from ketogenic diet ?

      and is it easy to stay in the proper ketone levels or its sometime going out of control ?

      1. It takes few days for body to start to make ketones, it like transitional period, maybe with keto flue like symptoms. Dr.Seyfried sugest just 3 day fasting and then You are switched :). I did not fast for 3 days. I followed carb restrictin to 20g/day, protein ~60-100g/day, fat ~100-120g/day. My ketones were ~1-2mmol, but I mentioned good ketones number growth when I combined it to intermittent fasting – my ketone numbers went to 3.5 or even higher and i felt very good and clear minded. I liked it.
        At the first time body will tend to go back to glucose burning, but with time, it will switch to prefer ketones. But it can take a lot of time. MCT oil can help (I have not used it). I take pure coconut oil (there is some connection with medium chain triglycerides in this oil and how our body to use it). MCT oil is pure medium chain triglycerides and thus maybe better not to get high cholesterol levels.
        Everything that stress You can put You off keto state – even coffee, running, (I am not sure about hypothermia :), but think that also will stop keto state).

        In my mind for us is better to focus on intermittent fasting with just low carb diet (just make fasting windows for 12-18 ours or what Your body prefers). It should minimizes Your glucose levels, minimizes insulin spikes (and IGF-1) and as Carl mentioned – there are other huge benefits with intermittent fasting. And do not eat anything with hidden sugars.

        have a good day,

  13. Dear Emad,

    I am not sure if Daniel already mentioned this but DMSO is something that is also worth to look into: Allegedly it is a fantastic solvent, it will penetrate the skin and whatever you add to it, will be delivered to the tumors with the help of DMSO. I have never tried it but I come across it every now and then on alternative cancer treatment websites. It will work with both acidic and basic components. In fact the concept “pH” does not apply to it. It will work well with colloidal silver.

    Some places cesium chloride is also recommended with it but I heard it is a dangerously alkalic molecule and it can cause harm. However, DMSO itself is pretty harmless and a very useful chemical.

    ‘…it was shown that DMSO targeted cancer cells. Is it any wonder that the referee of the article stated:

    “In spite of my criticisms, there are some parts of this study which do interest me very much. The fact that the Haematoxylon [a color die, which allowed the researchers to see which cells absorbed the DMSO and haematoxylon] and D.M.S.O. solution had a particular affinity for neoplasms [i.e. cancerous cells], and did not stain other tissues in animals could be most significant.”

    Read More

    There is another website with several cases of bone cancer or metastasis treated with apricot seeds. I am not sure how much truth is in the stories but there are email addresses provided for the patients so you can contact them directly and ask them. Here:

    Apricot seeds/B17/Laetrile was considered by a serious cancer center before they started to ridicule it so there must be some healing power in it, I am pretty sure. The fact that any distributors/promoters are so heavily ostracized in the US indicates it too.

    Kind regards,

  14. Yes, that “serious cancer center” again turns out to be Sloan Kettering Memorial Cancer Center, told by Mercola:

    SK buried its related research but there are some more recent articles authored in Germany and other countries.

    Here are just a few of the more recent studies that substantiate Dr. Sugiura’s work:

    August 2014: In a new German study, amygdalin dose-dependently reduced growth and proliferation of bladder cancer12
    May 2013: Amygdalin inhibits renal fibrosis in chronic kidney disease; researchers conclude it is a “potent antifibrotic agent that may have therapeutic potential for patients with fibrotic kidney diseases”13
    February 2013: Amygdalin induces apoptosis in human cervical cancer cells; authors conclude it may offer a new therapeutic option for cervical cancer patients14
    August 2006: Amygdalin also induces apoptosis in human prostate cancer cells15
    February 2003: Amygdalin from Prunus persica seeds (peach pits) shows anti-tumor effects comparable to epigallocatechin gallate in green tea16

    1. Dear Helga,
      With all respect i write to you.
      Don’t trust everything written on cancertutor
      Also, apricots as seeds would have to be ingested something like 2kg / day for any terapeutic effect. *let’s be real here*
      The extract, iv etc. is extremely expensive, at least here where i live, and as i understand it…. even that is weak for cancer and not something someone would be able to sustain as treatment for very long due to financial reasons.
      It sounds to me that Diclofenac would be a more powefull against cancer

      Best wishes,

      1. I agree.

        Probably there is some truth in b17 properties but I have the feeling its being “oversold”, there are peole who keep advertising it, there are shiny webpages around it, price is high ( you can buy lots of stuff with more proof behind that cost 1% of laetrile’s price).

        I even hate the fact that advertising people call it a vitamin – while its not.

        eating apricot seeds was a great fun though when we were children. Some adults kept telling us not to eat more 10 per day, we never counted.

        1. i love apricot seeds, as a kid and now.
          I ate a lot of them, they didn’t even give me indigestion so for me in my personal opinion they are not poisonous at all.
          Tooth paste is more toxic than apricot seeds, so it seems to me.
          As far as them being anti-cancer, i seriously doubt it.
          It’s being promoted all around the internet that eating a few apricot seeds a day will make your terminal cancer go away rofl.
          Oh and don’t eat too many because your cancer could go away too fast lol.
          That hidden truth that nobody wants to expose, the forbidden cure FDA keeps away from those in suffering.
          Obviously a big stream of advertisement, a movement aimed at the desperate.
          The pure substance iv however “may” have “some” effect if any, Good or bad or neutral.
          i rather not spend thousands upon thousands of $ on something that may do absolutely nothing.

      2. Dear Alex,

        Naturally, I approach everything with a critical mind, that is why I cited a reviewer’s comment on a scientific manuscript submitted to a scientific journal. However, could you expand on your view as to why you think cancertutor is not to be trusted in particular? Do you have any bad experience with it or with DMSO?

        Re: apricot seeds, it in itself should not be expensive or difficult to find. Perhaps laetrile is oversold/hyped indeed. What makes you think that we would need to consume 2kg to make a difference? It would be nice in general if people didn’t make statements like this without at least some supporting evidence. That is what makes Daniel’s site unique, there is always an effort to support therapeutic suggestions with explanation/scientific or anecdotal evidence/or at least a plausible hypothesis.

        I know I myself find things sometimes that might not stand scrutiny in the long run but I always try to find and cite the source of the statements at least.

        ps. in case there was any evidence given in the youtube video, I have no time to watch them as I can read much faster than listen to people on youtube.

  15. There is another interesting substance, called ursolic acid:

    There are several recent scientific articles proving its anticancer effect, e.g.:
    “Ursolic acid exerts anti-cancer activity by suppressing vaccinia-related kinase 1-mediated damage repair in lung cancer cells

    Many mitotic kinases have been targeted for the development of anti-cancer drugs, and inhibitors of these kinases have been expected to perform well for cancer therapy. Efforts focused on selecting good targets and finding specific drugs to target are especially needed, largely due to the increased frequency of anti-cancer drugs used in the treatment of lung cancer. Vaccinia-related kinase 1 (VRK1) is a master regulator in lung adenocarcinoma and is considered a key molecule in the adaptive pathway, which mainly controls cell survival. We found that ursolic acid (UA) inhibits the catalytic activity of VRK1 via direct binding to the catalytic domain of VRK1. UA weakens surveillance mechanisms by blocking 53BP1 foci formation induced by VRK1 in lung cancer cells, and possesses synergistic anti-cancer effects with DNA damaging drugs. Taken together, UA can be a good anti-cancer agent for targeted therapy or combination therapy with DNA damaging drugs for lung cancer patients.”

    The good news is that ursolic acid is easy to find in plants, e.g. in the skin of apple, rosemary, basil, etc:

    You can also buy it as a supplement:

    1. Thanks a lot for your comments and help Helga

      I will take a good look on Ursolic acid , I wasn’t aware of it until now

      but regarding apricot seeds , I wonder if its better to take about 30 seed daily or to get laetrile as IV ?

      1. Hi Emad,

        I am rooting for your success at treating your mom. I didn’t know that you are in Libya and a medical student. Very interesting. We in Europe hear only sporadically about your country and usually only bad things. How is life there these days, I wonder?

        Re: ursolic acid, allegedly this is even better:
        For its source I recognize only rosemary in the list and there is this flower:

        Allegedly it is toxic when ingested in high amount. This brings me to my theory: quite often cancer is treated successfully with weak poisons. Like apricot seeds for example. While it is toxic for normal people, it might be less toxic for cancer patients whose cancer produces the enzyme that breaks it down in high amount. On the other hand, the opposite can be also true, namely healthy people’s detoxification system works better than that of cancer patients.

        Ah, sage too: It has tujone in it, which might be also toxic in high amounts, however it has a good anticancer profile as well.


        1. Hi Helga

          thank you for your concern

          unfortunately things are getting worse each day here in Libya , controlled by a bunch of criminals who have the power and the ability to make things better , but they only do every thing to make things worse

          God give me strength


          regarding Allegedly and ursolic acid , they are interesting and new to me , lot of things to about them , I will put them in my mind

          thank you so much

          Emad ^__^

          1. hey emad, offtopic, yes, sad for you guys, hope it will be better in your lifetime. our government in hungary is also a bunch of criminals (worst in eu)but of course different level. be strong.

      1. thank you dear Alex

        I saw the videos , interesting

        regarding laetrile I’m not sure if the oral version is worth trying like the IV version

        but the problem like you said that IV version is expensive

        regarding Oleander , this one Ergin used in the beginning , is it used as IV or oral ?

        and which are better ? and how about there prices ?

        I was aware about Oleander , but not that much

        but really I should take a very close look on it , it seems helpful to so many peoples

        1. Ergin may help more than me on that…..
          Personally i think it makes sense to first get your mother feeling better with adequate nutrition, detox, hydration. Too much treatment……
          Get her feeling better, relax a little…
          “Zoom out” as Daniel likes to say. More testing for other things, not just tumor markers. There are many treatments…
          But they won’t work if you go blind into them, you have to know more about your mother’s bio-chemistry, hormone activity, immune system etc etc etc.
          I personally believe that “modern medicine” is unaware of the full view. So a broader view is needed. Zoom out.
          See what caused the problem, fix what is wrong, help the body recover, do what can be done non-toxic, hope for the best.
          All these remedies will do nothing if the organs, glands, etc are not working in harmony, the mind, emotional situation is HIGHLY IMPORTANT!!!
          Sometimes a small gesture can help a lot.
          Chemo will work, but it wont do it completely, and the body can only take so much of it, same with the others.
          “The body is not deficient in chemotherapy you know”.
          So clearly we are missing something here aren’t we? I realized that after my mother’s surgery, i wish i did so earlyer.
          All this may sound like mambo coco jambo, i know… Mens Sana in Corpore Sano
          I’m curios to know what you think.
          I wish we were all together in the same room, we would then help each other so much.
          Many thanks,

          1. yes sometimes we need to be relaxed and regroup our thoughts so we can act better and take better decisions

            you said it all man thanks a lot

            I remembered something btw , I was about to use DCA with HCA + CA , but lost the road again after I read about possible interference between CA and DCA

            maybe I will take the risk and combine them all , but looks crazy decision , not well studied and against your opinion huh 😀

            1. I dont know everything. so maybe what you feel or think is better.
              Instincts were telling me, based on the science explained to me by Daniel, that DCA+CA, are not a good idea.
              But out of respect and being aware of how little i know about all of this, that i could be wrong, i decided to shut up, a small mistake….
              Sometimes it’s best to look stupid, ask stupid questions, you never know….
              1000 stupid questions 1 Genius question – Nobel Prize, etc etc etc. lol

        2. Instead of B17, Layetrile, Amigdalin, Apricot Seeds, i would go with a good old diclofenac, aspirin, paracetamol etc.
          They are 10XXXX times better, that’s how i feel. Waste of time, money, hope, energy etc.
          Maybe the IV version would do something….. something…. idk, not interested in throwing money at it. Did enough of that on other useless things already. Such as Graviola, Paw Paw
          They are all marketed as wonder miracle cures. “Don’t take too much, you may get rid of your cancer too fast, watch out!”
          Sometimes i hate this planet, no wonder the aliens aren’t coming to visit, we are not worth it. Primitives still valuing $ more than life. Pathetic.
          Anyway, Daniel want’s us to make our own choices, probably because he feels he doesn’t have all the answers. Maybe…
          I know deep down inside he thought about all this very very very good. But he’s trying to hint towards the best possible answers to our problems. So to Daniel’s time consuming pleasure, we should do our best to keep asking questions, one or more of them may be the right ones, that may lead to our personal right path.
          To stop asking questions is to stop looking for answers
          While the answer may not come, the question was addressed and a connection may be made later on.


          1. I totally agree with you

            and regarding diclofenac , I’m just worried about the long term side effects , what do you think ?

            its a good choice when also using DCA , I may consider it but not sure how long we can stay on it

            I really hope we can meet each other one day , I really hope that

            this blog is like our home 🙂

            1. What i can say is that my mother was taking diclofenac before diagnosis, relative high doses, 200mg/day i think, for about 6+ months
              She had existing heart problems, so if that’s not an issue maybe one could go higher.
              It’s also the thing that i believe has made the tumor stay in only one place while growing. the doctors were surprised that she didn’t have massive mets, They did see something but were uncertain…..
              Cancer cure? i think not….. Something that will help?! for sure!!! Risks? Always….
              May wanna check out simvastatin while you zoom out a bit from all the chemo rush.

            2. Thank you so much dear Alex

              I started to give my mother metformin , around 1.5 to 2 g / day

              maybe next time will add diclofenac and chloroquine

              the only long term side effects I’m worried about when using diclofenac is being hard on the stomach

              but I feel it can help when always I’m reading about it

              hope to always hear good news from you 🙂

            3. Start slow with metformin, you don’t want her feeling bad, migrenes. IF you get that, give her something sweet
              If you are worried about stomach problems, i believe disolving it prior to swallowing with food, may help.
              We alternate Diclofenac day, Aspirin day. Diclofenac Day, Aspirin Day but always with metformin
              Omeprazole also helps protect the digestive system
              I am sure we all have a lot to learn from each other.

              Mother is feeling good, we developed a rating system for pain, 0-10, she is at 1.5 she is not taking heavy pain killers on opium or morfeene etc. We check pain to see if things are getting bad or good, real time markers?!
              I know aspirin and diclofenac are pain killers but they would do little for pain compared to heavy drugs.
              So i hope/believe the lack of pain would indicate slowing down, stagnation, remission of the cancer.

              There’s plenty of stuff out here, try to build your defense then see if chemo is needed. eh?
              You have to make a fortress, all known vulnerabilities checked.

            4. Hi emad, you can buy diclo combined with a stomach protector, i dont remember the name but u Will find it. Less risk then..

            5. Hi Emad,

              I am not sure if your mom takes omega 3 but acc. to Daniel’s article there was a signif improvement of late-stage breast cancer patients by taking it: He suggests that all patients take it. Oh, I remember you said she takes Budwig but maybe not in a high dose. Daniel says some people take 15 grams per day.

            6. we used to take Budwig with good doses suggested by cancer turor , but my mother didn’t tolerate its taste easily and sometimes started to vomit it

              but I hope omega 3 capsules can be as good as flaxseed oil

              I keep wondering why there is no such thing like budwig diet but in capsules !?

              it should be helpful for the entire body in everyway

            7. Thanks a lot brother Pouya , this one could really help

              its really a very good thing to be able to have something like budwig in capsules

              hope you are doing good , we will talk soon 🙂

            8. Hi Emad,

              We make Budwig with added ingredients. We use a mixer and add green leaves, like spinach, arugula, etc. I also add, for taste, and health, parsley, sage, rosemary and thyme (really, but here is the Simon & Garfunkel song, called Scarborough Fair: with these 4 plants :-))

              Or you could also add fruits if your mom can take/tolerate that.


      1. yes they should be removed , but carefully

        i read in cancer totur that if the mercury amalgams not removed correctly , then probably it will make things worse and a lot of mercury will fall or be swallowed

        also what he said that it may cost around 10,000 dollars to remove them in the right way as he explained

        here in our country you may get infection easily for just a normal dental work like cleaning your teath !!

      1. cancertutor is exagerating a lot….. a lot…..
        A dentist (especially if made aware) with a little incentive, will do the job right for you and your mother, no need for 10.000$.
        The less mercury the better. 🙂
        The less toxins the better 🙂
        To be honest after all the chemo, i kinda feel mercury amalgams are the smaller problem to address at this time.
        If you and your mother wish to stop chemo, you have to detox, and detox and detox and detox and detox….. ………. ………. …….
        First there is the intoxication in the body to address, then there is the intoxication sources in the house etc.
        Don’t believe everything out there. 🙂


        1. I agree , and with that our first goal in our treatment plan is to find a better way to stop cancer other than high doses of chemo

          its not easy at all , hope we can somehow do it

  16. ”In a clinical pilot study with nine breast cancer patients, diazoxide was used at a dose of 200–300 mg per day [4]. For inclusion, maximal tolerated fasting glucose level was 110 mg/dL, and 180 mg/dL after an oral glucose load with 75 g. The best response was seen in a 60‐year‐old woman, who had glucose levels of only 56–105–115 mg/dL in the oral glucose load test. After progression of her cutaneous metastases during tamoxifen treatment, she was supplemented with 200 mg diazoxide per day and her fasting glucose levels rose to 90 mg/dL. Partial remission with this combination ended after 7 months when liver metastases were detected sonographically. Two months later, both medicaments were withdrawn because of rapidly growing cutaneous metastases and pleural effusion. Another 2 months later, the patient exhibited a rebound response of 4 months duration with the disappearance of pleural effusions, partial remission of the cutaneous metastases, and stable size of the liver metastases. In two additional patients with prior disease progress, diazoxide treatment resulted in stable disease of 8 (combined with tamoxifen) and 4 (monotherapy) months [4].”

  17. Tumor marker results today

    it shows a slight increase on ca15-3 , from 608 to 611

    but also I believe that the markers actually decreased , because we delayed the chemo 5 days , and the markers were progressing incredibly fast , so I think they become more higher than 608 before chemo

    I can see we stopped the progression , so this is good news for me

    but that bad news is : DCA will rest in peace , after using it for about 1.5 year , it lost its effect

    also the neuropathy become worse , so once I receive 3-BP and Sal , I will stop it , maybe will give it a shot before the chemo day only

    we used to have a better results in the past , now we almost have a stable disease only

    I hope to find a good results soon with my next strategy

    and by the way , nice to be here again , as I nearly got a heart attack because of the panic before I get the results

    thanks my dear Pouya you have been supporting me today , I really appreciate your existence, thank you so much

    also thank you Ergin for your emails and concern and continues help , I wish to get my hands on a strong protocol next weeks , so we can have a solution for both your mother and my mother , really wish the best for you

    Daniel , thank you my man

    the war become much harder but as much it become hard , I believe that time we could find the solution

    I will do my best not just to help my mother , but also to lead people to a much stronger protocols that can bring hope back to them, and of course with the help from God then finally with your help

    1. Hi Emad,

      Great to hear about the news! Actually, like someone said on Cancer Compass, you should not undervalue achieving stable disease. That is something amazing you had during all this time with the help of DCA. I would not throw away DCA so fast if I would be you, as long as it shows results. I would add Sal and only consider 3BP if I would see progression. But off course, you know better what you should do as you know and see all the details related to your mom, that others can not see.
      Again Emad, congratulations, as stable disease is a great results which as I understood chemo alone could not deliver in your case!

      Kind regards,

      1. thank you so much Daniel

        I will not throw away DCA just because it didn’t help as before , actually it still help as I know without DCA the cancer will progress so fast

        but the neuropathy is becoming worse

        we had a bad days in the past week , my mother suffered a bad muscle strain and extreme pain , and her legs became weaker

        and just 2 days later she saw a strong tremor in her hands which make her panic , and still she is having tremor these days , and I believe I should give a rest to her nerves before things get worse

        anyway , thank you so much for your support

        I forget also to thank our dear friend Jcancom who also supporting me these days , wish the best for all of you

  18. Dear all

    2 weeks later , CA15-3 was 611

    since that time , we did blood transfusion in the same day of the result , then only DCA for 2 weeks

    today, in another lab test , CA15-3 show high elevation to 1443

    also liver enzyme test is so much concerning me

    AST = 95
    ALT = 59
    GGT = 163
    ALP = 129
    Bilirubin is normal
    all the other tests are normal

    tomorrow the CT Scan and PET Scan results will come , i will share the results soon

    1. Hi Emad,

      Is this a jump as a result of a treatment effectiveness, or there was no treatment performed between 611 results and now at 1443 result. Also what is the LDH variation in this time?

      Kind regards,

      1. we did not have LDH test unfortunatly

        between the 2 test results we only did DCA + Procaine every third day

        no chemo , also 3-BP + Sal didn’t arrive yet

        1. Dear Emad,
          I hope it is because of dying cells.
          I am really sorry to hear that but first we have to wait for CT results,early yo talk.
          may be ascid is the cause of big rise.%150 in 2 weeks!As i see % 300 in 1 month.The cause was ascid because of hypothyroidism not tumors.
          Liver also can cause ascid and rise in markers.
          We will be always near you.
          Kind Regards

          1. Hi Ergin,

            Can you please shortly update us on the experience of the doctor in turkey with the T4 depletion strategy? You mentioned on private that he saw some positive results? Thanks in advance.

            Kind regards,

            1. Hi Daniel,
              I ll write the details tonight about T4 strategy inorder to help people.
              But while Emad is dealing with a serious problem,i didnt want to write good news about my mother.
              Kind Regards

            2. I very much understand Ergin. I apologize for asking. Just report whenever you think is suitable. Kind regards, Daniel

            3. Dear Daniel,You are right,people has to know what i know,and the time is not to sit and cry.We have to be brave.If i know an effective treatment,i have to write it.This is the right time.May be also Emad will also look at it.
              Kind Regards

        2. Hi Emad,

          Yes, let’s hope that such a jump in such a short time (2 weeks I understand) could only be explained by tumor lysis or as Ergin explained. We wish you the best outcome possible from the scan results, Emad.

          Kind regards,

          1. Dear Daniel , dear Ergin

            I’m sorry as I so wanted to celebrate for the good news from Ergin and his great success with his latest strategy

            I just received the CT Scan results , not so good

            in French :-
            apparition par rapport au dernier scanner de multiples masses hepatiques interessant tout les segments du foie droit , la plus volumineuse au niveau du segment VII et VI mesurant 10 x 5cm responsables de contours bosseles du foie .
            ll s’y associe egalementdeux autres masses du segment VI de 3 et 1.9 cm

            trois masses des segment IV et VIII mesurant 2.2 et 2.7 cm

            masse de la partie inferiere du segment IV mesurant 2.4 cm

            after translation to English :-

            Appearance in relation to the last scanner of multiple hepatic masses affecting all the segments of the right liver, the most voluminous in the segment VII and VI measuring 10 x 5cm responsible for contours bosseles of the liver.
            It is also associated with other masses of segment VI of 3 and 1.9 cm

            Three masses of segments IV and VIII measuring 2.2 and 2.7 cm

            Mass of the inferior part of segment IV measuring 2.4 cm

            I don’t know what to say

            1. I am so sorry to hear that Emad. Is there any chance you could afford to go for Trans Arterial Chemo Embolization?

            2. I want to ask Meech about how much it cost her for each TACE session

              or if you know the cost please let me know , also if there is an average price between doctors , because with prof Vogl it looks more expensive than the others

            3. Hi Emad,

              Typical cost is 4000 euro/intervention and he suggests about 4 interventions for one organ. But others are doing more interventions. We also did a few, and I was very positively impressed by him.
              I’ve heard of rare cases where he made a discount going to 3000. You would probably have to explain in advance the very difficult financial situation. I only know his prices but maybe others visitors would know TACE prices from other doctors.

              Kind regards,

            4. Hi Emad,I will also ask here tomorrow.I have a room for you and mom at home brother.

            5. Thank you so much Ergin

              both you and Daniel are always helpful so much , me and my family we love you all


              the oncologist will see what she can offer tomorrow morning , i can’t relay on her help of course

              and because i think that the liver cannot wait more than that , maybe this month we will visit prof Vogl

              we have enough for the first session , also we will need more sessions after few months

              we have a chance to get some help from our government , if we succeed to have the proper help from them it will then be much easier to continue until we treat the liver properly

              so for now we need to move fast , i don’t want to be ruined by something like ascites , hope we can manage things quickly

              i will share more things in the coming days

              thank you all 🙂

            6. Hi Emad,

              Your msg is so kind even now when having to deal with these difficult news. We all very much appreciate you Emad and hope for the best of your mom. We pray things will get better again. You always succeeded to fin a way to get things under control. Now, you will do that again.

              In order for you to have the complete story I have regarding TACE, I must say that although personally we did not experienced serious complications and I haven heard in general about major complications, there is one specific case I heard of, where a lady has passed away about a week after a TACE intervention. That was not her first TACE and it is not clear if that was a result of the fact that they were using systemic chemo in parallel to the TACE intervention which could be too much, but her immune system has collapsed suddenly after about a week, although the days before things were getting better and better. With this example, although the unfortunate event may not be related to TACE, the point I want to make is that anything we do comes with risks and we have to be aware that those are there even if statistically the risks are reduced.

              Kind regards,

            7. Thank you so much Daniel , i will do my best to recontrol things around

              yes I know all the risks from doing TACE , and before that i have learned the risks from using Sal and now 3-BP

              everything comes with a serious risk , and for me , it worth all the risks now

              the biggest ever risk is to not take any risk , and death from a treatment is a lovely death compared to death because of cancer

              that’s my own opinion and i believe my family have the same opinion , its always our responsibility , and we have a goal and we must do the better thing in time

              best wishes

            8. When I went, we used quite an aggressive TACE regimen.

              I would receive one session of TACE to the liver on Monday, then receive a second session two days later. We did this every single time I did TACE.

              I don’t know if this is the usual treatment schedule, as I have heard that it was only one session per month, but for me we did two.

              My side effects were: low grade fever (from the quick tumour destruction most likely), and some GI issues (nausea, diarrhea).

              Once, I also had quite a large hematoma, which was caused probably by picking up a baby too soon after the incision into the femoral artery was made. The pain from this lasted about a week to a week and a half.

              All in all, my side effects weren’t serious, and they didn’t last longer than a couple of days. Most times, I received a TACE session on Monday, one on Wednesday, and was on a plane home on Thursday.

            9. thank you so much for your valuable comment

              I asked Prof Vogl and he mentioned 3 to 4 monthly courses , so does he mean that one TACE session maybe every 3 months ?

              or he means 3 to 4 TACE sessions ?

              for us probably we can’t do TACE more than once every 2 or 3 months , so I hope it could remain effective for this period of time

              how is your condition now btw ? do you have a problems related to the bones or still the liver only like my mother

              wish you the best Meech I hope one day soon you get cured from this disease 🙂

            10. Dear Emad,

              Just one addition to Meech’s valuable response: I expect what prof Voghl meant was one intervention per month during 3-4 months. That means a total of about 4 interventions to see if there is response or not. (Off course response could be from the first TACE or may not be even after 4 TACEs, depending on the tumor response to the specific used chemo.) This sounds like his typical suggestion, but patients can always decide to increase or decrease the frequency from monthly interventions as suggested.

              Kind regards,

    1. Thank you always J for your care and kind feeling

      we will do our best to re control things again

      today the oncologist did see our results , she was worried about the progression that happened

      she did contact some other specialist and then decided to change the chemo to another new combination

      we used to take Carboplatin + Gemzar , and the both are heavy on the bone marrow which always lowering the blood counts and then delay the chemo and require blood transfusion

      the new combination she suggested is (Cyclophosphamide 1g + 5-FU 1g + Methotrexate) every 3 weeks

      also like always , the bone lesions are still stable more than a year ago

      I don’t know why whenever we talk to a conventional doctor they told us that TACE is not required !!!

      is this because TACE is not an approved method for breast cancer or what ? I really don’t know how they think

      but anyway we decided to do TACE as quickly as possible , the liver masses must stay small like before , my biggest ever nightmare is liver cirrhosis or ascites , and I can’t rest peacefully until there is no more risk of such things

      I will continue to share things all the time

      wish the best for me and all of you brothers

      1. Dear Emad.
        I am filled with pain over many personal reasons and it kills me to hear things aren’t going well for you and your mother despite all the huge sustained efforts.
        I wish i could do more than just write a message.
        Perhaps there’s something to be done still.
        Local Hyperthermia, DCA+ the rest
        I always wonder why you didn’t go for oral administration of DCA, daily, why no vitamin B1, why …? The small things like diclofenac, aspirin, metformin, they all have their major contribution.
        From reading your story i gather DCA has been more effective than chemo all together. This may be wrong.
        Maybe this LDN, and T4 depletion, coupled with diet. GcMAF, nutritional elements meant to sustain health.
        I am sorry i am saying maybe, it’s all i got. I’m still very much interested in 3bp and Sal myself, for my mom.
        Thank you very much,
        Let me know,

        1. Hi Alex

          the capabilities here in Libya are so weak , no hyperthermia available , they even don’t know about such thing , I’m still doing DCA IVs , but its not helping like before

          what I know is that IV DCA is better than oral , I’m still giving my mother B vitamins , I know the potential of NSAIDs but I’m not sure if its okay to use them continuously , also my mother is taking metformin now for over a month , 2g daily

          LDN is not available I wanted to use it but I’m waiting for 3-BP + Sal to arrive , T4 depletion is a good strategy that I was thinking to use it for a while , but first I want to use the up coming strategy , also it needs time to work

          GcMAF is not a good option when chemo is still used , the immune system is weak , I have to wait until that day come when my mother could finally stay good without chemo

          but as I said before , the liver masses cannot wait , we have no fast option other than TACE , and the first session should be done this month , we have the ability to cover the first session , but for the others we may have some help from our government

          also from our poor government we have a chance to be treated in Poland , I don’t know if anyone have any information about good clinics there !?

          and btw , thank you so much for your concern and feeling dear Alex

          I wish your mother is feeling good , how is her now ?

          1. hi Emad

            good luck with anything you decide to go for… hyperthermia i am considering currently.

            how come this polish opportunity? is there an agreement between the governments?

            1. No agreements at all

              but one of the governments which has some power actually are still having the ability to give some cancer patients an opportunity to have a treatment in Poland , I don’t know why Poland exactly

              but still it needs some time to complete the regulations required for having this help, I hope the clinic they are sending us to it have more than just the nasty chemo

          2. Hi Emad,

            I couldn’t reply to your other comment there so I’ll reply here.

            When he says “three to four monthly sessions”, he likely means 3-4 in one month. I’m not 100% on how effective one session every three months would be; I think you should email him. He answers emails within a few minutes usually.

            About the procedure: it’s mostly painless but a bit uncomfortable. You may feel a bit of pain first with the local anesthetic needle, then with the initial puncture into the artery, which doesn’t last a long time (a few seconds), and then some discomfort internally as he passes the catheter through, but it’s nothing serious. Each procedure took about 10-15 minutes, but there are MRIs beforehand, then resting in bed for three hours afterwards, then a quick CT scan without contrast immediately after the three hours. Then you have a consult with Prof. Vogl to talk about the procedure, which lasts about two minutes as he doesn’t speak too much. All in all, you’re probably in the hospital for 5-6 hours, and are then free to go.

            My condition is good, from a subjective point of view. I don’t feel pain, I’m not tired from the cancer, I work out, go out, etc. It’s hard to tell that I even have it, apart from having to have a nephrostomy tube, and some palpable tumours. However, CT scans tell a different story. I have it in all six lobes of my lungs, multiple lesions in my liver, at least one bone tumour, and I can’t even count how many lymph nodes. Every CT scan I do, I have new spots of metastasis. However, for whatever reason, once the tumours do seed somewhere, they don’t seem to grow very fast.

            Thanks Emad; I hope the same for your mother 🙂

            1. damn cancer, Meech. I cheer for you.

              I have no visible met and currently normal markers but i feel worse than you (constant back pain, neuro problems). I will have a brain MRI soon after 4 negative spinal MRIs.

              i fear i have leptomeningeal carcinomatosis – the only thing worse than a brain tumor.

              what about using 3-bp in your case?

            2. See if the treatments you did can leave permanent damage to those systems. Use of platinum based chemotherapy can lead to neuropathy. Radiation to those areas can also lead to more long-term problems when scar tissue builds up in the area. Hopefully, as debilitating as it may be, your issues are iatrogenic and not pathological.

              I haven’t actually really considered 3BP and it’s mainly due to the knowledge needed in terms of preparation and administration, as well as not hearing enough positive case reports to warrant such a huge commitment.

              There is a local clinic here offering the treatment (or at least there was), but when I called to ask about it, they seemed much more concerned with their more “promising” therapy (which I believe was insulin potentiated chemo), than with what they seemed to consider a more minor therapy in 3BP. Which led me to believe that either they were concerned with a profit motive, or they genuinely weren’t seeing any sort of miraculous response with 3BP.

            3. I had lots of cisplatin (worked big time for my only visible tumor and did not have typical side effects other than hair loss) so oncologist blamed everything on it at first.

              After round 1 (september) i developed back pain and from November I started having mild but clear CNS symptoms (not peripherial neuropathy which is normal with Cisplatin). Some of these remained as they started out – some of these are stronger now.

              Lets hope im one in a million who reacts to cisplatin like this but im realistic (and hence pessimistic) – i think its cancer.

            4. Thank you Meech , your comment is so helpful , I will always wish the best

              I have a little question , did prof Vogl asked you to give him a CD (latest CT scan results) before starting on TACE ?

              if yes , then did you uploaded the data in the CD then give him the download link ?

              or you did transfer (ship) the physical CD to his location ?

              I know its confusing but I don’t understand why he can’t just download the data I gave him

            5. He did ask for the images and some reports. I shipped the CD to his physical location, these CT scan files tend to be too large to send via email.

            6. Oh my !

              I thought we can visit him after 10 days , but sending the CD it self can take a week or more

              like we are living in 199x , they cant just download the files or am I wrong ?

            7. Hi Emad,

              I do not think it is related to being able to access your online file as they are one of the largest hospital in Germany, but it is possible they have own info security rules.

              You can also suggest to go there and decide on the spot what to do, if you explain you would like to act fast. They will anyway perform a scan in the morning prior to the intervention (and another one after, in the afternoon, to check if everything is fine). The risk in this case could be that after investigation of the scans, prof Vogl will think he should not go forward with the intervention. However, I expect this risk is very limited given that I know they perform interventions even in the most complex cases.

              Kind regards,

            8. Thanks Daniel for making things clear , we found a friend in Germany who can help by downloading the soft copy and burning it on a CD to send it to prof Vogl quickly

              I asked prof Vogl to provide the address to send the CD right to it, but he is not responding today , maybe because its the weekend

              anyone still remember the address ?

            9. Hi Emad,

              You are welcome. The address of prof. Vogl is easy to find on the web. Here it is:

              Univ prof dr thomas j Vogl
              Dpt of Radiology
              University of frankfurt
              TheodorsternkAi 7
              60590 frankfurt

              Kind regards,

      1. Hi Emad,

        Phlorizin is very special.There is a term called phlorizination in science world.
        You use it once before chemo,perfect,i like it.But not oral and you know how hard to use,a very long iv infusions,control control.
        (But 12-24 hrs is enough)Probably using it with 3BP makes the treatment very strong.In phlorizin patent they use similar.
        Others are oral drugs and after chronic use of drugs,i think you reach your goal after days or weeks like all other treatments.At the end there is no glucose inside the tumor which expresses SGLT.It depends on us how we use it.What dosage?Which type?
        I think we have to talk on it and combinations with others.
        Emad,When i saw only 113 people is registered but nearly 1 million enterance ,first i highly demoralised.Than i began to look from another side of view.People here are really different than the other thousands.We are learning everyday by Daniles and registered friends helps.It is not clear that we are always doing right treatments,but at least we are trying something for us and people.We are not secreting knowledge.If we were 1000 people here,it would be the biggest clinical trial.
        Now we are talking on 10 people.It is impossible to talk about treatments worked or not worked.
        I have an idea to write mails about SGLT inhibitors to experts and write here.What do you think?

        Kind Regards

        1. Hey Ergin,

          I am looking forward to see the topic on Dapagliflozin that you promised you are going to start. You can start by sharing with us a consolidation of your research findings that convince you is the way to go. Or you need to investigate the subject more?

          Kind regards,

          1. Dear Daniel,
            I am very sorry that i wrote your name wrongly.

            I am working on it.And have to talk wtih endocrinologist on tuesday.
            When and why do they give it to diabetic patients,any side-effects?
            Can we use metformin+dapagliflozin together?Max Dosage?
            Is there any iv form?Can we use it with diuretics or beta-blockers?With T3?I hope i get the answers but not sure.
            Its effect on cancer is clear for me.But the others is more important for now.
            Because i am only afraiding of hypersensivity to chemo.After 2 big reactions.And still couldnt find the answer.
            I will write the post on thursday or friday after coming from chemo course if it is suitable for you also.
            Kind Regards

        2. I will consider it next after Sal + 3-BP or maybe I will add it to increase effectiveness

          but Dapagliflozin it self I think its not available here in Libya

          its worth a try

    1. Hi Sirsna,
      Daniel found that article before,this article really downs my motivation.In some of its sentences it says,glucose deprivation is not enough.
      Yes we know that and we want to use glucose inhibition for enhancement of treatments and slowing cancer and in some cases it kils cancer.What i learned from months is not to trust to all papers.There are some derivatives of SGLT inhibitors and i like them all.I found Only Dapagliflozin in pharmacies here,
      But Canagliflozin looks better.
      Daniel has already created a perfect post about phlorizin(SGLT1+SGLT2)but no one is interested.
      So i found a way to attract peoples attention about SGLT inhibitors.A photo that shows there is no glucose inside the tumor after dapagliflozin.Because reading is too hard for people.They already have lots of problems,they need a clear explanation to begin treatments.And there are a few articles about them.Thats why we always need Daniel’s help.
      His posts are really a summary of cancer treatment world.
      But you are the first people interested and searched for SGLT inhibitors.May i ask your illness if it is not private?
      Kind Regards

      1. Hi Ergin,
        i believe the disinterest arises from the circumstance that most people can’t IV themselves and dont have open minded doctors. in my country doctors strictly rely on protocols – i am surprised to see that turkey is more liberal in this aspect.

  19. Here is a nice article about canagiflozin:
    “The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration” Oops, I may be citing the same article that Sirsna already did, sorry. But it is interesting because it also further elaborates on the mitochondria – glycolysis conundrum, namely, that mitochondria are quite functional in cancer cells.

  20. New update

    today , my mother did her first TACE with prof Vogl in Germany

    both my parents are there , I’m still here in Libya

    the procedure didn’t take more than 10 minutes , there was a lot of patients there from all over the world

    my mother is feeling good , prof Vogl said that we made it to TACE in the best time , and glad we didn’t come late

    I wonder if the tumor did change since the last systemic chemo , i hope the systemic chemo did some positive effect

    also prof Vogl said that we can continue systemic chemo in time (May 31) , in his opinion its not very aggressive

    and he said that we should do the next TACE after 4 to 6 weeks , or 8 weeks maximum

    also 3 days ago we received Sal + 3-BP , I’m planning to use them after my mother return back probably on Friday

    that’s all we have until now , i will continue to share everything in time , wish the best for all of you 🙂

    1. Great to here everything went well. We were also there sometime in 2015 and in 2016 and its impressive to see how many interventions can prof Vogl handle in a day. Take care with using too much chemo Emad. As I mentioned, I know someone who used both TACE and some other chemo in parallel and there was a sudden failure of immune cell production which unfortunately was lethal. You should inform your doctor at home about TACE and if it makes sense to reduce the dose of the IV.
      Regarding the status now at the intervention, there are scans performed prior to the intervention that you should receive at home – letters and CDs with indications on the size of the tumor. All the best!

      1. Thank you so much Daniel you are always in help for our family

        yes we will tell our doctor here that we did TACE , we have the full report about TACE with all the chemos and doses that has been used , and the doctor may delay the next cycle or reduce the dose

        also yes my mother did perform a scan before the intervention , I will wait until Thursday to read about what did happen after the systemic chemo done previously

        but also not sure if one systemic chemo cycle can immediately change the tumor size , its not like TACE which is directly hit the tumor

        anyway , things are fine for now , wish a happy life for you

      1. thank you dear Alex , my best wishes also for you and your dear mother and family to always stay healthy and happy

        the total cost for 1 intervention including scans , tests , chemo drugs , all is about 3900 euro

        how things are going with you ?

        1. Thank you very much.
          wow at that cost. 🙁
          My mother is having pain…. however it goes away with diclofenac, no problem.
          The pain appears to be caused by treatment. Diclofenac did nothing in the past with regards to pain so this is new.
          Neuropathy just occurred today. This would confirm that oral treatment works with regards to absorption.
          Took almost a month for this to occur. Markers grew but it would seem they did so at about 50% slower.
          We’re getting a scan done soon and the much awaited story will also be available here soon after i guess.
          Best wishes there, good luck.
          Thank you!

          1. yes the cost is high , our only chance to continue TACE is to have a help from our government which is somehow possible but also hard

            as I said before , my mother did also felt pain after DCA for days , she felt pain in her bones , also she was taking DCA with chemo at that time , and the bone mets did shrink and become very small , and since that time the bone mets didn’t change and become stable for more than a year , and it still stable until now

            I hope to hear a very good news after the scan results , I’m sure that time will come when you feel happy

            kind regards

  21. These 2 images are from the latest scans done in Germany , I don’t know if its from MRI or CT Scan , the liver tumors are visible and clear , I can’t know if its bigger from the last scan done 2 weeks ago or its smaller

    but I have a good feeling that we can make things better soon

    the incoming days I will do my first 3-BP + Sal treatment , its time for having a new road

    I wish the best for all of you my friends just like I hope the best for my self 🙂

    1. they do MRI before , then CT Scan after

      I don’t know if the images are from MRI or CT Scan but it doesn’t really matter , the tumor will not change at all in few hours nor in days

      next TACE session they will do MRI and CT Scan again so at that time they will know what did happen with the tumors

      my mother felt nauseated for 2 days after the procedure , nothing else , she is fine now

      thank you for your concern Helga

      I wish for you a long happy healthy life 🙂

      1. Huge problems there saw the photos. Truly sorry, very bad.
        Still i hope in your plans you also incorporate organ support elements. Specially those organs that were affected or are affected by the treatments / tumors.
        Take care,

            1. I put a comment but an error happened so I have to type it again

              I don’t know if I’m making mistake and if I’m thinking in the right way , but I have some fear of using supplements that could protect the liver , fear that it may protect cancer as well

              maybe I’m taking it wrong , but also I feel the best way to protect the liver is to eliminate liver tumors fast

              we will do our best to make things better

              I hope your dear mother is fine these days , I will pray to hear a good news from you soon

            2. Thank you i hope for the same in your case.
              The neuropathy got worse, i am in doubt about Vitamin B1, i don’t know how to find out if that would help or worsen the situation in my mom’s case.
              I can confirm it works better with coffee, DCA i mean. (as in, there is more pain when coffee is drank)
              Pain is still there, lymph node is larger and larger…. don’t know exactly what to believe but i am trying to be optimistic.
              I guess we’ll find out soon.
              Take care, A great weekend to you and our friends

            3. can you please share the dose of DCA and B1 you give to your mother ?

              also the other signs like pain and lymph nodes getting larger may not be a sign of disease progression , there is a lot of things that may cause the same thing , so don’t just put in your mind that cancer is progressing

              you can’t just think only of the worst scenarios , you need to feel optimistic

              wish you always the best dear Alex

            4. 2000mg / day for DCA, but taking a break to lower neuropathy.
              No B1 because of uncertainty. (some expression i forgot the name of)…… kill or boost.
              We try our best to be optimistic.

            5. i don’t know the weight compared to the dose , but its some how near the high dose

              not using B1 will help cause neuropathy that’s what i know , I’m always giving it and with high doses , nearly 700mg/kg of B1 every day

            6. Dear Alex,
              I just read that inositol, a cancer-fighting molecule is also good at treating neuropathy! I hope you can look into this and find out more. My internet bytes are running out for now but will be back tomorrow. I hope the best for your mom!

              My mother may also suffer from cancer. She feels extremely weak after every meal. Today I prepared her a drink from citric acid and goji berries I ground with coffee grinder plus dried grapefruit pectin, which I also ground. She felt a lot better after drinking it! Goji berries are known to have a strong immune system supporting function and it is a very pleasant tasting drink, I recommend it to you and everyone. Plus, quite cheap and sold at health stores.


        1. my mother did get back 3 days ago , TACE is a small procedure that only took 10 minutes to finish

          everything is fine , they determine the effect until the next procedure which should be 4 weeks later

          at that time they will do MRI again so they can compare it with the previous one

          for now we will continue on systemic chemo like always , maybe in the next week , and until that i will do Sal + 3-BP

          aren’t there any new results about your mother ? hope to hear always good news

  22. Regarding blood counts (CBC) for my mother :

    after 1 week of doing systemic chemo (CMF) , we did CBC test

    WBC : 4.5
    HB : 10.3
    Plat : 145

    then she did her first TACE session (chemotherapy used is Mitomycin C and Cisplatin)

    after 2 weeks of TACE + few shots 3-BP + Sal , we did CBC test and it shows some decrease in counts

    WBC : 4.2
    HB : 9.7
    Plat : 52

    I’m somehow confused , what is most likely the cause of this ?

    is it the systemic chemo cause this even when the first week all the counts were in range ?
    or TACE may cause this ?
    or 3-BP + Sal may help cause this ?

    1. Dear Emad,
      I wish i knew the answer.But your work is wonderful,awsome.
      I wonder after 3-BP did you see any side effect?Did you look for blood glucose also?

      1. No I didn’t look for the blood glucose

        also I can’t notice any side effects , I’m giving her 160mg as IV , and doing my best to let it stable

        my protocol now is less aggressive

        day 1 : 3-BP
        day 2 : nothing
        day 3 : 3-BP
        day4 : nothing
        day5 : Salinomycin
        day6: nothing

        also when chemo is applied , I’m giving my mother some rest from 3-BP and Sal

        also I stopped giving her DCA completely , she hate it because of neuropathy in her legs , even when she know that chemo is the main cause of neuropathy but she refused to take DCA

        maybe next month she will do another TACE , if the results were good , then I will stay with my current protocol

        if the results is not that good , then I will be more aggressive in using 3-BP and Sal

        that’s my plan for now

        1. Thanks Emad for your answer.I will need your help on how to prepare phlorizin and 3BP.
          I only could talk with dr for 1 minutes this week.He said i will not take responsibility with preparing and using phlorizin.
          But he will use if we can formulate it.Do you know how to sterilize.The products comes from sigma etc are not steril i think.

          1. Hi Ergin

            I don’t have that much information on how to prepare phlorizin , I think its documented in the article in this blog

            also for 3-BP I’m only doing like Daniel mentioned in the 3-BP article , mix it with sterile water until no powder is visible at all , then pull all the 3-BP solution to the syringe

            now the syringe contains the 3-BP solution which is may not be sterile

            throw the needle if its used , mount the 0.2 um sterile filter on the syringe , then place a new needle on the other side of the filter , this way we can push the solution inside the NaCl bag , and the solution will go through the filter

            the syringe and needles are in every pharmacy , the 0.2 um filter can be easily found on , I think Daniel did share the same information with a link to on where to get the filter

            phlorizin should not be more complicated

  23. I have a news that is not good , and its not related to the treatment effectiveness

    looks like our chance to get a visa to Germany is very difficult this time

    even when we managed to have a financial help from the government , the visa is a big problem that may stop us from continue the other TACE sessions

    so frustrating this annoying world is crazy

      1. Sadly its not schengen visa , so it can be only for Romania

        I’m interested to go there but only to meet friends like you and Daniel not for treatment 🙂

        1. Hi Emad, I am a Romanian but I live in a Schengen state. I never did this before, and don’t know how it works but I may be able to invite you/your mom here? Let me know if this is relevant to you and if you have any idea what I would need to do for that. Kind regards, Daniel

          1. Thank you Daniel you always helping

            we will keep this as the final choice, if all the others fail

            but for now we have some choices that we can and must try first

            best wishes to you 🙂

  24. Hi Emad,

    couldn’t you get a supporting letter from your doctor in Germany to get a visa? What an upside-down world/country (Germany) where they took in a million migrants without any background checks but not you, a law-abiding, educated person with medical needs! Let us know if we can help to write supporting letters. After all, even the bureaucrats are human beings…


  25. We still didn’t do any systemic chemo after TACE done 3 weeks ago

    the platelets levels are still very low , also WBC dropped a little bit more !!

    when I read some articles about TACE , they talk about chemo is being stuck on liver region for about a month

    I don’t know if the chemo is still there and working which is causing a slight drop on blood counts but I can’t understand what is the reason

    the only thing I’m doing now for 2 weeks is giving 3-BP and Sal , my mother feels like they are the cause of this
    I can’t say no or yes

    I sent a message to prof Vogl , still waiting for response regarding this issue

    anyone have any idea about side effects like this happening after TACE or Sal or 3-BP ?

    1. Hi Emad, first off course for anyone things can be different and there is no statistics to say if you could relate any of the events you mentioned with drop of WBC or platelets. In our case, there was no drop in platelets or WBC that we could associate with the use of Sal or 3BP. I am not sure about TACE. I will have to check the blood results when I get home.
      Note that the drop can also be a side effect of the tumor itself. I would not expect the chemo is stuck for such a long time at the liver – the embolization substance should be dissolved relatively fast. When the drop in WBC started? At the time of TACE, before or after that? Were WBC and platelets at the right level prior to that, with no specific trend that could be observed?
      Kind regards, Daniel

      1. I know this may not look like an important thing to talk about , but in reality , this problem is what cause all our work to go out of control

        first of all , my mother used to have low blood counts always after every cycle of Gemzar + Carboplatin , the both are so hard on bone marrow , so the oncologist changed to CMF (cyclophosphamide + methotrexate + 5FU) , and she said it will not cause the blood counts to drop like Gemzar + Carboplatin

        usually the blood counts will improve after 1 – 2 weeks

        in May-9
        WBC : 4.0
        HB : 10.2
        Platelets : 140

        in May-10
        First cycle of CMF (systemic chemo)

        in May-17
        WBC : 4.5
        HB : 10.3
        Platelets : 140

        in May-22
        first TACE session (Cisplatin + Mitomycin C)

        in June-6
        WBC : 4.0
        HB : 9.7
        Platelets : 52

        in June-13
        WBC : 3.5
        HB : 10.1
        Platelets : 58

        I did contact prof Vogl about this last night and I received this message :

        Thanks dont worry it will improve
        The chemo is slowly deactivated by the cells in the liver

        Yours tv

        we can’t have any conclusion about what is the real cause , but we can only guess , and so we can know the quality of our strategy

        Kind regards

          1. WBC : 6.6
            HB : 11
            Platelets : 71

            its rising but still platelets is not enough , so the chemo will be delayed for another week

            because of that I’m now giving 3-BP + Sal more , 2 days on , one day off

            alternating between them

            I can even go more aggressive on using them but not for now

            we are doing our best to have the next TACE session after 3 weeks , until that I hope everything will be good

            thanks for your concern and help Daniel 🙂

            1. Emad, have you seen any tumor response to 3- bp?
              Are you checking the markers frequently?

              With 3-bp there should be a fast response. It is important to know whether it is helping or not.

            2. I know its important but we are not doing tumor marker test for now , maybe after 2 weeks we will do MRI

              but if there is a positive result we cannot know if its due to TACE or 3-BP or systemic chemo , we are doing a lot of things and its hard to know what is really working

              and also we are giving our self some mental rest from tumor marker test , its always my worst day in my life so its good to take some rest from it until the next MRI

              but generally my mother is feeling better with 3-BP and Sal , but I can’t decide anything based on feelings

              I will make sure to track the 3-BP effect as soon as we do the MRI , hope things get better

      1. Yes its very easy to manage WBC with this injection , we have it and its always doing the job

        but sadly there is no such injection for platelets which is our problem for now , it will take time to improve

        do you have any idea on the best way to manage this ?

    1. No I don’t know about this

      I read about it just now after your comment , it looks helpful

      I will give it to my mother and it may help

      Thanks a lot W 🙂

  26. An article about antibiotics,its effect is not only infection dependent :

    For example, in lung cancers, azithromycin significantly increased 1-year patient survival from 45% to 75%, an ~1.7-fold increase [26]. Interestingly, it was noted that even lymphoma patients that were “bacteria-free” benefited from only a 3-week course of doxycycline therapy, and showed complete remission of the disease [27]. These results suggest that the antibiotic’s therapeutic effects were actually infection-independent.

  27. a very small update

    after 1 month of TACE , the blood counts fall down but its improving now and its good

    also my mother is feeling stronger and able to do her normal activity just like any normal woman in her age (age 51)

    maybe because its been a while since her last systemic chemo

    but what is concerning me and make me feel uncomfortable that she is feeling nauseated these days

    she used to feel nauseated when she is on chemo , but these days she is not on chemo so why is that ?

    is it a bad sign of liver tumor becoming worse ?

    feeling nauseated is one of the symptoms of liver tumor becoming more advanced but there is a lot more symptoms like (feeling weak , pain , weight loss and more) and my mother only feels nauseated but nothing else

    its weird , I hope its not because of cancer , but what else it could be

    1. Hi Emad,
      Please search for some stomach problems like ulser or bleeding etc.
      Anemia causes also nausea.May be she needs hospitalisation.Sorry for giving a negative feeling but this makes you feel better.
      Kind Regards

  28. Emad, a suggestion: ferumoxytol. It is FDA approved for another indication so could go off label.
    A phase 3 trail noted below has already been done that included cancer patients, though no mention appears to be made
    about any anti-cancer effects. Another article below talks of how applying a magnet to the skin of mice increased the
    response with another magnetic cancer treatment. Best Wishes.

    1. This is interesting and worth trying as its very easy to apply

      I thought iron may feed cancer but these studies suggest it may lead to immune response against cancer

      I will add it when i make sure that our strategy now is not enough

      thank you always Jcancom

      also best wishes to you

    1. I wonder why there is not that much statistics on using them with animals , it shouldn’t be that hard to do such test

      they are promising and accessible but don’t have much attention

      hope to see more news about them soon

      of course its helpful suggestion like always 🙂

        1. Ergin, the ferumoxytol is a nanoparticle formulation of iron.
          It is confusing, though different forms of iron likely have different clinical effects.

        2. To me, giving Iron to a cancer patient is like giving glucose. That is risky as they may support the tumors as well. Given that we have so many other treatment options with potential and less risks, I would use Iron only if that will address a higher or shorter term risk compared to cancer. But not as an anti cancer treatment. In other words, I would use Iron if that is meant to improve e.g. hemoglobine in a patient who is at risk on short term due to very low hemo. Even if this may support tumors as well.

          With glucose is the same. There are ideas to use Glucose as a cancer treatment. If given in high dose on short term, that may be absorbed by the tumor and as a result lead to acidifying the tumor and hopefully tumor death. Although that sounds interesting from a scientific point of view, I would never apply that on a patient since we do not know if the acidity will be that high to kill the tumor, but we know for sure we will feed tumors.

            1. Hi W,

              I know this is an approach considered in Arte treatments (I think I mentioned that in my post too) but even in that case, I am not sure I would use it. In the end, if Arte reaches the tumor cells, there is enough Iron to interact with, as cancer cells stand out in terms of its storage. So, it may be good to combine Arte with Iron from a theoretical point of view but the risk is too high if Arte doesn’t get there, and this in turn doesn’t give me a good feeling about the use of Iron even when combined with Arte treatment. Anyway, this is just my feeling.

              Btw W, I remember you proposed to write a post on re purposed drugs. I apologize for not answering that yet. In general, I prefer to write a post on each drug and go deep enough so that we understand how it works and how it is applied in the best way. However, if you like to start such a post, I will be glad to review it and if it adds value I will publish that as a post. If on the other hand, you do not have time for that but you have some nice findings on various re purposed drugs, you can always create topics in the Forum with less content. Please let me know which approach you prefer.

              Kind regards,

            2. Hi D,
              Yeah i agree, i Will post in the forum and if you like it and wish you can repost. Cheers w

      1. Emad, yes it is so frustrating!

        Whenever you see these off label results you typically never hear about them again.
        There probably are few pharmas that would be willing to spend money on something that is
        beyond patents.

        You just need to be aware that some of these do not have a marketing department behind them, yet might be of some help.

  29. I just wanted to express a personal theory that may very well be wrong. SO PLEASE take this with a big chunk of salt.
    “tumor markers are not to be used as an indicator of tumor size but only as an indicator of it outputting antigen in higher or lower quantity, mostly due to slower or faster metabolism”.

    1. Alex how is your mom and how are you?
      I miss talking with you on skype.
      I am lost for some weeks i know.
      But i had to do it for myself, a period without searching and far from thinking cancer.
      I hope she responded well to chemo.
      And i hope you understand me.

      1. I understand you brother.
        It is very hard for my mother and i as well. Life can sometimes seem like a living nightmare sadly. And even more sad is that so many of us go trough this. You know well i can keep on adding.
        Soon another chemo cycle, maybe avastin next to it.
        To be honest i don’t even know if it’s worth doing the markers or other independent testing, in the end my mom has to feel better, we are in a condition where independent tests won’t do much, she has to get better a bit or more, so far only bad things have happened since her “neuropathy” and i let’s say had a wake-up call that told me to kinda leave things to the “professionals”, i will help as much as i can on the side but the hard truth is that i can’t help with real treatment like an oncologist can.
        Still with the incredible help received from Daniel and you, the great advice and people here…… it’s hard to describe the joy and sorrow.
        I still hope you and everyone else will experience positive things and maybe even healing. We’re still in the fight, but it got to an almost impossible situation.
        I look forward to talking to you again

        Our best wishes,
        Alex & Mother!

  30. Small update

    my parents traveled today to Germany for the next TACE

    thankfully my father did manage to get the visa for 2 more years for both him and my mother

    also managed to get some help from the government to continue doing more TACE sessions

    in Friday July 21 at early morning , they will do the second TACE , and they will see the results after 2 months from the first one

    I’m a little bit worried , but I hope its fine

    I will share the results as soon as it comes

  31. New Update :

    according to what I did hear from my parents until now that there is 10% improvement since the last time (May-22)

    my mother did finish the second TACE

    my father will talk with prof Vogl in details

    1. 10% is much better than nothing. Another good thing about it is that the chemo should arrest the growth of the tumours for a period.

      After I finished my liver embolization of four tumours from April to August, the November scan showed no new growths. So three months at least I was good. Unfortunately, in March the CT showed six new tumours in the liver, all under 1cm.

      If nothing else, it buys you more time to look for more treatments, and that’s always valuable.

      1. yes its more about buying time to find better solutions

        and indeed its a very valuable time to buy, if things did continue to get worse like before TACE , perhaps my mother wouldn’t made it to now

        but with this now we have much more months , we can focus more on what to do next


        btw , how things going with you after you stop Sef-chemo ? hope you are managing things like you always doing

        all the best

        1. Time is always valuable 🙂 keep the hope.

          In general I have been worse since SEF chemo. My hemoglobin hasn’t recovered and it’s been two months. I already have orthostatic tachycardia due to nerve severing during surgery, and having low hemoglobin makes it hard to stand for more than a few seconds or to climb stairs. I have to see about an EPO injection or a transfusion. I developed a slight edema in my left leg, which I assume is from a tumour compressing a vein, but that also makes it a bit harder to walk. I got sick and have been coughing for 3 weeks now so hoping that has nothing to do with the cancer, and I have little aches and pains.

          But honestly, I’m in good spirits. I haven’t been hindered from going and seeing friends or being independent, it’s just a mild hinderance and I started the T4 strategy two weeks ago so I’m hoping that’ll shrink things a bit. Thanks for asking!

            1. Thanks Daniel.

              Actually tonight I got a CT scan report of my abdomen and pelvis. I did the scan on Tuesday. The results arent very good. All results compared to March. Developed a multitude of hepatic metastases on virtually all segments of the liver – the largest being 5.4cm. 8cm lymph tumour markedly compressing my left renal artery, which grew from 6.5cm. Potential thrombosis into an iliac vein from a large iliac tumour. 4cm or so mesenteric lymph metastasis grown from 1.5cm or so. And various smaller mesenteric tumours. Fractured ischial tuberosity from a tumour but thankfully no other bone metastases.

            2. Thanks Daniel. I’m hoping that since my type arises from endocrine cells that the T4 hormone therapy can work something out. Like I said, I still feel fairly good so hopefully there’s still some time to work with.

            3. I’m very sorry to hear this Meech

              why not to consider other clinic that can do systemic therapy ? like Dayspringcancerclinic or something similar

              you may not be experienced on using IVs to treat yourself , but other oral options that maybe interesting to me is T4 strategy and also Methylglyoxal or Thalidomide

              I strongly believe that you can overcome this and bring the tumors down like you always did before , I will pray for you to live a happy long life

            4. Thank you Emad. I am trying the T4 thing so hopefully that’ll work. I’m also considering Dr. Jason Williams in the US, but I have to see if I qualify.

              Praying for the best for you as well.

            5. I’m happy to hear that you already have a good plan , I hope T4 depletion will do the job

              and of course Dr Jason should be one of the best choices for the next


            6. Hi Meech,

              Great to see your attitude. How about Mebendazole and Thalidomide? Did you try these?


            7. Thanks for the suggestions, W. I wouldn’t mind trying thalidomide under one of Dr. Hada’s protocols.

              Mebendazole, although I’m sure has an effect, I’m not 100% sold on as being right for me. I’m in a private FB group where most members are taking a protocol which include some mebendazole. I asked if anyone has seen any shrinkage or if everyone has basically just helped to slow their growth or stabilize things and nobody came forward saying they had shrinkage. But for most, stabilization and slowed growth rate are definitely important. For me though, I do need to shrink thing’s as the status quo isn’t great.

    1. Hi Jcancom

      thank you always for your feelings , I should be happy that you are always here with us , and especially helping me a lot

      unfortunately can’t be happy for now , I’m worried about my brothers Alex and Ergin , no way to feel happy until their mothers feel better , also the same for Pouya I wish he feels better one day soon

      this is the world with cancer , we should do our best before time is up


      regarding the results after TACE , I did administrate 15 3-BP IV and 7 Salinomycin IV for the past 2 months , it seems like either TACE is not working well or (3-BP + Sal) is not , or maybe both have minimal effect , not very sure

      I can’t know which one is really working , and I can’t be sure until we stop one of them

      1. Dear Emad,
        May be it is not a miracle but it gives you lots of months to try other treatments.
        Stable is also a good thing for us.Thats not we want ofcourse but we must think like that.
        For me,you did a great job.And you will.

        1. Thank you always Ergin

          I wish if I can help you just like how greatly you are helping me

          we did face a hard times , but will not stop doing new things and new strategies until we both save our mothers

      2. Hi Emad,

        I am happy to hear you are seeing positive results. Yes you will not know what works and what not. Or maybe the combo is that helps. Regardless, as long as there are positive results (stable dis. or remission) I would not change anything.
        I remember the tumor was relatively large so I can imagine it will take some time to clean up the location.

        With 3BP I would take a short brake from time to time in order to let the responding cells develop back so that the tumor can maintain response to 3BP.

        Kind regards,

        1. Of course I will not change my strategy as long as its working

          yes the tumors are big , if they are small as in the past I think we will probably have about 50% improvement

          thank you for the advise , and thank you for everything you did for me

          best wishes

  32. Dear All, I would like to share good news. Marker CA125 drop to normal after 2 cycles of Taurolodine. We got our aim: to start the vaccine cocktail under normal condition. I will update with or experience in Germany.

    Best wishes
    Dr A Hernandez

  33. Hi Emad
    I have already wrotten before but in summary, my sugestions are:
    Do a sensitivity test, so you can use the most active substances against the tumor.
    iv is the better route. Do the therapy in cycles.
    be aggressive but always always use the right substance. Not which is good for one person is good for another one.
    In our case, we did the sensitivity test, and try to give iv the substances more active. We did a molecular study with the NEw generation system, and we developed an specific vaccine for our specific mutations. Then leave your body to kill the rest of the cells. Avoid chemo and radiotherapy when possible, the vaccine is not effective during this therapies because your immune system is to weak.

    1. thank you so much Alberto

      one more question , did you test for Taurolodine before to see if its effective ?

      also is it possible to share the source that you did use ?

      always wish to hear good news from you

      Kind regards

      1. HI Emad, yes we tested before the sensitivity, there r different companies as Maintrac, Bojar, in Germany and also in Greece there is a famous one. Pick it up one and do it, do not work blind.
        Best wishes

  34. Hi dear friends in this website, I miss you all

    sorry for not being around too much these days , the internet connection and electricity is almost off most of the time these days in Libya

    Last update : the results after second TACE are better than the first one

    and what we did is : TACE + Sal + 3-BP, no systemic chemo

    the past 2 cycles are done in the right side of the liver , but this time prof Vogl decided to treat the left side of the liver

    i don’t know if its normal but this time it was very painful , my mother have severe pain these days , and sometimes make her faint

    prof Vogl said that its temporarly , and prescribed some medications to lower the pain , i noticed the pain is slowly decreasing , but still she feels a bad pain in the target position and also in her back

    regarding the treatment plan , i don’t understand why prof Vogl believes that we are doing good and don’t need more than 1 or 2 other TACE sessions

    but in anyway , we did reach the limit of receiving help from government , its hard to continue do more than that

    so the next big fight will be after we finish TACE , trying to manage the disease with hormonal therapy + others like Sal + 3-BP …

    that’s all I have now, wish you all the best

  35. Hi Alberto,
    What kind of treatment are you having in Germany. Is it a vaccine made from blood? Also, I would be most interested to hear about your wife’s experience, both with taurolidine and with the vaccine and treatment in Germany. This is something I considering too and would love to hear how it went. Thanks..

    1. Hi Hectoria, if you want Alberto to receive a notification with your questions you need to add a comment as a reply to his comment. (Now you created a new comment and he may not be aware of your question.)

      1. Please Alberto,
        Do not play with our senses.Do not try to be popular.Look how Emad tries to save moms life.It is not a game.He began MG,not a joke.
        Be a man like a MAN like Daniel.
        Be brave.
        Make me to apologise from you in this website
        Do not talk like a puzzle please.

          1. Dear Alberto, I apologize for this. We all are going through difficult times and sometimes we may say things we did not meant to. Knowing Ergin, I think this was the case. I hope you will keep updating us here on the approaches and the results you are seeing as they are very valuable for many people reading this website. Kind regards, Daniel

          2. Off Dear Alberto,
            I mixed Your name with Halabe.
            I am very sorry about this.I respect you and your work too much ofcourse.
            When i see his name on Emad ‘s page i totally became a different person.

        1. Hi Ergin,

          We all here are fighting on the same side. Each of us have own way of fighting and communicating. Alberto is a very nice and wise man, as you and many here, fighting for his dear wife. He may not have time always to respond fully to our questions, but his short post here are very valuable. You have to realize that many are reading this website, some are seeing very good results with some of the treatments but not writing here. In the best case sometimes they write to me in private. So, we should highly appreciate that Alberto takes time to update us here regarding the outcomes of the treatments he is using for his dear wife.
          I hope you realize that, as I very much appreciate you. Thank you in advance for reconsidering your view.

          Kind regards,

  36. A little update : I stopped Salinomycin and 3-BP temporarily , and now I’m giving my mother Methylglyoxal orally about 23mg/kg

    I want to see if there is any difference in results , and will turn back to Sal + 3-BP after the forth TACE session

      1. no , we didn’t do any marker test for months

        maybe after the next session we will do one , we will do it if its the last TACE session

        no need for it now while we are doing MRI

    1. Hi Emad,
      How are you and mom?I hope you saw some good responces with MG.
      Did you observe any side effect?
      Our chemo sensitivity test came.I lost my faith on that test.Please do not think you are loosing stg if you dont do that test.
      I will send you by mail.If anyone interested ,i can send it.
      Best wishes

      1. Hi Ergin

        My mother is fine these days , we still didn’t notice any side effects from MG

        also like when using 3-BP and Sal , we don’t know if the response is due to them or due to TACE or due to the both

        we didn’t do any tumor marker test for months , we are just following up with MRI before every TACE cycle

        but why you lost faith on the test ? I thought its good to have one for my mother too

        I hope the results are reliable

      2. i’m interested brother,
        send me.
        my mother is now in hospital for chemo and other paralisys problems
        Tarceva seems to be doing something good next to the side effects but nothing very dramatic so far.
        Little to no cancer pain and some nervous recovery on her chest.
        take care bro
        Tell me if i can help.

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