A fit for ketogenic diet

One short but important point: for cancers with no or limited mitochondria use ketogenic diet. That will be very effective. Why? The cancer cells will not be able to switch on fuels other than glucose. ccRCC seems to be a cancer characterized by low to no mitochondria.

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5 thoughts on “A fit for ketogenic diet

  1. Daniel,
    We should talk. I am currently using the ketogenic diet combined with immunotherapy (Bravo Yogurt) which seems to be working.

    Makes a lot of sense. Keep carbs as low as possible, moderate protein, high fat. The ketogenic diet macro-nutrient targets are built into cronometer.com by Dr. Mercola. I started this diet in Sept and it looks like it is working (I take videos of my tumor to see changes over time). Can’t be sure if it’s the ketogenic diet or the yogurt or the combination. I think the diet weakens the cancer by keeping glucose to fasting levels while the yogurt is the perfect treatment for HNSCC. A hallmark of HNSCC is its ability to deactivate your immune system in particular the macrophages. Cancer turns off a precursor enzyme needed to activate the macrophages. The yogurt provides GcMAF which doesn’t need the enzyme to activate the macrophages.

    There is tons of research about how probiotics modulate the immune system. Keeping carbs low and reactivating your immune system my work on many cancers.

    John

    1. Hi Gokhan,

      Thanks a lot for your comment on my very short post from 2015!

      It’s great to see that Maxime Benoit, MD from Angers, France worked out exactly this idea and published results in 2018, indicating that the idea was actually good 🙂

      I am not the biggest supporter of ketogenic diet but it just make’s sense for ccRCC.

      Indeed, cancer uses glutamine as a fuel too, but that is less possible in ccRCC as this type of cancer cells have no or limited mitochondria, which is required for Glutamine to be converted in energy.

      The positive study you shared here is perfectly addressing the idea I shared in the post above (KD in ccRCC), while the negative study is not addressing this idea since is related to KD in RCC.

      Thanks again.

      Kind regards,
      Daniel

  2. Hi Daniel,

    thank you for all you do for us.

    Do you know this? https://guerir-du-cancer.fr/wp-content/uploads/2020/02/Maurice-Isra%C3%ABl-2.pdf
    “Maurice Israël (2020) The metabolic rewiring observed in cancer renders tumor cells
    dependent of ketone bodies and vulnerable to SCOT inhibition”.
    It’s a paper from university of Paris and the team of Dr. Schwartz (Metabloc)

    If it’s correct it would mean that ketogenic diet is not a good idea.

    And if it would be correct the inhibition of SCOT (Succinyl-CoA: 3-oxoacid-CoA transferase) is a genius idea and the premium key to kill cancer on metabolic pathway.

    Best regards
    Wolfgang (from Germany)

    1. Hi Wolfgang,

      Thank you for the kind words and for the paper. I do know Dr. Schwartz and his website, but I haven’t seen yet this last paper. I just went through it now and it looks indeed interesting. I will need to look into the details of SCOT and see if there is any way around that for the cancer cells, but if there is no way around it, inhibiting SCOT could be a great idea.

      I do appreciate the scientists working on ketogenic diet but I am not the best friend of ketogenic diet concept – from that point of view, this paper resonates with me. But I will need to better understand the mechanisms around SCOT.

      Thanks a lot again!

      Kind regards,
      Daniel

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