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Topics: 36 / Replies: 589
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RE: Another Metabolic one:Aldehydes

johan, thank you for calling me back to the forum! I greatly enjoy posting here and hopefully my posts are helpful for those in need when nothing else...

10 months ago
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RE: Another Metabolic one:Aldehydes

D, I had not been sure about the microbe theory of cancer, though as noted above evidence suggests it has a role in prostate cancer. It is difficult t...

11 months ago
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RE: Another Metabolic one:Aldehydes

A connection of microbes to prostate has been reported. This could have substantial clinical impact as this would seem to have a reasonably straight f...

11 months ago
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RE: Another Metabolic one:Aldehydes

johan, thank you for the link! I have read up further on ethyl pyruvate, it continues to look like a good one. We have a pretty good idea of what so...

1 year ago
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RE: IVC and (or?) Ferroptosis when Immunotherapy only

@Abiding, I have just posted about ethyl pyruvate to the Another Metabolic One thread. This looks quite good. It pressures cancer metabolism and the F...

1 year ago
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RE: Another Metabolic one:Aldehydes

Very exciting! Very very exciting! From time to time on forum we gain some insight that moves us forward; the above figure might just be one of thos...

1 year ago
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RE: Another Metabolic one:Aldehydes

I posted this idea to this thread about a year ago. This was originally posted to the cancer compass thread as it seemed intriguing to me at the time....

1 year ago
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RE: Another Metabolic one:Aldehydes

johan, I see from your other post that you have figured out how to upload figures. I think that you are using the "Browse" file approach. Another way ...

1 year ago
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RE: Another Metabolic one:Aldehydes

@johan, thank you. There is so much cancer research; it feels like it is almost infinite.The BBB is one of the many challenges present when thinking i...

1 year ago
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RE: Another Metabolic one:Aldehydes

Anyone have any ideas on how to get a small molecule into the brain? Intranasal? Carrier protein/molecule to move substance past the BBB? What prop...

1 year ago
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50 mM!

@johan, Why didn't they go higher dose with the Vitamin C? One of the articles seemed to hint that this would make sense as one of the mechanisms of a...

1 year ago
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RE: IVC and (or?) Ferroptosis when Immunotherapy only

Abiding, sorry I have not been active on forum for a while; I have been diving into the oceans of cancer research -- it truly feels almost infinite. T...

1 year ago
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RE: IVC and (or?) Ferroptosis when Immunotherapy only

Abiding, this looks very encouraging. You mentioned the G12D mutation, apparently this can enhance 3-BP response when treated with Prima-1 (Prima1 is ...

1 year ago
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RE: IVC and (or?) Ferroptosis when Immunotherapy only

@Abiding, I realize how overwhelming all of this can be, though it might be a good idea to start loading up the buggy. There are a large number of met...

1 year ago
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RE: Contemporary Perspectives on the Warburg Effect Inhibition in Cancer Therapy

johan, thank you for posting this article. I am sure that you knew that I would be interested! I think that with 3-BP about ready to enter the clinic ...

1 year ago
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RE: IVC and (or?) Ferroptosis when Immunotherapy only

Abiding, I am so glad that we have johan on board to help you! He has a lot of insight into cancer and has great advice. There is so much to learn and...

1 year ago
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RE: IVC and (or?) Ferroptosis when Immunotherapy only

The chemothermia clinic's results with lung cancer have been quite impressive. They use the metabolically supported chemo approach along with ketogeni...

1 year ago
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RE: IVC and (or?) Ferroptosis when Immunotherapy only

I am sorry Abiding, I will not be much help on the question of TLS. However, as I noted, for the patients treated with vitamin c who developed necro...

1 year ago
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RE: IVC and (or?) Ferroptosis when Immunotherapy only

What you really should be trying for is a nice gradual long term in tumor markers. As the tumor mass decreases so too does the risk of TLS. I have ...

1 year ago
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RE: IVC and (or?) Ferroptosis when Immunotherapy only

Abiding, I usually defer to D's best judgment on the skill testing questions. However, you need to realize that in most instances tumor collapse wil...

1 year ago
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RE: IVC and (or?) Ferroptosis when Immunotherapy only

Regarding the metabolic collapse idea: I would not try to overthink it. Most cancers are not fragile. Those cancers (that are like clear cell renal ca...

1 year ago
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RE: IVC and (or?) Ferroptosis when Immunotherapy only

Metabolic approaches with lung cancer have been especially favorable.

1 year ago
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RE: IVC and (or?) Ferroptosis when Immunotherapy only

Abiding, there are no easy answers for many of the problems that we have faced trying to help people. Typically, tumor collapse is not a big problem i...

1 year ago
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RE: IVC and (or?) Ferroptosis when Immunotherapy only

Necrosis and fatality is not the objective -- it a problem- though what it dramatically demonstrates is that a metabolic approach can be highly powerf...

1 year ago
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RE: IVC and (or?) Ferroptosis when Immunotherapy only

Abiding, I know that there are so many questions and it does take so long to try and understand things. That is where those on forum can help you; you...

1 year ago
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RE: Metformin + Keto diet = 3-Bromopyruvate (3BP) ?

mahdi2, Dayspring is probably the world's top 3-BP clinic. The protocol that they use includes 3-BP, ketogenic diet and vitamin C among others. This i...

1 year ago
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RE: IVC and (or?) Ferroptosis when Immunotherapy only

AbidingToday, I understand how overwhelming trying to digest all of this information all at once on cancer can be. Here is my quick recap from my jo...

1 year ago
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RE: Another Metabolic one:Aldehydes

@johan, this is a very insightful idea that you have posted. The mind shapes our awareness in powerful ways; we align our perceptions to fit our belie...

1 year ago
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