@daniel could you check on the antispam setting of the forum, I just typed a response to @ram including a link to Pubmed and it didn't get thru. annoy...
meant to type "anticancer synergies"
@ram just recently I started looking into pancreatic cancer, from my specific perspective of anti-synergies I must add, but I'll expand my searches an...
@ram thanks! In a pro-oxidant strategy, you're pushing cancer cells beyond their capacity to deal with oxidative stress. In my view, chemotherapy alre...
@ram and since you are planning on using apigenin and luteolin note that there are possible synergistic effects among these molecules, for more info o...
@ram studies have used varying doses, anticancer effects appear to start at relatively low doses albeit not likely achievable through diet. But yes sa...
@ram half-life is short about 5 hours I believe so it's best to spread it out over the day e.g. morning, noon, evening
@ram 2 to 3 days generally is enough time, yes.
@ram you need to check the supplements against each drug used in the cancer treatment. Some supplements can interfere with how much of the drug enters...
@ram Maybe a little there's no way to tell but natural products can reduce harm to normal cells e.g. curcumin reduces cytotoxicity of 5-FU ref Prote...
@ram I wouldn't worry about any antioxidant activity you might find in the scientific literature about PL, if any it's weak and will not produce any p...
and btw, aspirin isn't a good combo with metformin
GRP78 is overexpressed in TNBC Aspirin potentiates celecoxib-induced growth inhibition and apoptosis in human non-small cell lung cancer by targetin...
Protective effect of lycopene on celecoxib-induced hepatotoxicity
@chris48 be aware that taking metformin (part of COC protocol) with Celecoxib may increase the risk of a rare but serious and potentially life-threate...
@chris48 or calcifediol which is the precursor of calcitriol. Also, note that magnesium is crucial in order to activate Vit D.
@chris48 Hi Chris, good to hear from you! Recurrence-free survival doesn't always improve overall survival. Here's an interesting review: Opioid ...
Study finds hallmarks of T cell exhaustion within hours of tumor exposure
A T-cell killing a cancerous cell:
Noteworthy, TOP2A acts as a co-activator of beta-catenin. Ellagic acid, hydroxyquinone (bearberry leaf extract) inhibits TOP2A.
I don't think I've posted this before: β-Catenin Is Required for the Tumorigenic Behavior of Triple-Negative Breast Cancer Cells (can't post a lin...
Nifuroxazide attenuates experimentally-induced hepatic encephalopathy and the associated hyperammonemia and cJNK/caspase-8/TRAIL activation in rats
Nifuroxazide boosts the anticancer efficacy of palbociclib-induced senescence by dual inhibition of STAT3 and CDK2 in triple-negative breast cancer ...
@rosed great! Good question, and in fact I haven't come across much about mustard seeds, not anything I can remember other than what you mention regar...
Nigella sativa seed reduced galectin-3 level and liver fibrosis in thioacetamide-induced liver injury in rats
Effects of Aspirin and Indomethacin on Galectin-3
I've attached an updated pathways diagram TNBC-THEORY-17.jpeg
@rosed indeed, it has become excessively influenced by politics.
Naloxone Counteracts the Promoting Tumor Growth Effects Induced by Morphine in an Animal Model of Triple-negative Breast Cancer
Hibiscus flower extract selectively induces apoptosis in breast cancer cells and positively interacts with common chemotherapeutics " Conclusion ...