The recent news are related to combinations of Opdivo (nivolumab) and Keytruda (pembrolilzumab) tested in clinical trials for patients with refractory multiple myeloma. Here is discussed the specific trials that have been halted for:
These drugs are some of the stars-drugs developed by some of the major pharmaceutical companies as part of the immunotheraphy wave of drugs to treat cancer. I already discussed shortly some of these drugs, here (Ref.).
The clinical trials have been halted due to large number of deaths that have occurred during the clinical trials.
This is important information given that private clinics around the world are using the anti PD1 drugs Opdivo and Keytruda as off-label drugs, possibly also in multiple myeloma patients.
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