Surgery or radiotherapy or chemotherapy causes stress which in turn stimulate production of tumor-derived extracellular vesicles (TEVs).

Resperine is a drug that is used for the treatment of high blood pressure  https://en.wikipedia.org/wiki/Reserpine

Resperine also prevents tumor-derived extracellular vesicles (TEVs) from fusing to healthy cells and sharing their cargo of disease-promoting molecules.

https://www.sciencedaily.com/releases/2019/01/190115111922.htm
https://www.cell.com/cancer-cell/fulltext/S1535-6108(18)30555-5