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15/02/2020 11:52 pm
" PTEN is an important tumour suppressor – a gene that appears to stop healthy cells from becoming cancerous – and it is switched off in around one in eight patients with melanoma and in almost half of those who carry a mutation in another cancer gene called BRAF. Scientists think one way melanoma cells can metastasise is by losing their PTEN function, increasing their shape-shifting ability and in turn enabling them to move to many different tissues within the body."