Fenbendazole vs. Mebendazole
I have ovarian cancer and had three chemotherapy treatments with Avastin and Neulasta then the debulking surgery and another 3 chemo treatments with Avastin and Neulasta. I have no BRCA 1 or 2 mutations (hereditary or tumor). Based on the Foundation Medicine Report, I am HRD negative, TP53 R248W mutation, LYN, PlM1 and TERC amplifications. I have been on Joe Tippen’s protocol since late February 2020. My question concerns Fenbendazole (FZ). Do you if FZ will kill the ovarian cancer cell root? Or, should I take mebendazole or a combination of both? If mebendazole, how much to take daily? Do you know if FZ will suppress the TP53 mutation? I heard that mebendazole is more effective on TP53 mutation. I also read that the difference between Fenben and Meben is 1 atom for patent purposes. The part that is effective against cancer is effective in both. This information is from a PhD chemist.
My oncologist said there are no therapies or clinical trials for my setting. The oncologist is recommending continuation of Avastin every three weeks and niraparib (Zejula) daily. I am aware of the serious side effects with Zejula.
Your opinion is greatly appreciated.
I would combine both mebendazole and fenbendazole, they are well tolerable possibly due to their low bioavailability. I would not be afraid to increase the doses and combine them with cimetidine which will help increase the bioavailability of both.
@manuone I have a few questions regarding bioavailability. For example, if you combine cimetidine with fenbendazole, does the bioavailability of the fenbendazole decrease if you also take other supplements at the same time?
I’m just starting to use Fenbendazole for metastatic prostate cancer. Any suggestions as to the protocol and dosage I should use?
Hi, Daniel wrote a comprehensive post on this protocol:
Can Fenbendazole and Mebendazole be taken together at the same time?
I think this may be a good idea. The only challenge may be when both are taken at high daily dose, as that may come with side effects. When taking about 200mg of each daily, I would not expect important side effects. However, even in this case, I would not start with taking them both, but I would first introduce one and after several days I would introduce the other one and observe if there is any adverse reaction.
- Hi, I believe I have colon and stomach cancer. I would like to start a protocol of fenbendazole, but I'm not sure if it interacts with the one medication I'm on. Its called Clonidine Hcl. I cant find info anywhere and I really need to start?