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Fenbendazole vs. Mebendazole


Corkeyjo
(@corkeyjo)
Joined: 1 year ago
Posts: 1
Topic starter  

Daniel,

I have ovarian cancer and had three chemotherapy treatments with Avastin and Neulasta then the debulking surgery and another 3 chemo treatments with Avastin and Neulasta.  I have no BRCA 1 or 2 mutations (hereditary or tumor).  Based on the Foundation Medicine Report, I am HRD negative, TP53 R248W mutation, LYN, PlM1 and TERC amplifications.  I have been on Joe Tippen’s protocol since late February 2020.  My question concerns Fenbendazole (FZ).  Do you if FZ will kill the ovarian cancer cell root?  Or, should I take mebendazole or a combination of both?  If mebendazole, how much to take daily?  Do you know if FZ will suppress the TP53 mutation?  I heard that mebendazole is more effective on TP53 mutation.  I also read that the difference between Fenben and Meben is 1 atom for patent purposes. The part that is effective against cancer is effective in both.  This information is from a PhD chemist.

My oncologist said there are no therapies or clinical trials for my setting.  The oncologist is recommending continuation of Avastin every three weeks and niraparib (Zejula) daily.  I am aware of the serious side effects with Zejula.

Your opinion is greatly appreciated.

Corkeyjo


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Manuone
(@manuone)
Joined: 4 years ago
Posts: 148
 

I would combine both mebendazole and fenbendazole, they are well tolerable possibly due to their low bioavailability. I would not be afraid to increase the doses and combine them with cimetidine which will help increase the bioavailability of both.

Kind regards


Daniel liked
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rich.smoz
(@rich-smoz)
Joined: 4 months ago
Posts: 2
 

@manuone I have a few questions regarding bioavailability. For example, if you combine cimetidine with fenbendazole, does the bioavailability of the fenbendazole decrease if you also take other supplements at the same time?


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Jwaynel73
(@jwaynel73)
Joined: 3 months ago
Posts: 1
 

I’m just starting to use Fenbendazole for metastatic prostate cancer. Any suggestions as to the protocol and dosage I should use?


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johan
(@j)
Joined: 3 years ago
Posts: 590
 

@jwaynel73 

 

Hi, Daniel wrote a comprehensive post on this protocol:

https://www.cancertreatmentsresearch.com/fenbendazole/

Best,


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okeyokeh
(@okeyokeh)
Joined: 2 months ago
Posts: 1
 

Can Fenbendazole and Mebendazole be taken together at the same time?


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Daniel
(@daniel)
Admin
Joined: 6 years ago
Posts: 1046
 

Hi @okeyokeh,

I think this may be a good idea. The only challenge may be when both are taken at high daily dose, as that may come with side effects. When taking about 200mg of each daily, I would not expect important side effects. However, even in this case, I would not start with taking them both, but I would first introduce one and after several days I would introduce the other one and observe if there is any adverse reaction.

Kind regards,
Daniel


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Maphteach3
(@maphteach3)
Joined: 5 days ago
Posts: 1
 
  • Hi, I believe I have colon and stomach cancer. I would like to start a protocol of fenbendazole, but I'm not sure if it interacts with the one medication I'm on. Its called Clonidine Hcl. I cant find info anywhere and I really need to start?

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