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Daniel RE: Cryptotanshinone Inhibits Ovarian Tumor Growth and Metastasis by Degrading c-Myc and Attenuating the FAK Pathway  

By Daniel, 6 days ago

  Nice. Already working on it at MCS Formulas. Kind regards,Daniel
johan Cryptotanshinone Inhibits Ovarian Tumor Growth and Metastasis by Degrading c-Myc and Attenuating the FAK Pathway  

By johan, 6 days ago

  "Cryptotanshinone (CT), a natural compound derived from Salvia miltiorrhiza Bunge (Danshen, a traditional Chinese medicine), has been shown antitumor activity in various cancers. However, it remains u...
johan Pomegranate juice anthocyanidins induce cell death in human cancer cells by mobilizing intracellular copper ions and producing reactive oxygen species  

By johan, 6 days ago

  "Anthocyanidins are the most abundant polyphenols in pomegranate juice. This class of molecules includes Delphinidin (Del), Cyanidin (Cya), and Pelargonidin (Pel). Using prostate, breast and pancreati...
johan The synergistic effect of eucalyptus oil and retinoic acid on human esophagus cancer cell line SK-GT-4  

By johan, 6 days ago

  Conclusion Our research discovered that the two chemicals worked together to create a synergistic effect. This synergistic effect could be attributed to a close connection between external and interna...
johan RE: TNBC / testing strategies in a NED situation  

By johan, 1 week ago

  Berberine Reverses Breast Cancer Multidrug Resistance Based on Fluorescence Pharmacokinetics In Vitro and In Vivo "In this work, Ber was demonstrated as an ideal MDR reversing agent. The MDR reversal ...
johan RE: TNBC / testing strategies in a NED situation  

By johan, 1 week ago

  Posted by: @chris48 I think we will definitely take Aspirin, but we are unsure about the dosage. I am aware of people using several grams a day (slowly up titrate starting with one regular aspirin),...
johan RE: TNBC / testing strategies in a NED situation  

By johan, 1 week ago

  "Luteolin inhibits the metastasis of triple-negative breast cancer" "Sulforaphane inhibits HER2+ and triple-negative breast cancer" "Quercetin and fisetin inhibit TN cell migration"
johan RE: TNBC / testing strategies in a NED situation  

By johan, 1 week ago

  Foods to eat & avoid for triple-negative (ER-/PR-/HER2-) breast cancer:
johan RE: TNBC / testing strategies in a NED situation  

By johan, 1 week ago

  @chris48 here's a website with good information on breast cancer:
Shanti RE: Clioquinol Zinc Ionophore for Terminating Advanced “Decreased Zinc” Testosterone-Dependent Prostate Cancer: A Case Report  

By Shanti, 1 week ago

  Wow, I didn't realize clioquinol had so much iodine! His symptoms were not of the thyrotoxicosis variety, more so fatigue and, oddly, he would often come down with a cold at the end of a run of clioqu...
Chris48 RE: TNBC / testing strategies in a NED situation  

By Chris48, 1 week ago

  @daniel @j Thank you so much for your input! Very interesting information that we will look into more deeply during the next days. I think we will definitely take Aspirin, but we are unsure about the ...
Shanti RE: Prostate-Specific Antigen is Angiogenesis/Tumorigenic or Anti-angiogenic/Anti-metastatic?  

By Shanti, 1 week ago

Forum Just Science
  Interesting research, I didn't realize PSA could have an antiangiogenic effect. I had seen it previously postulated that it may promote metastasis due to its proteolytic activity, but it was just theo...
Chris48 RE: TNBC / testing strategies in a NED situation  

By Chris48, 1 week ago

  Posted by: @laika Hi @chris48 Was her tumor PD-L1 positive, and is there any possibility of getting her on adjuvant Keytruda? It is now FDA-approved for high risk early stage TNBC in the USA. Even a ...
medline Prostate-Specific Antigen is Angiogenesis/Tumorigenic or Anti-angiogenic/Anti-metastatic?  

By medline, 1 week ago

Forum Just Science
  Anti-angiogenic properties of prostate‐specific antigen Abstract The prostate produces high levels of prostate‐specific antigen (PSA, also known as kallikrein‐related peptidase 3, KLK3), which...
medline Anticancer Effects Of Anesthetic Drugs  

By medline, 1 week ago

Forum Surgery
  Drug Repurposing: The Mechanisms and Signaling Pathways of Anti-Cancer Effects of Anesthetics Abstract Cancer is one of the leading causes of death worldwide. There are only limited treatment strategi...
medline RE: Clioquinol Zinc Ionophore for Terminating Advanced “Decreased Zinc” Testosterone-Dependent Prostate Cancer: A Case Report  

By medline, 1 week ago

  Jan 07, 2021: PSA=1.00 PRL=16.0 Casodex Mar 09, 2021: PSA=0.68 PRL=3.00 Casodex + Cabergoline Jun 02, 2021: PSA=0.73 PRL=2.00 Casodex + Cabergoline Aug 02, 2021: PSA=0....
johan RE: Clioquinol Zinc Ionophore for Terminating Advanced “Decreased Zinc” Testosterone-Dependent Prostate Cancer: A Case Report  

By johan, 1 week ago

  Posted by: @shanti Hi @johan! Thanks for checking in :-). When my husband has taken breaks from androgen deprivation, clioquinol and high-dose zinc was the only therapy we tried that seemed to have ...
johan Role for Dopamine in Deadly Brain Cancer  

By johan, 1 week ago

Forum Brain cancer
  "A Northwestern Medicine study has demonstrated how the deadly brain cancer glioblastoma exploits dopamine in order to evade treatment and fuel growth, and suggests that targeting the neurotransmitter...
Shanti RE: Clioquinol Zinc Ionophore for Terminating Advanced “Decreased Zinc” Testosterone-Dependent Prostate Cancer: A Case Report  

By Shanti, 1 week ago

  Hi @johan! Thanks for checking in :-). When my husband has taken breaks from androgen deprivation, clioquinol and high-dose zinc was the only therapy we tried that seemed to have any impact on the PS...
Daniel RE: TNBC / testing strategies in a NED situation  

By Daniel, 1 week ago

  @chris48 Dear Chris, I am sorry to hear that there is some progression. Time to surgery is relatively short but here is a study indicating it makes very much sense to use HydroxyChloroquine prior to s...
johan RE: help with dosis and interactions supplements with chemo and immuno.  

By johan, 1 week ago

  Hi @joanp, I don't think the supplements you mention could negatively impact the effectiveness of chemo. N-acetylcysteine and glutathione are best avoided during active chemotherapy. My own preference...
johan RE: TNBC / testing strategies in a NED situation  

By johan, 1 week ago

  @chris48 I am very sorry to hear of this recurrence. @daniel might have some good suggestions to consider prior to surgery. The suggestions I have posted above remain relevant post-surgery. In additi...
johan RE: Clioquinol Zinc Ionophore for Terminating Advanced “Decreased Zinc” Testosterone-Dependent Prostate Cancer: A Case Report  

By johan, 1 week ago

  sorry, @shanti
johan RE: Clioquinol Zinc Ionophore for Terminating Advanced “Decreased Zinc” Testosterone-Dependent Prostate Cancer: A Case Report  

By johan, 1 week ago

  wow, impressive. @chanti you have been using this treatment for your husband, how is he doing?
Chris48 RE: TNBC / testing strategies in a NED situation  

By Chris48, 1 week ago

  Hi everybody, unfortunately we are not in a NED situation anymore. This week, a new tumor (same physiology than primary tumor) was detected via ultrasound (it was not visible on mammography or CT scan...
JoanP help with dosis and interactions supplements with chemo and immuno.  

By JoanP, 1 week ago

  Hello everyone, I would like to have advice on how the following supplements would work that I already have, but we have waited to apply them to know the exact treatment of my father's cancer, especia...
Daniel RE: Clioquinol Zinc Ionophore for Terminating Advanced “Decreased Zinc” Testosterone-Dependent Prostate Cancer: A Case Report  

By Daniel, 1 week ago

  Super! Thanks a lot! This deserves to be sent to the subscribers of this website. Kind regards, Daniel
medline Clioquinol Zinc Ionophore for Terminating Advanced “Decreased Zinc” Testosterone-Dependent Prostate Cancer: A Case Report  

By medline, 1 week ago

  ABSTRACT In 2019, Costello et al. published the first successful treatment Case Report of a patient who presented with testosterone-dependent prostate cancer. That cancer is a “decreased-zinc” maligna...
medline RE: Pyrrolomycins Are Potent Natural Protonophores  

By medline, 1 week ago

Forum Just Science
  Potassium channel openers are uncoupling protonophores Excessive build-up of mitochondrial protonic potential is harmful to cellular homeostasis, and modulation of inner membrane permeability a pro...
medline Dipyridamole use is related to a lower risk of lymphoid neoplasms  

By medline, 1 week ago

Forum Lymphoma
  Summary The anti-cancer potential of dipyridamole has been suggested from experiments, but evidence from population-based studies is still lacking. We aimed to explore if dipyridamole use was related...
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