Lycopene --- Prosta...
 
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Lycopene --- Prostate Cancer


Kimster
(@kimster)
Joined: 1 year ago
Posts: 114
Topic starter  

Hi friends, just sharing the following "recent (year 2020)" review information:

 

https://www.sciencedirect.com/science/article/pii/S0753332220306521

Potential inhibitory effect of lycopene on prostate cancer

Available online 30 June 2020

 

Highlights

Lycopene is a natural, prominent, and effective product.
• We have studied about the anti-cancer, anti-progressive and apoptotic effects.
• Lycopene suppress the progression and proliferation.
• Lycopene arrest in-cell cycle, and induct apoptosis of prostate cancer cells.
• Lycopene could modulate the signaling pathways and their protein.

 

Abstract
Studying prostate cancer is important due to its high annual incidences and mortality rates in the world.
Although prostate cancer mortality rates are reduced using new therapy, complicated routes and side effects of these current drugs require a daily available treatment for prevention.
Lycopene is a natural, prominent, and effective product which has a high value in diet.
The anti-cancer effect, non-toxicity, safety and preventive or therapeutic roles of lycopene have been investigated in several studies.
In the current review, we have collected information about the anti-cancer, anti-progressive and apoptotic effects of lycopene on prostate cancer.
This article is a summary of the most important original and review articles on lycopene and its anticancer effects that are systematically categorized and presents information about the molecular structure, different sources, biological functions, and its in-vivo and in-vitro effects of lycopene on variety of cancerous and normal cells.
The clinical studies provide a clear image for continuous use of this adjunctive dietary for different type of cancers, especially prostate cancer in men.
In addition, this article discusses the various molecular pathways activated by lycopene that eventually prevent or suppress cancer.
Lycopene has been found to effectively suppress the progression and proliferation, arrest in-cell cycle, and induce apoptosis of prostate cancer cells in both in-vivo and in-vitro conditions.
Additionally, lycopene showed that it could modulate the signaling pathways and their protein for the treatment or prevention of prostate cancer.

 

 

Thanks.

Kimster


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Kimster
(@kimster)
Joined: 1 year ago
Posts: 114
Topic starter  

Also adding the following information for daily healthy diet:

 

https://www.eattobeat.org/evidence/295/natural-protection-against-prostate-cancer-in-tomato-sauce.html

Natural Protection Against Prostate Cancer in Tomato Sauce

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... a study conducted by researchers at the University of Illinois at Chicago suggests that the beneficial effects of lycopene on prostate health could be obtained by eating just one tomato-sauce based meal per day (3).

Tomato sauce is particularly rich in lycopene because it contains tomato paste, which has a high lycopene concentration.

There is also evidence that lycopene obtained from tomato sauce is better absorbed by the body than from whole tomatoes. 

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References

3.     Chen L, Stacewiz-Sapuntzakis M, Duncan C, Sharifi R, Ghosh L, van Breemen R, Ashton D, Bowen PE.  Oxidative DNA Damage in Prostate Cancer Patients Consuming Tomato Sauce-Based Entrees as a Whole-Food Intervention. J Natl Cancer Inst 2001, 93: 1872-9.

 

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https://www.eattobeat.org/food/1309/tomato.html

Food: Tomato

Scientific Name: Solanum lycopersicum ( alternative: Lycopersicon escultentum )

Natural Antiangiogenic Molecules:

Carotenoids (Lycopene),

Flavonoids (Naringenin, Quercetin, Kaempferol),

Alkaloids (Tomatine)

 

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Thanks.

Kimster


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Daniel
(@daniel)
Admin
Joined: 6 years ago
Posts: 1017
 

Thanks a lot @kimster!

Indeed, Lycopene is one of the top extracts relevant to prostate cancer. The best is to combine Lycopene with some oil to increase its absorption.

Kind regards,

Daniel

 


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