The Anti-Glioma Effect of Juglone Derivatives through ROS Generation
https://pubmed.ncbi.nlm.nih.gov/35774612/
(black walnut)
Synergistic effects of autophagy/mitophagy inhibitors and magnolol promote apoptosis and antitumor efficacy
Synergistic effects of autophagy/mitophagy inhibitors and magnolol promote apoptosis and antitumor efficacy
Chloroquine (autophagy inhibitor)
Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial. Median survival after surgery was 24 months for chloroquine-treated patients and 11 months for controls. https://www.ncbi.nlm.nih.gov/pubmed/16520474
Quercetin
and chloroquine synergistically kill glioma cells by inducing organelle stress and disrupting Ca2+ homeostasis
Alanine supplementation exploits glutamine dependency induced by SMARCA4/2-loss
https://www.nature.com/articles/s41467-023-38594-3
"supplementation of alanine restricts glutamine uptake through competition and selectively induces death in SMARCA4/2-deficient cancer cells."
Alanine supplementation exploits glutamine dependency induced by SMARCA4/2-loss
https://www.nature.com/articles/s41467-023-38594-3
"supplementation of alanine restricts glutamine uptake through competition and selectively induces death in SMARCA4/2-deficient cancer cells."
Alanine is suggested as an important ammonia-scavenging molecule.
Alanine supplementation exploits glutamine dependency induced by SMARCA4/2-loss
https://www.nature.com/articles/s41467-023-38594-3
"supplementation of alanine restricts glutamine uptake through competition and selectively induces death in SMARCA4/2-deficient cancer cells."
Alanine is suggested as an important ammonia-scavenging molecule.
gelatin (powder) is a good source of alanine and has no methionine.
