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Discovery shows how difficult-to-treat prostate cancer evades immune system

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Joined: 6 years ago
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“The findings open up potential new approaches to treating DNPC, which has been recognized recently as a new subtype that emerges at least in part in response to treatment with next-generation AR inhibitors,” said Giancotti, “We showed that PRC1 plays a role with immunosuppression at metastatic sites in DNPC, and we developed a novel in-class inhibitor of PRC1. This inhibitor exhibited efficacy as a single treatment and cooperated with double checkpoint immunotherapy to completely suppress metastasis in pre-clinical DNPC models.”

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Joined: 7 years ago
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Hi Johan,
Thanks for posting this it is always hopeful to see new and promising research being published.

johan and johan reacted