Posted by: @doctrlevine

Pic was too big, did not get uploaded.  Also earlier post should have said 8-12ml/day

ah, would love to see this.  thanks for the updates!

@doctrlevine

Thank you very much for update and sharing details.

I wish it will make positive impact. 

Do you intend to combine garlic with radiotherapy to synergize  garlic's immunomodulation with radiotherapy induced immune system stimulation?

And if so do you plan to schedule garlic applications day after the radiotherapy to avoid anti-oxidant effect of garlic on radiotherapy?

Kind Regards

Asaf

@asafsh

At this point, there is no radiotherapy, either EBRT or SBRT expected in the foreseeable future.  My wife had 7 fractions of SBRT,  treating her 3 areas of mets. around a month ago.  The RGE at 1:1 with DMSO, is working out fine.  We are primarily trying to avoid chemo.  She had blood work last week and her CEA was wnl and CA19-9 was almost there.  Liver enzymes slightly elevated, due to SBRT, nothing to worry about.  We would like to see the LDH continue to drop.  If the trend continues down, no chemo.

The pic is 2.4 MB.  File size that is allowed is up to 10MB, but when I try and upload, it posts the written message but not the pic, saying file size is too large.  Also, how can I delete a message after posting?  No need to have a list saying here's the pic, and there's nothing shown

@doctrlevine

Hi Nuc, 

It should work to add the pic. If not, please send it to me by e-mail and I will add it. If not, I will erase the post above so that is not left without the pic.

Users can delete or edit own posts for 5 min after publishing that. After that only the admin (me in this case) can edit comments. Whenever, you need to change something after the 5 min, just let me know.

Kind regards,

Daniel

@doctrlevine

You may try to resize the picture let say by 1/2 by Paint program, that will decrease its size 4 times.

trying again, maybe from the desktop will work

@doctrlevine

thank you for posting this picture, Nuc! And your wife's markers are improving, really wonderful!

Hey nuc i just wanna help you somehow i read a lot and collect info about the strongest foods that can cure pretty much anything so i share it with you maybe it will help

eat one bulb a day yest bulb xd 

one bulb with 2liter water you can also add there lemon

suck one glove of garlic 3 times a day in sublingual way 30 min

 also try turmeric + black pepper and ggarlic

green tea + black pepper

Nuc how is your wife is garlic injection worked?

Hi Nuc,

what happens to your wife? hopefully she OK ? 

Please update

Thank you

Hello, 

I am interested in leaning more about this as I have been diagnosed with a similar condition.

@doctrlevine

Hi Nuc.  My son was diagnosed stage 4 duodenal adenocarcinoma in March.  He's doing chemo and a number of metabolic therapies (IVC, mistletoe, supplements, fasting, diet).  I am very interested in IV or subcutaneous RGE and don't know how to go about it.  Would you be willing to talk with me via email?

Thanks for considering.

Posted by: @aspek

Hello all,

 

I wanted to share some of my data collecting about this quite interesting plant.

 

Regarding cancer, garlic seems to fight on multiple fronts:

 

 

 

 

 

Warning:

According to the stoputiforever.com the lowest toxicity dose associated with garlic was 400mg/kg.

Also garlic affect the coagulation, so even with just eating garlic if you take Warfarin there is a danger of combined effect and consequentially danger of internal bleeding. 

 

I would be really happy to hear comments from you and a discussion how to possibly apply this information to cancer treatments. 

 

Anyway it seems to me that with the garlic we cannot make a mistake.

 

Hi friends, just would like to share the following information here:

https://www.sciencedirect.com/science/article/pii/S0753332219353521

Phytochemicals of Garlic: Promising Candidates for Cancer Therapy

March 2020

Thanks.

Kimster

Hi friends, just sharing the following information here after just read it:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073756/

Allicin Bioavailability and Bioequivalence from Garlic Supplements and Garlic Foods

2018

5. Conclusions

The bioavailability of allicin from garlic powder supplements containing alliin and active alliinase can be as high as that from an equivalent amount of crushed raw garlic containing maximum allicin, when consumed with a meal.

This was found to be true for all tested brands of normal (non-enteric) tablets, including the main garlic powder supplement, Kwai (N1), which has been used in a large number of clinical trials on the possible health benefits of garlic and validates the results of these trials as representing about 1 g of crushed raw garlic.

Compared to non-enteric tablets, allicin bioavailability from enteric tablets was found to be much more variable (36–104%) and to be strongly reduced (22–57%) when consumed with a high-protein meal, due to delayed gastric emptying. 

:

Based on the allicin metabolite equivalence found for the 13 garlic powder supplements tested, a person would need to consume 0.7 to 27 tablets/capsules to obtain the same equivalence as consuming 2 g of crushed raw garlic;

however, the recommended daily dose by the supplement manufacturers varied from 1–6 tablets/capsules per day, highlighting the need for more complete standardization.

With a more correct understanding of allicin bioavailability, better standards are now being recommended for garlic powder supplements being used in future clinical trials and being consumed by the general public, which standards include a dosage form with sufficient allicin bioavailability and alliin content or allicin potential to represent a daily dose of 2–4 g of typical crushed raw garlic.

Thanks.

Kimster

Posted by: @kimster

Hi friends, just sharing the following information here after just read it:

 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073756/

Allicin Bioavailability and Bioequivalence from Garlic Supplements and Garlic Foods

2018

 

5. Conclusions

The bioavailability of allicin from garlic powder supplements containing alliin and active alliinase can be as high as that from an equivalent amount of crushed raw garlic containing maximum allicin, when consumed with a meal.

This was found to be true for all tested brands of normal (non-enteric) tablets, including the main garlic powder supplement, Kwai (N1), which has been used in a large number of clinical trials on the possible health benefits of garlic and validates the results of these trials as representing about 1 g of crushed raw garlic.

Compared to non-enteric tablets, allicin bioavailability from enteric tablets was found to be much more variable (36–104%) and to be strongly reduced (22–57%) when consumed with a high-protein meal, due to delayed gastric emptying. 

:

Based on the allicin metabolite equivalence found for the 13 garlic powder supplements tested, a person would need to consume 0.7 to 27 tablets/capsules to obtain the same equivalence as consuming 2 g of crushed raw garlic;

however, the recommended daily dose by the supplement manufacturers varied from 1–6 tablets/capsules per day, highlighting the need for more complete standardization.

With a more correct understanding of allicin bioavailability, better standards are now being recommended for garlic powder supplements being used in future clinical trials and being consumed by the general public, which standards include a dosage form with sufficient allicin bioavailability and alliin content or allicin potential to represent a daily dose of 2–4 g of typical crushed raw garlic.

 

Thanks.

Kimster

 

 

 

 

 

Hi friends, just adding similar information here:

https://nutritionfacts.org/video/benefits-of-garlic-for-fighting-cancer-and-the-common-cold/

Benefits of Garlic for Fighting Cancer and the Common Cold

Daniel,

I am trying to figure out the dose for RGE for my son, who is 72kg.  The mouse dose is 1ml RGE to a 15g mouse according to Zheng Cui's paper.  I've read an article on how to convert animal dose to human equivalent dose, but it seems to be way too high (392ml).  Can you help me figure out the HED?  It looked like Nuc had figured out the math.  My plan would be to deliver intravenously via 500cc bag of normal saline.

My son was diagnosed with stage 4 duodenal adenocarcinoma in March 2020 and made amazing progress on chemo, IVC, IV mistletoe, fasting, paleo diet, supplements.  The main tumor and all mets disappeared but, recently, bone mets are back.  We took chemo down to 60% at round 11 but I don't think that was low enough.  Probably should have been at metronomic dose (10-30%).  We are now considering the addition of RGE and hyperthermia.  Would love to know how others have done with RGE.

Thanks for your help.

Matt

@mattbrown2

Dear Mat,

I have no references on its use as IV in humans. If I find the time, I will check the literature for that.

In order to convert doses from animals to humans here are the formulas that are typically used https://www.researchgate.net/profile/Bai-Yan_Li/post/Studies_in_antidiuretic_papers_show_the_dose_used_for_HCTZ_is_10_mg_kg_in_a_rat_If_I_use_furosemide_then_what_will_be_the_equivalent_dose_for_a_rat/attachment/59d629fec49f478072e9c9a2/AS:272424950534145@1441962577658/download/ACUC42-1.pdf

Do you have any reference point on doing RGE in humans, in terms of source, dose and formulation for IV?

Kind regards,
Daniel

@daniel

Daniel,

Thank you for your amazingly quick response.  I am attaching a patent for the delivery of RGE via IV.  It provides dosing information (.065g of RGE per kg of body weight).  For most people this equates to 5g, which gets put into a 500cc bag of normal saline.

https://patents.google.com/patent/US8778421B1/en

It appears that creating the juice by blending and then centrifuge (per Zheng Cui's paper) are best done in cold conditions.  I'm thinking storing the RGE in dry ice or the freezer.

Any additional thoughts will be most appreciated.

Blessings,

Matt

@mattbrown2

Hi Matt,

Thank you! I will check asap and let you know what I think.

Kind regards,
Daniel

@daniel

Daniel,

I have found good information regarding raw garlic's anti-cancer properties, the ability to deliver it via IV, some reasonable dosing guidelines, its relative benignity, and excellent performance on mice (Cui study).  The one thing I lack is information on how it is performing on people with cancer.  I have spoken with an integrative oncologist who said that, in China, he used it for leukemia and, while it was not a silver bullet, he sees it as a good adjuvant.

Do you have any information on how RGE has worked for people with different types of cancers?  I'm having a hard time finding this kind of data.  If you are aware of any information along these lines, would greatly appreciate seeing it.  Thank you for all that you do.

Matt

@mattbrown2

Dear Matt,

I do not have info on RGE used in humans with positive results, but if there is any, I am very good at fining it. These days I was, and I am extremely busy with a lot of requests for help on the email and a lot of work on MCS Formulas. As soon as I get more time for research I will look into RGE.

For IV, I would probably look for DMSO/water and/or ethanol/water extracts (to be sterilized and used) or if there is any issue with specific compounds from the whole plant extract (for IV delivery) I would just select the main ingredients expected to induce the anti cancer effects, such as allicin and convert it into an injectable form, probably with a little kolliphor.

Please remind me again to look into it.

Kind regards,

Daniel

@mattbrown2

Hi Matt, 

I am in a similar situation and hopping to learn from others in the group....  Please let us know of any progress you have made and I hope your son is doing well....

G.