https://www.clinicaloncology.com/Solid-Tumors/Article/10-19/DoseReduced-Chemo-Effective-in-Elderly-Patients/56308

"When compared with patients who received the regimen only at full doses, the patients given reduced doses had better overall survival. Patients who underwent at least one dose reduction had a median survival time of 9.27 months (95% CI, 7.23-11.30), versus 4.37 months (95% CI, 1.13-7.60) in patients who did not undergo dose reductions. “We assume this was due to less toxicity with dose reductions”