hello daniel would you have any opinion about the use of granulocyte colony stimulants before radiotherapy sessions? and in general about the protocol I know that it is very difficult to look at everything in depth but an idea at hand.
kind regards
Hi Marcos,
I looked at your document and I think the following are the priorities during radio:
1. pro-oxidant treatment
2. ATP depletion
3. pH
4. authophagy
I think you are addressing most well. Just a few comments:
- In order to further improve #1 I would consider the addition of Auranofin, and maybe Paracetamol prior to radio.
- In order to further improved #2 I would consider Ritonavir https://www.cancertreatmentsresearch.com/drugs-and-supplements-that-block-fermentation-and-help-fight-cancer/
- In order to address the possible Treg upregulation, I would consider Cimetidine if possible
- I would probably use Basentabs to alkalise the space and maybe some mushrooms to increase the immune activity.
- btw, Salinomycin may add good value if done day e.g. 3, 5, 7
In contrast to chemotherapy, for radio therapy I would continue the use of fermentation inhibitors also prior to the intervention, i.e. no restriction as long as they are not anti-oxidants.
Good luck, and a lot of prayers for your success. If there is any question, please let me know and I will react asap.
Kind regards,
Daniel
HI Marcos,
In addition to the above, I will send you by e-mail a picture that may be useful on the pro-oxidant strategy I am working on.
Kind regards,
Daniel
thanks daniel for your kindness as always, i will implement paracetamol and i will put intravenous salinomycin on days 1,3 and 5 because it will be only 5 sessions of radiotherapy.as for auronafin i couldn't find it in spain and i don't have time to buy it anymore.ritonavir i think it interferes with some of the medicines of intracellular acidification.you would have an opinion about granulocyte stimulating colonies,I have seen contradictory studies.
I had also thought about cimetidine, but I will probably soon start immunotherapy with lenvima + pembrolizumab and according to Dr. Jason w antibiotics would reduce the chances of success of immunotherapy.
Hi Marcos,
You are very welcome! If you do not have a good feeling about granulogyte stimulating, I would just not go with that. Cimetidine is not an antibiotic so it should not be an issue and it should also help immunotheraphy. However, Salinomycin is an antibiotic!
Kind regards,
Daniel
Of course, in the drawing you sent me, there is the intravenous vitamin C, but I think it should be stopped before the radiotherapy, because I am not sure about its pro-oxidant action either.
First of all, i want to say thank you for the clinic info Daniel, i´m going to email him this week to know if it´s possible to be their patient
Daniel as i´m waiting a second opinion from another hematologist i started the recommendations that we can fin in shutting Downd the Power House of cancer. I have a positive feeling after completing the drugs that are in that thread, waiting for receiving HCA .Can you please give your opinion if it´s a possible a good addition to take the artemisin and artemisia Annua protocol with them?
Marcos, i have been searching how to find Auranofin and Ritovanir in Spain or Europe. Very hard for me, so if you find a source, could you share it, please? Wishing the best Marcos
warm regards
Inaki
I wanted to say exactly what you have said that salinomycin is an antibiotic and that I will implement cimetidine, between the nerves and the little knowledge of the language sometimes I confuse the terms
Great! As you know, and just as a reminder, just check the interaction of Cim in case you use e.g. hormonal treatments.
i checked in a pharmacy that helps me and they can not bring it, they told me maybe it´s something used only by hospitals 🙁
Dear @daniel
Please when you have some time, can i know your thoughts of my planning to start the radiotherapy treatment in about 15 days? After several appointments with my doctors i have agreed to try it as it´s going to be very very local and no big intensity as i tell him that i´m going to try to enhance it´s effects. We want to try the small spot with this, and save nivolumab for the future, as i can´t travel because of Cod …
Well , it´s going to be 20 sessions, so 5 days per week.
I plan to take :
- 50 mg of DHEA daily in the morning. Would you take 50 or 100 mg?
- Paracetamol each day before the Radio days
- I have sulphasalazine 500 at home, how much would you take daily? As lowers gluthatione would you take the first dosage before the radio time? For example 1000 for breakfast and 1000 with the dinner?
- Amiloride 5 mg daily only the 5 days per week radio days
- Acetazolamide 250mg/day . Is a enough dosage?
- 3 caps Basentabs daily
- 400 x 2 cimetidine
- 3 caps daily of Ellagic, 500 mg 60 caps - Ecological Formulas
- 300mg daily of Canagliflozin , 500 mg of metformin and 500 mg of berberine. Would you up metformin and take the berberine down?
- High omega 3 dosage daily
- 4 days on and 3 off Artemisinin protocol, that includes artemisinin supplement and 5 gr of whole plant powder
- 3x Swason apigenin 50 mg capsules + fresh/dried parsley daily during the all radio month
- Broccoli sprouts and broccomax daily during the all radio month
- 250 x 2 Atovaquone and 200 of hydroxychloroquine all radio month
- Prebiotic fiber +home saukekart+ home kéfir all radio month
- Zinc gluconate supplement all radio month
- Lansoprazol all days before the radio time
- Daily aspirin 100 mg at night
- Would you take 50 – 100 of diclofenac?
- Rectal ozone to help with the oxygenation
- After one week of finishing the radio liposomal quercetin, honokiol, curcumin
Kind regards
Inaki
Dear @daniel
Please when you have some time, can i know your thoughts of my planning to start the radiotherapy treatment in about 15 days? After several appointments with my doctors i have agreed to try it as it´s going to be very very local and no big intensity as i tell him that i´m going to try to enhance it´s effects. We want to try the small spot with this, and save nivolumab for the future, as i can´t travel because of Cod …
Well , it´s going to be 20 sessions, so 5 days per week.
I plan to take :
- 50 mg of DHEA daily in the morning. Would you take 50 or 100 mg?
- Paracetamol each day before the Radio days
- I have sulphasalazine 500 at home, how much would you take daily? As lowers gluthatione would you take the first dosage before the radio time? For example 1000 for breakfast and 1000 with the dinner?
- Amiloride 5 mg daily only the 5 days per week radio days
- Acetazolamide 250mg/day . Is a enough dosage?
- 3 caps Basentabs daily
- 400 x 2 cimetidine
- 3 caps daily of Ellagic, 500 mg 60 caps - Ecological Formulas
- 300mg daily of Canagliflozin , 500 mg of metformin and 500 mg of berberine. Would you up metformin and take the berberine down?
- High omega 3 dosage daily
- 4 days on and 3 off Artemisinin protocol, that includes artemisinin supplement and 5 gr of whole plant powder
- 3x Swason apigenin 50 mg capsules + fresh/dried parsley daily during the all radio month
- Broccoli sprouts and broccomax daily during the all radio month
- 250 x 2 Atovaquone and 200 of hydroxychloroquine all radio month
- Prebiotic fiber +home saukekart+ home kéfir all radio month
- Zinc gluconate supplement all radio month
- Lansoprazol all days before the radio time
- Daily aspirin 100 mg at night
- Would you take 50 – 100 of diclofenac?
- Rectal ozone to help with the oxygenation
- After one week of finishing the radio liposomal quercetin, honokiol, curcumin
Kind regards
Inaki
Hi Inaki,
1. I would also include Polydatin here and reduce DHEA to half
3. In a recent clinical trial they use at 3g/day, 3 days prior to radio https://clinicaltrials.gov/ct2/show/NCT04205357
5. acetozolamide dose was discussed here https://www.cancertreatmentsresearch.com/ph-cancer-a-top-treatment-strategy/ for more details you may want to contact the expert https://salvadorharguindey.blogspot.com/p/salvador-harguindey.html
7. check the interaction of Cim with others
9. No because you already have Atorvaqone as mito inhibitor
19. Only if possible because you already are using a lot of drugs
Please take care as you are taking a lot of drugs. Make sure you have assistance of a medically trained person while on Amiloride and acetozlamide, as they may lead to increase of blood potassium level which can be dangerous.
Kind regards,
Daniel
Good night Daniel,
Can i ask you your opinion about the best Nsaid to take during the Radiotherapy?
If you could choose among;
Flarin (liposomal ubuprofen) 400 x 3 daily as coc suggests
Diclofenac 200 - 300 mg during the day . I ask this because i can help to block mct1 + COX
Celecoxib 100 x 3 daily
¿Aspirin?
Would you take liposomal quercetin 1 hour before the R daily season and another one in the afternoon ?
An the last one, as you speak about sulforaphane before and during the Radiotherapy . Is good enough take it from broccoli sprouts or would you add Broccomax for example?
I wish you are fine with this pandemic
Warm Regards
Inaki
Good night Daniel,
Can i ask you your opinion about the best Nsaid to take during the Radiotherapy?
If you could choose among;
Flarin (liposomal ubuprofen) 400 x 3 daily as coc suggests
Diclofenac 200 - 300 mg during the day . I ask this because i can help to block mct1 + COX
Celecoxib 100 x 3 daily
¿Aspirin?
Would you take liposomal quercetin 1 hour before the R daily season and another one in the afternoon ?
An the last one, as you speak about sulforaphane before and during the Radiotherapy . Is good enough take it from broccoli sprouts or would you add Broccomax for example?
I wish you are fine with this pandemic
Warm Regards
Inaki
HI Inaki,
I understand that point 1 is addressed.
Regarding Quercetin and Sulforaphane, the answers are in the article I recently published https://www.cancertreatmentsresearch.com/modulating-the-yin-and-yang-energy-of-cells-to-fight-cancer-pro-oxidant-strategy/
More specifically, I did not included Sulforaphane in there. That means that if taken, it should be taken some days after pro-oxidant treatments. Following some more discussions on this subject, I also recently added a remark on the fact that maybe even for the supplements that we know have pro-oxidant effects such as Quercetin and Curcumin, it still makes sense to wait a few days.
So in the end I think this is what makes sense:
- strong anti-oxidants like NAC, ALA, etc. should not be taken 6-7 days before and after chemo
- anti-oxidants known to have pro-oxidant effects (like Quercetin, Curcumin, etc.) should not be taken 2-3 days before and after chemo
- pro-oxidants or others widely known to bring good benefit to radio/chemo can be continued during chemo/radio. Examples are: Omega 3, Aremisia Annua, Silver.
There is a point related to Arte reacting with Iron that may be not the best when taken after induced tumor necrosis. But I am not sure of the level of relevance o this point.
I hope this helps.
Kind regards,
Daniel
I guess you've already discussed the possibility of radiotherapy triggered 'hot tumor' transformation for Hodgkin lymphoma along with pdl checkpoint inhibitors.
probably that was postponed as Nivolumab isn't used in this step.
may be green tea extract (at max doses) can do the same job (possibly lesser efficacy) ????
https://www.mdpi.com/1420-3049/23/8/2071
iirc, if adding that approach to present strategy is relevant, the radiotherapy dose and administration schedule might need to be re-evaluated.
p.s.
btw, is the co-administration of 2 NSAIDs at the same OK(aspirin and diclofenac)? I'd been told to not to do that.
Good night !
Thank you for your idea, my problem is as always that doctors don't never consider to mix another ideas as they protocol, so what can i do is try to try to do their treatment more effective ...
But what it's quite probable that EGCG in high oral dosage looks to work nicely with pro-oxidants treatments as radio or chemo, but unfortunately we still can´t be 100 sure ...
i have at home febendazole, mebendazole and niclosamide. Please, can i know if you find any of them a good drug during Radiotherapy weeks?
If you have to choose one in this context, what would you use between Acetazolamide or amiloride?
Do you find that apigenin extract and ellagic acid are best take out the radio weeks as curcumin, quercetin,...?
Warm regards
Thank you, once again
Inaki
Hi Inaki,
1. febendazole, mebendazole and niclosamide - I like all of them - I would pick one that was not used before, in order to cycle
2. Acetazolamide or amilorid - I would go for Amiloride but you need to have support to follow potassium levels every two weeks and make sure it's in a safe range
3. apigenin extract and ellagic acid - in general, I would follow this rule that I recently added here to make things a little more simple:
- strong anti-oxidants like NAC, ALA, etc. should not be taken 6-7 days before and after chemo;
- anti-oxidants known to have pro-oxidant effects (like Quercetin, Curcumin, etc.) should not be taken 2-3 days before and after chemo
- pro-oxidants or others widely known to bring good benefit to radio/chemo can be continued during chemo/radio. Examples are: Omega 3, Aremisia Annua, Silver Solution
Apigenin and Ellagic acid, go in the second group. Apiginin for example is also known to modulate NRF2 anti-oxidant master regulator.
Kind regards,
Daniel
Hello Daniel,
Wishing you are healthy and doing well lately . I hope to buy from you my supplements soon 🙂
I would like to ask your point of view to make a meaningful strategy regarding the plan to do 4 sessions of vitamin C IV per week (before the Pet scan to evaluate if i got remission after my radiotherapy sessions), regarding drugs and supplements that are interesting to co-administer:
I will leave the extracts and supplements that I take now:
2.5 gr of egcg
8 g of c3 complex
20 ml of liposome quercetin
250 x 2 R lipoic acid de life extension
I have decided and wanted to know your opinion about
Support sessions with liposomal vitamin C during the day
Continue taking berberine or metformin but after a time of finishing the IV C session. Which one do you prefer? Stop de the day before the first infusion
.Take Canagliflozine
Zinc gluconate
DHEA
HIGH OMEGA 3 and seabuckthorn
RECTAL OZONE
Continue taking Ldn
Take Atovaquone
Baby Aspirin
Amiroride for the 2-3 weeks on IVC, checking the pottasium levels in blood
Milk thiste to support liver as aways do
With the Radiotherapy I took Sulfazasizine, do you think that it fits well to take it during IV days)?
After 12 days of radio I started a batch of Doxycilline and I continue taking it for 15 days. Maybe it's the question I have, keep taking it? Stop the day before and during the weeks with IVC? I also have access to azithromycine in case it is a better option
Warm regards
Inaki
Hi Inaki,
Thank you, I wish you a lot of heath and happiness too. Regarding buying supplements from MCS Formulas, just do what you think and feel it's best.
Regarding your questions, I am not sure I understand correctly, but here is my response based on what I understand:
You will are now taking Curcumin, EGCG, RLA, Quercetin. I like all of them but I would stop RLA during the intensive High dose Vitamin C treatments. Or you are stopping all of them?
Supporting with liposomal C may help and to that I would also add normal Vitamin C as discussed here (since they are absorbed in a different way) https://www.cancertreatmentsresearch.com/community/postid/2747/
On the question "Continue taking berberine or metformin but after a time of finishing the IV C session." - both Berberine and Metformin.
You are now taking Canagliflozine, DHEA, Omega 3, Ozone, LDN, Atorvaquone, Aspirin, Amiloride, Milk Thisle. To support Vitamin C, I specifically like DHEA, Omega 3 from all these.
Canagliflozine, maybe it's best to stop during the high dose Vitamin C cycles (Ascorbic acid, a reduced form of vitamin C, or glucose enters cells specifically through SVCT or SGLT, while Dehydroascorbic acid, an oxidized form of vitamin C, enters or exits cells competitively with glucose through facilitative glucose transporters (GLUTs)).
Because of this reason, talking Metformin and Berberine to reduce blood glucose level should help increase the absorption of Ascorbic Acid and DHA by cancer cells. So I would take them both before and after Vitamin C intravenous.
Amiloride should work well with Atorvaquone.
Sulfazasizine should help Vitamin C effectiveness.
Please check my post on PRO-OXIDANT therapy and consider finding a clinic that can administer EDTA prior to Vitamin C intravenous. That may increase the effectiveness of Vitamin C.
As you know combining high dose Vitamin C with Doxy and azithromycine may help. Combining these would be more along the "Shutting Down the Power House of Cancer cells strategy" while combining Vitamin C with Sulfasalazine, DHA, Omega 3, etc, would be more along "Pro-Oxidant strategy".
Using Amiloride in combo with Metformin and Doxycicline would be more along "pH strategy".
I like all of them, but if High Dose Vitamin C intravenous is your core treatment, make sure you build as much around that as possible. In order to do this I would first think what are the major anti-cancer mechanisms behind Vitamin C.
There are two major ones in my view:
- pro-oxidant effects due to production of hydrogen peroxide that will interact with Iron
- glycolisis inhibition
Therefore, the strategies we implement should be aligned with the above two mechanisms. As a result, I would give priority to the following strategies (and related drugs and supplements) in this specific case:
1. Pro-oxidant support
- Use ways to increase the availability of labile Iron pools (using treatments such as EDTA prior to Vitamin C)
- Use ways to support the pro-oxidant action by reducing anti-oxidants and increasing pro-oxidants as discussed here https://www.cancertreatmentsresearch.com/modulating-the-yin-and-yang-energy-of-cells-to-fight-cancer-pro-oxidant-strategy/ You already mentioned a few such as DHEA, etc.
2. Maximise the outcome of glyco inhibition by integrating Vitamin C with the following strategy https://www.cancertreatmentsresearch.com/shutting-down-the-power-house-of-cancer-a-strategy-to-fight-cancer/ You already mentioned a few
I would give priority to #1 and if there is space for more drugs and supplements I would implement #2. And if these are done well and there is still more space for supplements and drugs, I would move to pH strategy (that includes Amiloride that you mention you are using).
I hope this helps and answers your question.
Kind regards,
Daniel
Dear Daniel,
I want to start by sharing that yesterday I received the great news of a clean Pet-Scan, so imagine my joy and my thanks to your suggestions to support Radiotherapy and then collecting the information that exists on the website to improve IV C by doing it myself same with the help of a nurse after finishing the Radio ...
Also congratulate you for the supplement company, I already made a first order and soon I will have to make a second, since I want to contribute my money to this project and that they are products not available in Spain.
I would like to ask for your opinion on how to try to improve the following issues that seem important to me to correct:
The first of them is that I have accumulated a low percentage of lymphocytes after illness and toxicity, and I need to improve the balance between Neutrophils - lymphocytes…
For this I had thought about using the mistletoe for a while to see if it can help me. What do you think of using it for this purpose? Reviewing your article on mistletoe I have the doubt if any of this list could come better to me https://www.medizinfuchs.de/Iscador%2BP.html?sac=1
Or if any of the series that would be more suitable
https://www.medizinfuchs.de/Iscador%2BQu.html?sac=1
I´m taking more of sauerkraut, kéfir, miso, ...
I am also using extracts of Cordyceps and Reishi… Do you have any other suggestions that can help me with this problem?
The other question is similar, in this case trying to improve hemoglobin:
I have low levels of ferritin and iron, in addition that the use of high doses of mugwort, turmeric, vitamin C do not help improve reserves, so I am taking Floradix and life extension lactoferrin to gradually recover this deficiency ...
I have also used high doses of zinc gluconate, and I think that perhaps the copper is also rather low but I suppose it is better not to think about supplementing it and if perhaps I should stay a more moderate dose of zinc ...
Apart from this, would you add the Maitake extract? I have read that the root of suma can help the bone marrow to partially recover its functions after toxicity. Would you use any other extract or supplement for this purpose?
Do you think it is a good idea to incorporate such a multivitamin?
https://www.healthleadsuk.com/supplements/vitamins/multi-vitamin-complex-585mg-x-90-capsules.html
In turn, I have finally gotten medication to make a transition from levothyroxine to liothyronine T3, as it seems clear that it has its positive impact on cancer ...
A hug,
Sincerely
Iñaki
Dear Inaki,
Thank you for letting us know about such a great news! Clean PET-CT sounds perfect!!!
Are you doing the intravenous Vitamin C at home now?
Thank you so much with the support to MCS Formulas and for being one of our first customers! I very much appreciate that and I will do my best to help as much as I can.
Regarding Lymphocytes, Vitamin C that you are already using should help:
Influence of Vitamin C on Lymphocytes: An Overview https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874527/
The Effect of Vitamin C (Ascorbic Acid) in the Treatment of Patients with Cancer: A Systematic Review
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566697/
Maitake beta-glucan promotes recovery of leukocytes and myeloid cell function in peripheral blood from paclitaxel hematotoxicity https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268513/
Maitake Beta-Glucan MD-fraction Enhances Bone Marrow Colony Formation and Reduces Doxorubicin Toxicity in Vitro https://pubmed.ncbi.nlm.nih.gov/14975363/?dopt=Abstract
Gelum Drops: reducing lactic acid, increasing hemoglobin and lymphocytes https://www.cancertreatmentsresearch.com/gelum-drops-reducing-lactic-acid-increasing-hemoglobin-and-lymphocytes-2/
Barely Grass is one of the best instead of multivitamins and for anemia https://www.hindawi.com/journals/omcl/2018/3232080/
Angelica sinensis, commonly known as dong quai or female ginseng, found as a supplement online
Acidic Polysaccharide from Angelica sinensis Reverses Anemia of Chronic Disease Involving the Suppression of Inflammatory Hepcidin and NF-κB Activation https://www.hindawi.com/journals/omcl/2017/7601592/
Experimental study of Angelica sinensis polysaccharide-iron complex on rats with iron deficiency anemia http://europepmc.org/article/CBA/639443
Angelica sinensis, the most important herb in Dang-Gui-Bu-Xue decoction, could increase the quantity of red blood cells (RBCs), white blood cells (WBCs) and bone marrow nucleated cells (BMNCs), promote the proliferation of BMNCs and increase the quantity of multilineage progenitor cells (CFU-Mix) in a mouse model [10]. Previous studies have also shown that Angelica sinensis polysaccharide (ASP) can protect the hematopoietic function of CD34+ cells against adriblastin [11], improve the hematopoietic function of CD34+ hematopoietic stem/progenitor cells (HSPCs) by mitigating oxidative damage to stromal cells [12], and protect against X-ray irradiation-induced aging by inhibiting oxidative stress damage [13]. In addition, ASP promotes hematopoiesis and thrombopoiesis through the PI3K/AKT pathway [14]. We also confirmed the effect of ASP on mitochondrial membrane stabilization in another AA model by evaluating the number of mitochondrial, and concentration time curves of COX and MDH [15]. However, the anti-apoptotic function of ASP remains unknown. https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-020-02995-4
I would not go for mistletoe in your case, because that can trigger inflammation and that is not what you need specifically at this point, in my view.
Instead, I would focus on anti-inflammatory drugs and supplements.
Because of the reasons above I would indeed, consider adding Maitake.
Instead of multivitamin, I would use Barely Grass and try to take them from diet.
Great to hear that you are now on T3 instead of T4!
I am very happy for you Inaki! Take care of you!
Kind regards,
Daniel
Dear Daniel,
I want to start by sharing that yesterday I received the great news of a clean Pet-Scan,
...
Sincerely
Iñaki
That's wonderful news, Iñaki! Congrats, and well done!!!
Thank you @johan .
I always read your posts too, i like your info and recently i found your blog and it´s great too!
I´d like to rotate many antiviral herbs in my new "protocol": i have thought in andrographis , chaparral, pau de arco, cat´s claw, anamu, olive leaf, oregano oil, licorice root, Scutellaria baicalensis ordered from mcs,
Do you miss any other herb? I´m thinking to choose 2-3 and take them for three weeks and rest and restart with another 2-3 three weeks ... And the rest week colloidal silver for example
I also wonder if it's good idea to take one of them without breaks 🙂
Have a good Weekend
Inaki
I´d like to rotate many antiviral herbs in my new "protocol": i have thought in andrographis , chaparral, pau de arco, cat´s claw, anamu, olive leaf, oregano oil, licorice root, Scutellaria baicalensis ordered from mcs,
Do you miss any other herb? I´m thinking to choose 2-3 and take them for three weeks and rest and restart with another 2-3 three weeks ... And the rest week colloidal silver for example
I also wonder if it's good idea to take one of them without breaks 🙂
I believe it's a good idea to rotate herbs and supplements, Iñaki, the herbs you mention are wonderful antiviral/anticancer;curcumin and black cumin seed taken together also appear to be an effective antiviral combination( https://www.researchgate.net/publication/297129196_Synergistic_effects_of_thymoquinone_and_curcumin_on_immune_response_and_anti-viral_activity_against_avian_influenza_virus_H9N2_in_turkeys )
Have a great weekend!
Dear Inaki,
Thank you for letting us know about such a great news! Clean PET-CT sounds perfect!!!
Are you doing the intravenous Vitamin C at home now?
Thank you so much with the support to MCS Formulas and for being one of our first customers! I very much appreciate that and I will do my best to help as much as I can.
Regarding Lymphocytes, Vitamin C that you are already using should help:
Influence of Vitamin C on Lymphocytes: An Overview https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874527/
The Effect of Vitamin C (Ascorbic Acid) in the Treatment of Patients with Cancer: A Systematic Review
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566697/Maitake beta-glucan promotes recovery of leukocytes and myeloid cell function in peripheral blood from paclitaxel hematotoxicity https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268513/
Maitake Beta-Glucan MD-fraction Enhances Bone Marrow Colony Formation and Reduces Doxorubicin Toxicity in Vitro https://pubmed.ncbi.nlm.nih.gov/14975363/?dopt=AbstractGelum Drops: reducing lactic acid, increasing hemoglobin and lymphocytes https://www.cancertreatmentsresearch.com/gelum-drops-reducing-lactic-acid-increasing-hemoglobin-and-lymphocytes-2/
Barely Grass is one of the best instead of multivitamins and for anemia https://www.hindawi.com/journals/omcl/2018/3232080/
Angelica sinensis, commonly known as dong quai or female ginseng, found as a supplement online
Acidic Polysaccharide from Angelica sinensis Reverses Anemia of Chronic Disease Involving the Suppression of Inflammatory Hepcidin and NF-κB Activation https://www.hindawi.com/journals/omcl/2017/7601592/
Experimental study of Angelica sinensis polysaccharide-iron complex on rats with iron deficiency anemia http://europepmc.org/article/CBA/639443Angelica sinensis, the most important herb in Dang-Gui-Bu-Xue decoction, could increase the quantity of red blood cells (RBCs), white blood cells (WBCs) and bone marrow nucleated cells (BMNCs), promote the proliferation of BMNCs and increase the quantity of multilineage progenitor cells (CFU-Mix) in a mouse model [10]. Previous studies have also shown that Angelica sinensis polysaccharide (ASP) can protect the hematopoietic function of CD34+ cells against adriblastin [11], improve the hematopoietic function of CD34+ hematopoietic stem/progenitor cells (HSPCs) by mitigating oxidative damage to stromal cells [12], and protect against X-ray irradiation-induced aging by inhibiting oxidative stress damage [13]. In addition, ASP promotes hematopoiesis and thrombopoiesis through the PI3K/AKT pathway [14]. We also confirmed the effect of ASP on mitochondrial membrane stabilization in another AA model by evaluating the number of mitochondrial, and concentration time curves of COX and MDH [15]. However, the anti-apoptotic function of ASP remains unknown. https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-020-02995-4
I would not go for mistletoe in your case, because that can trigger inflammation and that is not what you need specifically at this point, in my view.
Instead, I would focus on anti-inflammatory drugs and supplements.
Because of the reasons above I would indeed, consider adding Maitake.
Instead of multivitamin, I would use Barely Grass and try to take them from diet.
Great to hear that you are now on T3 instead of T4!
I am very happy for you Inaki! Take care of you!
Kind regards,
Daniel
Hi @daniel,
Thank you for your suggestions, i'm going to add many of them to try to up Hb and avoid for the moment to use the mistletoe as you mention the inflammation issue ... 🙂
I´d like to share with you what i´m taking because i´d like still todo a extensive protocol as my lymphoma has been tough and rebellious during these last ten years. So, I would consider still do a powerful approach in this NED status:
I daily take :
- First thing in the morning, rectal insufflation ozone
-Inflammation: Olive leaf, Golden paste, curcumin c3 complex 6g, boswellia 3,2, ginger powder, 10-15 ml of black seed oil, high Dha omega 3, krill oil and 10 ml of high caprylic mct oil . ¿what about Quercetin ?
- Dried parsley and celery juice for apigenin, around 50 gr of broccoli sprouts+mustard & (1-2 capsules) of mcs formulas broccoli (waiting to arrive)
- Honokiol for a time at least 1-2 gr divided in two dosages, at night i´d like to add mcs skullcap (how much would you use ?)
- Liposomal Vitamin c + ascorbic acid during the day, as much as i can. i do a tea from cordyceps and reishi extracts. As soon as i can i´ll add mcs maitake . ¿do you think coriolus is better of reishi for improve lymphocytes?
- Minerals: 50 mg zinc gluconate, magnesium, boron,chromium, yeast bound selenium 400 mcg, iodoral 12,5, trace minerals
- Red korean ginseng , jiaogulan and schizandra for adrenal health
- Milk thistle
-Drugs: Rotation of mebendazole, niclosamide and fenbendazole .Metformin 500 mg x 2, ldn, low dose aspirin 100 mg. i would like know if you think a statin is a good idea , or a fermentation inhibitor as i have been used this last months as Canagliflozin or diclofenac .
- I´m use R lipoic acid, carnitine,taurine,coq10, pqq and what to ask you about if you like to take NAC and Nicotinamide riboside from Life extension.
-For glutaminolysis i continue taking matcha tea,250 resveratrol, egcg 2 gr and ursolic acid
Rotation per weeks of andrographis , chaparral, pau de arco, cat´s claw, anamu, olive leaf, oregano oil, licorice root, colloidal silver.
I´m sorry for the long post
I wish you a quiet weekend at least 🙂
Sincerely,
Inaki
Dear Inaki,
Thank you for letting us know about such a great news! Clean PET-CT sounds perfect!!!
Are you doing the intravenous Vitamin C at home now?
Thank you so much with the support to MCS Formulas and for being one of our first customers! I very much appreciate that and I will do my best to help as much as I can.
Regarding Lymphocytes, Vitamin C that you are already using should help:
Influence of Vitamin C on Lymphocytes: An Overview https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874527/
The Effect of Vitamin C (Ascorbic Acid) in the Treatment of Patients with Cancer: A Systematic Review
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566697/Maitake beta-glucan promotes recovery of leukocytes and myeloid cell function in peripheral blood from paclitaxel hematotoxicity https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268513/
Maitake Beta-Glucan MD-fraction Enhances Bone Marrow Colony Formation and Reduces Doxorubicin Toxicity in Vitro https://pubmed.ncbi.nlm.nih.gov/14975363/?dopt=AbstractGelum Drops: reducing lactic acid, increasing hemoglobin and lymphocytes https://www.cancertreatmentsresearch.com/gelum-drops-reducing-lactic-acid-increasing-hemoglobin-and-lymphocytes-2/
Barely Grass is one of the best instead of multivitamins and for anemia https://www.hindawi.com/journals/omcl/2018/3232080/
Angelica sinensis, commonly known as dong quai or female ginseng, found as a supplement online
Acidic Polysaccharide from Angelica sinensis Reverses Anemia of Chronic Disease Involving the Suppression of Inflammatory Hepcidin and NF-κB Activation https://www.hindawi.com/journals/omcl/2017/7601592/
Experimental study of Angelica sinensis polysaccharide-iron complex on rats with iron deficiency anemia http://europepmc.org/article/CBA/639443Angelica sinensis, the most important herb in Dang-Gui-Bu-Xue decoction, could increase the quantity of red blood cells (RBCs), white blood cells (WBCs) and bone marrow nucleated cells (BMNCs), promote the proliferation of BMNCs and increase the quantity of multilineage progenitor cells (CFU-Mix) in a mouse model [10]. Previous studies have also shown that Angelica sinensis polysaccharide (ASP) can protect the hematopoietic function of CD34+ cells against adriblastin [11], improve the hematopoietic function of CD34+ hematopoietic stem/progenitor cells (HSPCs) by mitigating oxidative damage to stromal cells [12], and protect against X-ray irradiation-induced aging by inhibiting oxidative stress damage [13]. In addition, ASP promotes hematopoiesis and thrombopoiesis through the PI3K/AKT pathway [14]. We also confirmed the effect of ASP on mitochondrial membrane stabilization in another AA model by evaluating the number of mitochondrial, and concentration time curves of COX and MDH [15]. However, the anti-apoptotic function of ASP remains unknown. https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-020-02995-4
I would not go for mistletoe in your case, because that can trigger inflammation and that is not what you need specifically at this point, in my view.
Instead, I would focus on anti-inflammatory drugs and supplements.
Because of the reasons above I would indeed, consider adding Maitake.
Instead of multivitamin, I would use Barely Grass and try to take them from diet.
Great to hear that you are now on T3 instead of T4!
I am very happy for you Inaki! Take care of you!
Kind regards,
Daniel
Hi @daniel,
Thank you for your suggestions, i'm going to add many of them to try to up Hb and avoid for the moment to use the mistletoe as you mention the inflammation issue ... 🙂
I´d like to share with you what i´m taking because i´d like still todo a extensive protocol as my lymphoma has been tough and rebellious during these last ten years. So, I would consider still do a powerful approach in this NED status:
I daily take :
- First thing in the morning, rectal insufflation ozone
-Inflammation: Olive leaf, Golden paste, curcumin c3 complex 6g, boswellia 3,2, ginger powder, 10-15 ml of black seed oil, high Dha omega 3, krill oil and 10 ml of high caprylic mct oil . ¿what about Quercetin ?
- Dried parsley and celery juice for apigenin, around 50 gr of broccoli sprouts+mustard & (1-2 capsules) of mcs formulas broccoli (waiting to arrive)
- Honokiol for a time at least 1-2 gr divided in two dosages, at night i´d like to add mcs skullcap (how much would you use ?)
- Liposomal Vitamin c + ascorbic acid during the day, as much as i can. i do a tea from cordyceps and reishi extracts. As soon as i can i´ll add mcs maitake . ¿do you think coriolus is better of reishi for improve lymphocytes?
- Minerals: 50 mg zinc gluconate, magnesium, boron,chromium, yeast bound selenium 400 mcg, iodoral 12,5, trace minerals
- Red korean ginseng , jiaogulan and schizandra for adrenal health
- Milk thistle
-Drugs: Rotation of mebendazole, niclosamide and fenbendazole .Metformin 500 mg x 2, ldn, low dose aspirin 100 mg. i would like know if you think a statin is a good idea , or a fermentation inhibitor as i have been used this last months as Canagliflozin or diclofenac .
- I´m use R lipoic acid, carnitine,taurine,coq10, pqq and what to ask you about if you like to take NAC and Nicotinamide riboside from Life extension.
-For glutaminolysis i continue taking matcha tea,250 resveratrol, egcg 2 gr and ursolic acid
Rotation per weeks of andrographis , chaparral, pau de arco, cat´s claw, anamu, olive leaf, oregano oil, licorice root, colloidal silver.
I´m sorry for the long post
I wish you a quiet weekend at least 🙂
Sincerely,
Inaki
HI Inaki,
This is very extensive!
I will answer your questions:
- Quercetin is one that I would indeed use but maybe you already use many supplements ...
- Skullcap I would use about 2-3 g of extract
- I think Coriolus is better to support T cell activity while Reishi is better to support lymphocyte count.
- I like the idea of NAC in NED stage because of it's impact on micro-environment - I actually plan to write a post sometime
- in the rotation of Niclosamide, Mebendazole, etc. I would also consider Ivermectin
Please let me know if this answers your question and if there are other unanswered questions.
Thank you very much for selecting https://www.mcsformulas.com/ for a part of your supplements.
Kind regards,
Daniel
