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Please help with new strategy , refractory Hodgkin lymphoma

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Inabari
(@inabari)
Joined: 4 years ago
Posts: 46
Topic starter  

Hi everyone, 

My name is Inaki Barinaga, I'm 34 and from Spain. In 2006 I was diagnosed with a Hodgkin lymphoma 2b, did abvd chemo and got remision for 8 months

After relapsed I tried to cure the lymphoma with some diets and some supplements but at that time I have no much info and finally the lymphoma progressed a lot a I had to come back to the hospital. 

 

There I had mine and eshap chemo, some brentuximab. The disease shrunk but it was there, despite this they did me an autologous steam transplant. I was quite clean but not total. I did keytruda trial and after not big results they purpose me allo transplant.

 

But at this point, I decided to try ozone, hoxsey protocol, different suplements as curcumin, liposomal c, infrared sauna, cannabis... And after 6 months everything was fine, only a small focus in my armpit.

 

I think keytruda needs time and combining with these protocols I have success but since then I have been able to control the disease but since this spring I have more grow, anemia, and itching. 

I had and appointment with my hematologist, he was worried and until pet scan he gave a a round of cyclophosphamide with steroids and see what they see in the pet scan.

 

So I suppose they want to give chemo again as cyclophosphamide or bendustamine with brexuntimab to try the reduce or eliminate the disease. After they possibly suggest allo if i am clean or nivolumab as maintenance.

So, meantime I'm taking dca and learning in this blog how to maximize. I take b1, caffeine , omeprazol, tomorrow I'll speak with escozul,... Do you think could help with Hodgkin lymphoma? When I achieve 20 mg I feel as pain in the swelling lymp nodes, I felt more swelling after taking it and don't know if it's good sign or not...

I have contacted with care oncology center to try to starve my lymphoma, or try to maximize the chemo treatments or whatever can help me in my situation. 

Would you help to maximize my possible next chemo treatments? Would you incorporate dca with escozul, honokiol, between treatments and inmunoteraphy?

A lot of info that there is in this awesome blog, 3bp,2 dg, drugs. Combinations,.. Is very overwhelming at this moment and not easy to choose without mixing wrong things.

 

I'm sorry for this long thread, hope this could be a start to take correct decisions in my next weeks.

Looking forward to hearing from you soon 

Inaki 


   
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marcosbomber901
(@marcosbomber901)
Joined: 6 years ago
Posts: 93
 

Hi Iñaki.

I am spanish as you and reader of this incredible blog.I can put you in touch with the doctor who leads the treatment of my wife,based on the exposed systems in this blog. Contact me by private.


   
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marcosbomber901
(@marcosbomber901)
Joined: 6 years ago
Posts: 93
 

Iñaki excuse me

Can you give me your  facebook .Can you not contact for private


   
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Inabari
(@inabari)
Joined: 4 years ago
Posts: 46
Topic starter  

Hi Marcos!

 

Thanks a lot for reply my thread. I'm Facebook my name is Iña Bari and my email is [email protected]

 

Do you know why I can get private messages?

Warm regards 


   
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Daniel
(@daniel)
Admin
Joined: 7 years ago
Posts: 1156
 

Dear Inabari

First, here is a summary on how the conventional approach to treat and the related options: Management of Relapsed and Refractory Hodgkin Lymphoma in 2018 https://jamanetwork.com/journals/jamaoncology/article-abstract/2687374

I will include the paper as attachment here, in case you do not have access to it.

I understand you already tried checkpoint inhibitors which are some of the last line, and u are now going to Cyclophosphamide or Bendamustine (Treanda) with Brentuximab (Adcetris). Both Cyclophosphamide and Bendamustine are alkylating agents, so they should work well with 2DG metronomic (2DG-M), in the sense that 2DG-M is expected to enable or increase the effectiveness of this type of conventional therapies.

Due to the relevance of CCR5 in hodgkin Lymphoma (Ref.) Maraviroc may help https://www.cancertreatmentsresearch.com/an-anti-hiv-drug-reactivates-the-immune-system-to-against-cancer/

Your report regarding the use of DCA and the swelling that occurs following that it’s essential in my view. I checked what is the metabolic profile of hodgkin Lymphoma and here is a very good article giving an important message https://onlinelibrary.wiley.com/doi/full/10.1002/ijc.29934 The relevant message is found directly in the title: “Hodgkin and Reed–Sternberg cells of classical Hodgkin lymphoma are highly dependent on oxidative phosphorylation”.

Based on this, if I would be you I would immediately stop DCA and never touch that again. That is because Hodgkin lymphoma cells are highly dependent on a well-functioning mitochondria, and that is exactly what DCA helps. So in other words, there is a good chance for DCA to support Hodgkin lymphoma growth.

As the article above suggest, reducing mitochondria function in Hodgkin lymphoma cells may be the right treatment strategy. Here is a list of mitochondria inhibitors that could be accessible for most of the patients https://www.cancertreatmentsresearch.com/a-list-of-mitochondria-inhibitors/ Of this, Metformin is one of the most accessible, as well as Doxycicline. I would probably even add two mitochondria inhibitors at the same time as a part of a more comprehensive treatment protocol.

Therefore, in my view, combining the chemo that the oncologist is proposing with 2DG metronomic and with at least two mitochondria inhibitors, may be a good approach.

Using Tranilast and other NSAID medication (such as Aspirin) may help reduce fibroblast that are feeding tumor cells with lactic acid, for respiration.

Because hodgkin Lymphoma is relying so much on respiration, there is a good chance that MCT1 are very upregulated, which means that they may be highly sensitive to 3BP https://www.cancertreatmentsresearch.com/3-bromopyruvate/. However, when using 3BP there is a high chance of TLS that can be even lethal and it is specifically possible in blood cancers. Here I wrote a short post on managing TLS https://www.cancertreatmentsresearch.com/tls/ but the best way to address this to always increase the dose of treatments step by step whne we know that there is a risk of TLS.

I hope this helps and if you have questions please let me know.

Kind regards,
Daniel


   
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Inabari
(@inabari)
Joined: 4 years ago
Posts: 46
Topic starter  

Good night Daniel, 

 

First is need to express how I appreciate your comments. While I explore the possibility to add 2 dg drug in my protocol and two mitochondria inhibitors, could I ask you about some supplements that I'm thinking to start as are easy...

And very thanks to give me the if dca because I was insisting with the dosages and what I can do is fuel this when the disease is very active now... Thank you!! 

1-i have bought several bottles of. Honokiol, after reading positive things to assist killing steam cells during chemo. Do you think it would be possible to to 3g daily the days of chemo and between them?

2-i have also bought maitake D fraction, coriolus mushroom to assist my inmune system at this time

 

3-would you add in my case high omega 3 dosage? Including the chemo days?I suppose to take tumeric golden paste a lot green tea between chemo is a good strategy too 

4-as hl typical simptom I suffer a heavy itching episodes. Does this mean that some antihistamine drugs could halt this and attack hl too?

Warm regards! 

Inaki 

This post was modified 2 years ago by Daniel

   
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Daniel
(@daniel)
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Dear Inaki,

You are very welcome.

1. I like Honokiol and I think it can be used specifically in combo with Omega 3 - I see no reason why should not be used in combo with chemo but when I have the time I will check more details on this

2. Coriolus is one of my prefered mushrooms for immune system

3. Omega 3 in about 3-5g/day maybe should be good. Curcumine also. 

4. Cimetidine seems to be a very good solution for u https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1600342/?page=1 and its good in general as anti-cancer but always check interaction with other drugs here  https://reference.medscape.com/drug-interactionchecker?src=google

Kind regards,
Daniel


   
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Inabari
(@inabari)
Joined: 4 years ago
Posts: 46
Topic starter  

Thanks for your fast reply and clarifications. 

 

Have a very good night. 

 

A big hug 


   
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Inabari
(@inabari)
Joined: 4 years ago
Posts: 46
Topic starter  

Hi Daniel,

 
I'd like to update my status and treatments after pet scan and first chemo 
 
The pet scan was a little awful, I had all my right part of chest full of lymphoma, armpit, collarbone and less in my left part of chest. 
 
The selected chemo. Is brentuximab + bendastumime and corticoids. I did a two day fast before chemo and both days and after a couple of days I went to E.R because I was no able to breath.
 
After some tests they saw that my right lung was filled up of fluid and there was too in the heart. So they stated draining and it and I'm in the hospital to fix this problem, they are happy because it's because the large masses are dying, and this is the side effects. 
 
My idea is continuing to doing the fast every cicle of chemo to improve the effectiveness and help to my body. When I returned home I'm taking again metformin, atorvastatin, mebendazole and flarin.
 
Following your post ideas I'd appreciate your opinion about these questions.
 
1-as mitochondria inhibitors I'm taking honokiol, metformin,... Would you add doxycycline? Coc suggested me mebendazole and rotate with doxy but I wonder if it'd be a good idea to add this inhibitor too if it's compatible with my current chemo. If you think that I can add another different drug, please let me know 
 
2- as the chemo is alkaline base... Would be a good idea to take more than 20 mg of omeprazol? I suppose that it's good idea to try to alkalinize my body to increase the effectiveness of the chemo.
 
3-i have livon liposomal c at home, how many grams would you take between chemos to put more pressure to the lymphoma? In the morning I do ozone rectally, in the afternoon I can rotate liposomal c, or high dosage of oral curcumin.(I drink green tea during all day) 
 
4-do you think LDN can help with Hl? I read that possibly yes, but maybe it's not worth to add more and more things... I wonder the same thinking to add melatonin, as I'm not sure if it's a good addition in my case.
 
5- reading about hl I found that blocking autophagy could be a good idea too, do you think to take for example 5mg of desloratadine can be beneficial? 
 
For the moment I'm going to wait before considering 2dg or 3 BP because it's hard to get it from Spain.
 
Warm regards and thanks for the your help and time. Inaki 
This post was modified 2 years ago by Daniel

   
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Daniel
(@daniel)
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Hi Inaki,

Thank you for the update. Answering your questions:

1. It could make sense to introduce Doxy as suggested by COC specifically when dealing lymphoma - just make sure you introduce probiotics too

2. Taking a higher dose of Omeprazole, or even better Lansoprazole (also a PPI) would make sense when combining with chemo that is weak base

3. I do not have a strong opinion on liposomal Vit C. Maybe this website can answer your question  http://qualityliposomalc.com/index.html

4. Yes, I would add LDN

5. Chloroquine or Tetrandrine for autophagy 

Other remarks:

1. If would be me, I would not wait with implementation of metronomic 2DG after chemo - it should not be difficult to access when location is Spain

2. 3 days before chemo, I would stop all the treatments that slow down cancer cells (including Metformin etc.) for best chemo effectivness

Kind regards,

Daniel

 


   
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Inabari
(@inabari)
Joined: 4 years ago
Posts: 46
Topic starter  

Good night Daniel, 

 

Thank you for your suggestions. When you say that it could be bought 2dg, are you thinking to buy it from  http://www.sigmaaldrich.com/catalog/product/sigma/d8375?lang=en&region=NL or can I find from another source?

I'd take orally, I weight around 55-56 kg since I take coc protocol, I think metformin and atorvastatin don't help too much to gain kgs,... Is correct if I calculate that I'd need around 14 gr per month if I take 1 gr another each week?

When you suggest to stop metformin three days before chemo, do you include honokiol and doxy too? I'm not sure which products that I take in coc protocol plus honokiol could produce this...

The last question, is a good idea to take the morning before chemo the lansoprazole (what dosage?) and paracetamol for example?

 

A big hug 

 

Inaki 

This post was modified 2 years ago by Daniel

   
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Daniel
(@daniel)
Admin
Joined: 7 years ago
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Dear Inaki,

On 2DG: I was referring to using 2DG metronomic in intravenous form - this is available at a compounding pharmacy in Germany and there are clinics in Europe using it. I think Marcos can help you with pointing you towards the right direction as I saw he did with other Spanish speaking people. But I can also put you in contact with Spanish patients living in Germany and convincing their oncologists to help them with adding 2DG after chemo.

Yes, a few days before chemo I would stop all drugs that can slow down chemo, including Doxy.

Regarding Lansoprazole, yes, in my view it would be a good idea to take is prior to chemo. Same with Paracetamol. The Lanzoprasole dose would be the maximum dose as defined on the drug indication list. 

Beyond the above, drinking coffee before chemo should help to increase chemo access into the tumor. Niacin is also an option - a supplement - that would help chemo penetrate the tumor better - people taking it have to be carefully as at a too high dose it may cause  some side effects (flushes).

Kind regards,
Daniel

 


   
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Inabari
(@inabari)
Joined: 4 years ago
Posts: 46
Topic starter  

Hello Daniel,

I want to thank you for the help you gave me a few months ago. After 6 months of Brenxutimab-Vedotin I have obtained a pet with a complete metabolic response.

What I have been doing has been:

Fasting the days of chemotherapy, lonsaprazole, took acetaminophen and omega 3 to reduce glutathione, rectal ozone and baking soda to raise the ph from a couple of days before.
.
In turn, my protocol was more or less:

-Metformin 500 x 2
Berberine 500 x 3 + ceylan cinnamon
-Cencetina 500 x 6
-life extension bio curcumin 2 x 3
-thorne green tea extract 250 x 3 + green tea cups
-honokiol 3 gr daily
- Real herbs propolis 2 caps daily
-for gluthamine ursolic acid + life extension resveratol plus the egcc and curcumin
-mebendazole 2 x 100
-Doxy one month with 15 gr of liposomal livon c and another month rest doxy
-cholorquine 200 x 1 for autophogy
-flarin 400 mg x 3 daily
-Sodium selenite 200 microgrms
-zinc picolinate 50 mg
-enzymes as serraptsase and papain / bromelain
-Atorvastin 80 mg at night
-1 real herbs bitter melon extract
- cod live oil 9 caps daily
-coffee enemeas
- thorne b complex 1 cap
- 2 cayenne pepper caps, ginger caps
- ionic magnesium
- i rotate thorne arcetin 3 caps
-40 - 50 apricot kernels daily
-cannabis oil just to sleep
-vitamin k2 + micellized vitamin d
- niclosamide 2 g daily with breaks

My medical team want to haplo transplant to consolidate the remsion and they think possibly i'd cure definitvately but as you know haplo transplant can be very problematic with possible acute and chronic GVHD

. I'm thinking to skip it, because i think i could do a good protocol to mantain the cr, do you think it could be possible or is it better to try the haplo?

i'd know if you can help me select the best drugs / supplements / therapies that i could use if i don't choose haplo transplant:

-Currently i have changed the following: Instead of 1200 mg of flarin i take 400 in the morning and a baby aspirin before sleeping. Do you think is a good idea or is it better to take full flarin dosage or only a baby aspirin ...

-I have stopped honokiol since the pet scan to do a break. Would be a good idea to restart it?

-i plan to follow taking berbine and metformin, because without them my blood sugar goes around 100 and i think it should be lower than 100. Is ok to keep metformin and drinkine?

- As i started 400 mg x 2 of cimetidine to help my damaged immune system. One time in the middle of the night and in the middle of the afternoon. this one i take with 100 mg of mebendazole, cod liver oil to help. Do you agree to use cimetidine? How long can i use it?

-Real herbs propolis 2 caps. Do you have a favorite brand?

-Atorvastatin for now i'm alternating 40-80 mg

-i follow taking curcumin, resveratrol, ursolic acid, green tea extract, ginger, cayenne and quercetin. I suppose there is no problem to take them regularly-.

- To target cancer steam cells ... Could i continue rotating doxy with liposomal c? or is better another strategy?

- I take the apricot kernels as before

-Not sure what do to about chloroquine and honokiol. Maybe a rest?

-I have got persantin finally, but not sure if i should add it to attack the ebv ...

I'm sorry for the long post, could you give me your opionion of haplo transplant vs another options as following to do all this to avoid reccurrence? It scares me so much ..

thanks a lot for your opinions. Always helpful!

 

warm regards

This post was modified 2 years ago by Daniel

   
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Daniel
(@daniel)
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Hi Inabari,

It’s so nice to hear from you and to know that you are doing very well!

Answering your questions:

1. I cannot give any advice on the transplant – this has to be 100% your decision without any influence from my side
2. As prevention I think 400 flarin and a baby aspirin in the evening it’s enough
3. It’s good to do brakes from time to time but for now I would continue Honokiol
4. I would clearly keep Metformin and Berberine for longer term – some doctors are taking Metformin as a cancer preventive drug
5. People use Cimetidin for years without side effects as long as they do not introduce drugs that may interact with Cimetidine – due to it’s anti-metastasis activity, I would keep it for longer time
6. I like Propolis from Manuka but is a little expensive Propolis Bio 30 or bio100 – I actually like it a lot and would like to write a post on it one day
7. I would chance Atorvastatin with Pitavastatin if possible (morning and evening at 12hours). It’s expected to be more effective.
8. Curcumin, Resveratrol, EGCG and the others are all good in my view
9. I would not rotate Doxy with Vit C (if I understood correctly) but use them at the same time – although I do not like Doxy as an antibiatic, I think it has great potential in Lymphoma and I would keep it for a while
10. I not find very useful apricot kernels but if you like them it’s good idea to keep
11. Dipyridamole (persantin) is a good one at least because it helps the activity of the statins, but there is more behind that
In my view, what you are using above it’s already very good. Adding e.g. Silver Solution and Probiotics could help.
The only thing that I do not like and we need to think what has to be done is the high glucose level in the blood. That is something you need to be careful with because it will lead to a higher level of insulin in the blood and that helps tumors grow. So making sure you use a diet that lowers the glucose in the blood and/or increases insulin sensitivity could be very helpful. One more intensive option to address that could be to do for some time Restricted Ketogenic Diet. Another intensive option could be metronomic 2DG. Here are a few more drugs that can help along that line https://www.cancertreatmentsresearch.com/addressing-gluconeogenesis/

I hope this helps.

Kind regards,
Daniel


   
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Inabari
(@inabari)
Joined: 4 years ago
Posts: 46
Topic starter  

Good evening Daniel,

Thank you very much for your opinion on all these matters. The truth is that it is a very personal decision, but I am more inclined to be conservative and I would like to try it despite the risk of relapse (which also exists after making a haplo).

If possible, I would like to comment on the following points:

1- When you talk about atorvastatin and pitavastatin, it would be for example at night to take 40 mg of atorvastatin at 24h and at 12 noon, for example 2 mg of pitavastatin? I have understood that the most interesting thing would be to combine both, is that correct?

2- Respect to the "glucose issue". I wonder first if metformin 500 x 2 is a good dosage or could be benificial to try 500 x 3. I have reading your post of hydrazine sulphate. i found that it's a great drug / supplement, including especially possitive impact on hodgkin lymphoma.
What concerns me that you should avoid many things as:

ethanol
alcoholic beverages
barbiturates and tranquilizers (e.g. Thorazine, Compazine, Xanax, Valium, Dalmane, Ativan, Restoril, Halcion, Nembutal and Seconal, to name but a few)
sedatives in doses greater than 100 mg per day, especially benzodiazepines and phenothiazines
antihistamines
antiemetics
other agents that depress the central nervous system, such as morphine
foods with tyramine
Vitamin B6
Vitamin C in daily doses above 250 mg (from all sources)

Do you think it deserves to take it? I take many foods / supplements that contain this type of things. So i wonder if i could try 2dg and combine with my current metformin dosage or should too much. I am also more interesting if i could do orally as i'm in remission now, and what dosage could be safe and helpful.

I have ordered a glucometer to know my different sugar peaks, and after that I will make changes in diet towards keto or add 2dg / hydrazine sulphate. As i'm improving in my energy leves i plan to start with more exercise that i'm sure that it's going to help with the insulin issue.

3- I'm currently taking 200 mg of chloroquine daily + blueberries + zinc. My question is if it could be taken 200 x 2, and if you want to find hydroxychloroquine because of fewer side effects in the long term. As i plan to do several fast of 16 h during the weeks, i like to block autophagy wih it and help to manage the glucose while fasting.

4- is enough to 100 mg daily dosage of persantin? Should I be stopped for a while after some time?

5- I learned that you could be a good addition, so i'm taking 2 tablespoon of fresh parsley daily, Do you finde useful? i found a dried watercress that contains PEITC, what is your opinion about it? Could help to mantains at bay the lymphoma? I also take broccoli sprouts to add the sulforaphane that i understand that it's a good addition.

6. do you think that mebendazole is better to continue? I also find that Ivermectin could be a good drug, maybe rotate them?

7- I saw your last post in the lymphoma forum about the antibiotics. as you know i take doxy since i started with coc, but do you find more useful to take Clarithromycin or rotate both?

8-Can i ask you about your favorite probiotics? I take sauerkraut, miso, sometimes kefir or kimchi. could i add a specific probiotic supplement that could be more interesting than fermented foods?

I do not know how to thank you for everything you do, i'll donate money to support at least your costs to mantain the blog 🙂

best wishes

Inaki


   
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Inabari
(@inabari)
Joined: 4 years ago
Posts: 46
Topic starter  

Hi Daniels,

About the statin comment, i understood bad when i wrote the reply. How much of pivastatin is recommended if i take two times? 2 mg?

Thank you


   
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Daniel
(@daniel)
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@inabari

Hi Inabari,

I hope this answers your question https://www.cancertreatmentsresearch.com/cholesterol-lowering-statin-drugs-to-fight-cancer/#comment-8709

(I know you already saw the post but I add here the link to the post on Statins for those who will only read this discussion)

Kind regards,
Daniel


   
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Inabari
(@inabari)
Joined: 4 years ago
Posts: 46
Topic starter  

@daniel

Good afternoon,

I wish you are fine and enyoying some days if you are on holydays 🙂 .

After reading your last statin post i have changed how to take it, now i take 40mg at 12 am and the another one 12 pm. As i have several atorvastatin boxes i´m going to take them first and then start with pitavastatin .

Do you think can i take 80 mg for a long time without breaks (i´m on them since last november)? I know there are many people taking it long time but just thinking to stop some weeks and add coq10 in the future.

If it´s possible i´d like to ask you about dipyridamole dosage, would be enough to take 100 mg or could be better to work up to 200 mg daily.

As you suggested i´m going to add Colloidal Silver when i finish my current doxy protocol, do you think that is better to rotate both or take them simultaneously.

Since EBV is very involved in HL i know dypyramole can assist this but i have found that oleoupurin also fight it, Do you like olive leaf extract as Olive leaf extract - Maximum Strength - Oleuropein 50% - Hydroxytyrosol 20% - 120 Capsules.

I added dried watercress capsules and fresh parsley (1-2 tablespoon) after reading some good comments over the blog. if you know another positive addition to  my regimen, please let me know

Warm regards Daniel,

Once again, I don't know how to thank you for all the information you provide

 

Inaki


   
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Daniel
(@daniel)
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@inabari

Dear Inaki,

You are very welcome.

Taking a drug holiday from Atorvastatin (of about a month) is not required but could make very much sense https://www.statinanswers.com/holiday.htm

During such a holiday I would add HCA supplement discussed here https://www.cancertreatmentsresearch.com/reduce-cholesterol-in-cancer-cells-to-fight-cancer/

Dipyridamole is taken at 200mg 2 x day.  But we can always start with a lower dose, of 100mg/day.

Oleuropein from olive leaf extract is great anti inflammatory supplement. 

Kind regards,
Daniel


   
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Inabari
(@inabari)
Joined: 4 years ago
Posts: 46
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@daniel
Good night Daniel,
I´d like your opinion about taking chloroquine 200 x 2 daily, i have finally found hydroxychloroquine. So, what would you be your choice from both? i wonder if hydroxy is also a zinc ionophore, that it´s interesting thing too. I take around 50 mg of zinc gluconate daily, do you think that is a good daily dosage ? In the zinc thread i read that is used much more, but as it´s not my basic approach i doubt to take more than 50 mg

I have several bottles of life extension ultra soy supplement since a long time. Would be benificial to take genestain for a lymphoma? If so, do you know a possible daily dosage?

As my girlfriend is a nurse i´m thinking to do iv c at home in september, i wonder if you know where can i find vitamin c vials as i don´t have any contact for that in Spain.

I'm sorry to steal you a few minutes of your time, honestly
warm regards

Inaki


   
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Daniel
(@daniel)
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@inabari

Hi Inaki,

No problem. I do my best to answer as I find time. While I expect Hydroxychloroquine will be an ionophor as well due to chem structure similar to that of Chloroquine, I would need to study more this point to be 100% that is the case. I did a quick search in literature but there is nothing that comes up fast to answer the question. Please remind me again in a few weeks and I will try to go deeper in this subject.

Genistein is one of my preferred plant extracts. Daily dose can go from a few hundred mg/day up to much more as discussed here https://www.cancertreatmentsresearch.com/genistein-treatment-strategy-from-a-recent-patent/ I would anyway start with e.g. 200mg/day and go up step by step but it's difficult to get to a higher dose since most of the products on the market contain low amount of Genistein.

Vitamin C can be ordered from the compounding pharmacies mentioned here https://www.cancertreatmentsresearch.com/suppliers/  

For example, this compounding pharma in the Netherlands https://www.infinitypharma.com/ had it on prescription at about 20 euro for a 25g bottle for intravenous admin.

Kind regards,
Daniel


   
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Inabari
(@inabari)
Joined: 4 years ago
Posts: 46
Topic starter  

Good night Daniel,

First of all i´d like to wish you a merry christmas! I´m doing well but a little bit nervous because i´m having  a pet scan on 17 of january to confirm my remission again after finishing Brentuximab 2 weeks ago ....

I´d appreciate your thougs about these doubts:

Do you know if melatonin is a good supplement in cases of Hodgkin lymphoma or blood cancers ? I have found information that looks like a good addition but i read some comments from another affected guys that says that is good for all cancers but not in lymphoma. 

So my second question is if it´s a good supplement, would you suggest 20 mg daily or could be more helpful higher dosages? I have sleep problems since many years, and that affects to everything so i´m thinking if i could benefit from it sleeping better and  helping to my body if it helps when you have this type of disease .

My second question is if there is supplements , drugs or foods that can rise my nitric oxide because i have tested and i´m very low. I know that arginine supplements are not a good idea in lymphomas as could be a fuel for it, but low nitric oxide is not also good overally. Have you got any suggestions?

My last question is if my bloodworks shows lower protein than the minimum ... Would you eat more wild fish daily? I eat daily some of it in my lunch, i´m also trying to help my stomach acid was more acidific to improve absortion but i´m thinking to eat in the evening hemp seeds or something logical for a cancer patient ... Do you have any tips to rise proteins? I´m also considering to add some colostrum to see if it´s a gut problem, but very moderated because it´s all glutamine ...

A big hug from spain

Felices fiestas 🙂

Inaki

 

 

 


   
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Daniel
(@daniel)
Admin
Joined: 7 years ago
Posts: 1156
 

@inabari

Hi Inaki,

Nice to hear from you! Marry Christmas to you too!

I know the scans are not something to look forward too, I never liked them, but I think it is important that we find ways to put fear away. What I learned from dealing with cancer is to focus on today instead of tomorrow. To live and enjoy today and have positive expectations about tomorrow. You've seen it's possible to have remission and remember that if it comes back you will push it away again. And with all the celebrations during this time of the year, I hope it will be easy to focus on Today and enjoy.

Regarding your questions:

1. About Melatonin, I do not have any negative information - but if you have doubts and still want to take it, just take a lower dose, e.g. 5mg/day

2. For sleep, there are various options, including Honokiol, cortisol reducing supplements such as Aswaganda, Omega 3 in higher dose, Rhodiola Rosea, Vitamin C, and of course CBD/THC oil.

3. For protein, I would consider Organic Beef Bone Soup

I am think Johan will have nice additions on the above.

A big hug to you too and have a happy end of the year, and a great New Year with a lot of health and happiness!

Kind regards,
Daniel

 


   
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Sorin
(@sorin)
Joined: 5 years ago
Posts: 9
 

As stated in the documentation - Melatonin is not recommended for people suffering from:

  • autoimmune diseases
  • cancers (lymphogranulomatosis, leukemia, mieloma)
  • lymphoma;
  • diabetes 
  • epilepsy;

https://rum.alphahealthcaresystems.com/lekarstvo-melatonin-instrukcija


   
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Inabari
(@inabari)
Joined: 4 years ago
Posts: 46
Topic starter  

@sorin

Hi Sorin,

I have found contradictory info in both ways, as your not recommending in lymphomas and anothers that suggest is a good addition. Not easy no really be what to do https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.13966?fbclid=IwAR3t1YTKJfvuhwWs2s7ee123BNAlS38_aiGMG-Zfz9UMj8pgk4f4XA337S0

 


   
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Inabari
(@inabari)
Joined: 4 years ago
Posts: 46
Topic starter  

@daniel

Hi Daniel,

Do you think that bone broth supplements are a good choice? I´m really busy doing a lot another protocols as coffee enemas, ozone, excersise and have not a lot of free time. Would you choose bone broth above hydrolized collagen supplement? I´m a little lost which is a better addition for my case ...

i have very low nitric oxide in my body, i know that arginine is not a good idea with a lymphoma.Can you please give me your opinion if it is a good idea to take fermented korean ginseng, luteolin supplement or Salvia Miltiorrhiza for this purpose? Are better appoaches than taking these supplements? I have a lot problems to find a good salvia supplement or extract, if you have any ...

Finally, I have look for hydrogen water and water without deuterium because some info is running in cancer forums. Do you have a good consideration of them?

warm regards

 

Inaki


   
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johan
(@j)
Joined: 4 years ago
Posts: 1196
 
Posted by: @inabari

 

i have very low nitric oxide in my body, i know that arginine is not a good idea with a lymphoma.Can you please give me your opinion if it is a good idea to take fermented korean ginseng, luteolin supplement or Salvia Miltiorrhiza for this purpose? Are better appoaches than taking these supplements? I have a lot problems to find a good salvia supplement or extract, if you have any ...

 

Fisetin: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396042/

Iherb.com has chinese Salvia.


   
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johan
(@j)
Joined: 4 years ago
Posts: 1196
 
Posted by: @inabari

Good night Daniel,

First of all i´d like to wish you a merry christmas! I´m doing well but a little bit nervous because i´m having  a pet scan on 17 of january to confirm my remission again after finishing Brentuximab 2 weeks ago ....

I´d appreciate your thougs about these doubts:

Do you know if melatonin is a good supplement in cases of Hodgkin lymphoma or blood cancers ? I have found information that looks like a good addition but i read some comments from another affected guys that says that is good for all cancers but not in lymphoma. 

So my second question is if it´s a good supplement, would you suggest 20 mg daily or could be more helpful higher dosages? I have sleep problems since many years, and that affects to everything so i´m thinking if i could benefit from it sleeping better and  helping to my body if it helps when you have this type of disease .

My second question is if there is supplements , drugs or foods that can rise my nitric oxide because i have tested and i´m very low. I know that arginine supplements are not a good idea in lymphomas as could be a fuel for it, but low nitric oxide is not also good overally. Have you got any suggestions?

My last question is if my bloodworks shows lower protein than the minimum ... Would you eat more wild fish daily? I eat daily some of it in my lunch, i´m also trying to help my stomach acid was more acidific to improve absortion but i´m thinking to eat in the evening hemp seeds or something logical for a cancer patient ... Do you have any tips to rise proteins? I´m also considering to add some colostrum to see if it´s a gut problem, but very moderated because it´s all glutamine ...

A big hug from spain

Felices fiestas 🙂

Inaki

 

 

 

Hi Iñaki, do you eat beans? Some wild fish with black beans or pinto beans would provide plenty of protein.


   
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Inabari
(@inabari)
Joined: 4 years ago
Posts: 46
Topic starter  

@johan

@daniel

 

Dear Daniel and Johan

 

Thank you for your replies, i odered salvia a fisetin to add to my regimen. i have done the pet scan and bloodwork the last friday and i´m waiting for the results to confirm if i continue in NED.

 

I eat beans  chickpeas,... but i added a little bit creatinine, colostrum and collagen supplements to my daily intake and i feel much more stronger. I take them in small quantities because i don´t like the idea to take a lot of glutamine with a lymphoma, but i think my healthy cells are happy with the addition. Do you think it´s safe to take them routenely?

Can i ask you what do you think about continuing to take chloroquine to inhibit de autophagy when you are NED. I do intermitent fasting daily and i have no more chemo so i wonder if it´s a drug that helps in NED conditions.

Another question is if you think that it´s a good idea to the r alpha lipoic acid daily 

In other to mantain the inflammation low, do you miss any supplement with this target? i take daily:

Flarin drug

Curcumin c3 complex

Olive leaf extract

Quercetin

Omega 3

Ginger capsules

Would you add boswellia or another good suggestion?

I continue taking another things as honokinol, metformin, berberin, 40 mg atorvastatin, watercress, broccoli sprouts, mebendazole/niclosamide, andrographis, cinnamon, garlic, biopirerine, green tea extact, ashwagandha

warm regards,

I appreciate your thoughts 🙂

 

Inaki


   
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Daniel
(@daniel)
Admin
Joined: 7 years ago
Posts: 1156
 

@inabari

Hi Inaki,

Maybe Creatinine and Colagen I would only take from time to time. 
Those you use look good to me. Maybe will add low dose aspirin too?

Kind regards,
Daniel

 


   
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