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Mitochondria inhibitors help improve effectivness of conventional therapies in chronic myeloid leukemia (CML)

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Daniel
(@daniel)
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CML shows up on PET scan  https://www.ncbi.nlm.nih.gov/pubmed/17885356

This means that regarless of the genetic mutations, there is a good chance it will be sensitive to metabolic treatments such as 2DG.

However, next to glycolisis inhibitors, it may be a good idea to add mitochondrial inhibitors.

According to this PhD thesis, mito inhibitors will improve effectiveness of conventional therapies against CML cancer stem cells  http://theses.gla.ac.uk/8615/1/2017KuntzPhD.pdf

Here is a list of mitochondria inhibitors easily accessible  https://www.cancertreatmentsresearch.com/a-list-of-mitochondria-inhibitors/  one of which is Metformin.


   
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