The Nobel Prize in Physiology or Medicine was awarded for discovering use of Pseudouridine to suppress immune responses to synthetic mRNA, and use of that discovery in COVID-19 mRNA vaccines.
https://rwmalonemd.substack.com/p/pseudouridine-what-is-it-and-why
The Nobel Prize in Physiology or Medicine was awarded for discovering use of Pseudouridine to suppress immune responses to synthetic mRNA, and use of that discovery in COVID-19 mRNA vaccines.
https://rwmalonemd.substack.com/p/pseudouridine-what-is-it-and-why
more context: https://www.youtube.com/watch?v=PnJ5T1Enwq4
The Nobel Prize in Physiology or Medicine was awarded for discovering use of Pseudouridine to suppress immune responses to synthetic mRNA, and use of that discovery in COVID-19 mRNA vaccines.
https://rwmalonemd.substack.com/p/pseudouridine-what-is-it-and-why
more context: https://www.youtube.com/watch?v=PnJ5T1Enwq4
Around the 10-minute mark, Professor Angus Dalgleish, MD, FRCP, FRCPA, FRCPath, FMedSci says "The T-cells control this disease [cancer]".
The professor talks about the importance of Vitamin D, from his observations during his long career as an oncologist he noted that it is vital to have a Vitamin D level close to or above 100 nmol/L (which is 40 mg/mL).
Vitamin D Controls Tumor Growth and CD8+ T Cell Infiltration in Breast Cancer
https://www.frontiersin.org/articles/10.3389/fimmu.2019.01307/full
"We show that vitamin D decreases breast cancer tumor growth. Immunomonitoring of the different immune subsets in dissociated tumors revealed an increase in tumor infiltrating CD8+ T cells in the vitamin D-treated group. Interestingly, these CD8+ T cells exhibited a more active T cell (TEM/CM) phenotype. However, in high-fat diet conditions, we observed an opposite effect of vitamin D on breast cancer tumor growth, associated with a reduction of CD8+ T cell infiltration."
I've posted the following study before and it's worth posting again:
Microenvironmental Ammonia Enhances T cell Exhaustion in Colorectal Cancer
https://www.biorxiv.org/content/10.1101/2022.05.25.493422v1.full
"We demonstrate that enhancing ammonia clearance reactivates T cells, decreases tumor growth, and extends survival. Moreover, decreasing tumor-associated ammonia enhances anti-PD-L1 efficacy. Our findings indicate that ammonia detoxification can reactivate T cells, highlighting a new approach to enhance the efficacy of immunotherapies."
What Foods Can Increase T Cells?
https://www.marham.pk/healthblog/what-foods-can-increase-t-cells/
Professor Dalgleish also noted the importance of an anti-inflammatory diet.
one of the issues with m R N A vac. that has been observed is increased igg4, Professor Angus Dalgleish also briefly mentions it in the video. In this study, "High Expression of Galectin-3 in Patients with IgG4-Related Disease: A Proteomic Approach" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448067/ the researchers found that galectin-3 levels were 13-fold higher in IgG4-related pancreatitis. And we know high levels of galectin3 can produce heart failure and are also enhanced in cancer.
Inhibiting Galectin 3 might be a good strategy to address the issue with the higher levels of igg4.
Here are a few options to inhibit galectin-3: MCP, curcumin, spiraeoside (red onions), QiShenYiQi, formic acid (apples, strawberries, raspberries, honey, nettles).
@j Excellent advise, Johan!!!!! This professor's got it going on!!!!!!!!! A real research scientist/medical doctor who actually wants to cure his patients!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! Can we clone him?????????? Thanks for posting and for your additional helpful suggestions and reminders!!!!
Here are a few options to inhibit galectin-3: MCP, curcumin, spiraeoside (red onions), QiShenYiQi, formic acid (apples, strawberries, raspberries, honey, nettles).
Effects of Aspirin and Indomethacin on Galectin-3
https://core.ac.uk/reader/14374990
Here are a few options to inhibit galectin-3: MCP, curcumin, spiraeoside (red onions), QiShenYiQi, formic acid (apples, strawberries, raspberries, honey, nettles).
Effects of Aspirin and Indomethacin on Galectin-3
https://core.ac.uk/reader/14374990
Nigella sativa seed reduced galectin-3 level and liver fibrosis in thioacetamide-induced liver injury in rats
@j Taking plenty of my Nigella, hahahah!!! Question for you.... have you seen much on mustard seed? A little bird whispered that to me today. It's in the bible... so..... I mean I know it is related to cruciferous vegetables, but what about the little mustard seed itself. I see a few things....
@j Taking plenty of my Nigella, hahahah!!! Question for you.... have you seen much on mustard seed? A little bird whispered that to me today. It's in the bible... so..... I mean I know it is related to cruciferous vegetables, but what about the little mustard seed itself. I see a few things....
@rosed great! Good question, and in fact I haven't come across much about mustard seeds, not anything I can remember other than what you mention regarding their use with broccoli.
Talking about the bible, I was looking at cancer and disease in history and many diseases are mentioned in the bible but nothing that resembles cancer really.
I'm curious now, what are you seeing 😉
The Nobel Prize in Physiology or Medicine was awarded for discovering use of Pseudouridine to suppress immune responses to synthetic mRNA, and use of that discovery in COVID-19 mRNA vaccines.
https://rwmalonemd.substack.com/p/pseudouridine-what-is-it-and-why
more context: https://www.youtube.com/watch?v=PnJ5T1Enwq4
Around the 10-minute mark, Professor Angus Dalgleish, MD, FRCP, FRCPA, FRCPath, FMedSci says "The T-cells control this disease [cancer]".
The professor talks about the importance of Vitamin D, from his observations during his long career as an oncologist he noted that it is vital to have a Vitamin D level close to or above 100 nmol/L (which is 40 mg/mL).
Vitamin D Controls Tumor Growth and CD8+ T Cell Infiltration in Breast Cancer
https://www.frontiersin.org/articles/10.3389/fimmu.2019.01307/full
"We show that vitamin D decreases breast cancer tumor growth. Immunomonitoring of the different immune subsets in dissociated tumors revealed an increase in tumor infiltrating CD8+ T cells in the vitamin D-treated group. Interestingly, these CD8+ T cells exhibited a more active T cell (TEM/CM) phenotype. However, in high-fat diet conditions, we observed an opposite effect of vitamin D on breast cancer tumor growth, associated with a reduction of CD8+ T cell infiltration."
I've posted the following study before and it's worth posting again:
Microenvironmental Ammonia Enhances T cell Exhaustion in Colorectal Cancer
https://www.biorxiv.org/content/10.1101/2022.05.25.493422v1.full
"We demonstrate that enhancing ammonia clearance reactivates T cells, decreases tumor growth, and extends survival. Moreover, decreasing tumor-associated ammonia enhances anti-PD-L1 efficacy. Our findings indicate that ammonia detoxification can reactivate T cells, highlighting a new approach to enhance the efficacy of immunotherapies."
What Foods Can Increase T Cells?
https://www.marham.pk/healthblog/what-foods-can-increase-t-cells/
Professor Dalgleish also noted the importance of an anti-inflammatory diet.
Study finds hallmarks of T cell exhaustion within hours of tumor exposure
https://www.sciencedaily.com/releases/2023/08/230803112958.htm
