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Personalised Vaccine in a dog model


anthraxvermilion
(@anthraxvermilion)
Joined: 2 years ago
Posts: 1
Topic starter  

Greetings,

Here is a link to an Open Access paper:

https://www.mdpi.com/2306-7381/5/4/87

It describes how dogs with advanced cancer were treated by obtaining a small sample of the tumor and creating an individual vaccine for each dog. It was not successful in every case, of course, but it gives hope. I understand this will be translated to human trials at some stage.

It sounds so simple to do that I am sure it could even be a "DIY" project for some if time is short and they can get the starting material.

Apologies if this has been posted earlier.

Regards,

Anthrax


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dumbcritic
(@dumbcritic)
Joined: 4 years ago
Posts: 100
 

There are a number of trials https://clinicaltrials.gov/ct2/results?term=neoantigen+vaccine&Search=Apply&recrs=b&recrs=a&age_v=&gndr=&type=&rslt=

 

Early data from Gritstone Oncology shows its vaccine could end up being best-in-class (imo) [1]. Here are links to the trials they are running [2,3].

 

Refs:

1 https://www.fiercebiotech.com/biotech/gritstone-posts-one-most-potent-immunogenic-responses-for-a-neoantigen-vaccine

2 https://clinicaltrials.gov/ct2/show/NCT03639714

3 https://clinicaltrials.gov/ct2/show/NCT03953235


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