Dr. Williams Clinic  

  RSS

Meech
Eminent Member
Joined:8 months  ago
Posts: 20
01/09/2017 8:36 pm  

I just got back from Mexico city after having done treatment with Dr. Williams this past Monday. The treatment consisted of me being put under general anesthesia, followed by the cryoablation of one large tumour in the liver, along with the injection of three different types of immunotherapy drugs (PD-1, PD-L1, CTLA4 inhibitors).

The actual procedure lasted about two hours. Prior to this, I was hooked up to an IV, had bloodwork drawn twice and was able to speak with Dr. Williams at length about the procedure.

I woke up with minimal pain. My only pain was in my nephrostomy tube site; Dr. Williams assumed that it was because of the anesthetic and the relaxation of those muscles. I took 2mg hydromorphone and the pain ceased and never returned.

About a day after the procedure, I developed a fever of about 39.4 degrees celsius. Generally a low grade fever happens but mine happened to be a bit higher grade. The fever has now subsided to a low grade one (around 37 degrees),  three days after it began.

On top of the procedure, Dr. Williams recommends a list of supplements to increase the efficacy of treatment. Off the top of my head, these include:

Cyclophosphomide, aspirin/celebrex, januvia, Cialis, Pantoprazole, Propranolol, and a probiotic. All are taken at varying schedules (eg. cyclophosphomide is 50mg once every two days; januvia is taken 7 days on, 7 off; Cialis is daily for three months). He also recommended eating a lot of cashews.

 

I'm happy to answer any other questions people may have, and I hope to continue updating everyone as time goes on.

Edited: 2 months  ago

ReplyQuote
Daniel
Eminent Member Admin
Joined:2 years  ago
Posts: 41
01/09/2017 9:22 pm  

Great to hear from you Meech! What is the proposal of dr. Williams as next steps? Also what was the cost so far? Do you have any idea about the doses used for the immuno therapies? Thank you, and again, very nice to hear from you!


ReplyQuote
Meech
Eminent Member
Joined:8 months  ago
Posts: 20
01/09/2017 9:32 pm  

Good to be back, I've been a bit busy with all the treatment stuff so I haven't posted as much. The cost of treatment was about $55,000USD. Typically it's within the $50-60k USD range. Then on top of this, the stay at the hospital and use of their facilities (CT scan room, bloodwork, etc.) is about $2000-$5000 USD depending on your stay. My stay was $2200USD. I will say that the facilities are excellent. You get a very large private room with a TV, your hospital bed, and a pull-out couch type of thing for a visitor, as well as a private bathroom. Nurses come to check in on you quite frequently. From what I understood, this is a "private hospital", so not quite a clinic, and not a crowded state-run hospital.

 

I'm actually unsure of what the doses were but I may try to see if I could get the documentation of my treatment in the coming days.


ReplyQuote
Meech
Eminent Member
Joined:8 months  ago
Posts: 20
01/09/2017 9:37 pm  

Forgot to answer the next steps.

 

The next steps are basically to take the medicines and supplements as recommended and to do CT scans and bloodwork to monitor my condition. He said that the supplements increase the efficacy of the immunotherapy by about 30% so it seems pretty imperative to take it all. Prior to treatment, Dr. Williams' team sent me a dropbox link full of resources/academic journals explaining why these particular drugs help the immunotherapy be more effective.

 

Dr. Williams also mentioned that some cancers are much more challenging to induce a response with, although they aren't impossible. He said colorectal cancer would be one where there are more difficulties. And this can be seen through conventionally administered immunotherapy being a pretty big failure with CRC.


ReplyQuote
Daniel
Eminent Member Admin
Joined:2 years  ago
Posts: 41
01/09/2017 10:37 pm  

Thanks for the details Meech. Expensive indeed. Cryo + imuno could lead to a systemic response. I do not know Januvia and Cialis but all the others are known a enhance the immuno response via different mechanisms. I also added sometime ago some of the ideas on supporting the immune system when doing the immunotheraphies on the Dendritic Cell post and anti PD1 post, in case you may want to have a look at them. Best wishes!


ReplyQuote
Meech
Eminent Member
Joined:8 months  ago
Posts: 20
04/09/2017 8:31 pm  

Thanks Daniel, I'll check it out.


ReplyQuote
Emad
 Emad
Active Member
Joined:2 years  ago
Posts: 7
05/09/2017 12:17 am  

nice to hear from you meech , I strongly believe that things is going good

is this kind of treatments are done in cycles or its just done only once ? probably how much the treatment will remain killing cancer ?

also , did he targets all the big tumors around the body or just targeted the liver tumors ?

 

thank you so much , always wish the best


ReplyQuote
Meech
Eminent Member
Joined:8 months  ago
Posts: 20
07/09/2017 5:12 pm  
Posted by: Emad

nice to hear from you meech , I strongly believe that things is going good

is this kind of treatments are done in cycles or its just done only once ? probably how much the treatment will remain killing cancer ?

also , did he targets all the big tumors around the body or just targeted the liver tumors ?

 

thank you so much , always wish the best

Hi Emad,

ideally, the treatment is only done once. For me, he only targeted liver tumours and said that the liver microenvironment is such that inducing a systemic response is more likely when the liver is treated. For example, he said that more often, he tends to see lung tumours shrink if he does the liver, but less frequently will see liver tumours shrink if he treats the lung. It's important to note that the ablation is only a secondary treatment used to induce a better immune response. The immunotherapy is the main treatment.


ReplyQuote
Emad
 Emad
Active Member
Joined:2 years  ago
Posts: 7
09/09/2017 12:01 am  

This sounds very good Meech

Thank you , always love to hear good news from you


ReplyQuote
marcosbomber901
Active Member
Joined:6 months  ago
Posts: 7
04/10/2017 7:17 pm  

Hi Meech

Can you tell me the dosage of the medicines your doctor Jason Williams recommended after the immunotherapy.Januvia,propranolol,esomeprazole and aspirin/celecoxib.

thank you


ReplyQuote
  
Working

Please Login or Register