Blocking a pathway unleashes the anti-cancer immune response
Topic starter 16/03/2021 1:37 am
Blocking the SREBP pathway unleashed a potent antitumor response in mice with melanoma treated with immunotherapy called anti-PD-1.
SREBP inhibitors have been discussed here an includes Metformin https://www.cancertreatmentsresearch.com/?s=SREBP
This could explain why Metformin has been found to help with effectiveness of anti-PD-1 immunotherapy.