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Blocking a pathway unleashes the anti-cancer immune response

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(@daniel)
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https://www.sciencedaily.com/releases/2021/02/210224120316.htm

Blocking the SREBP pathway unleashed a potent antitumor response in mice with melanoma treated with immunotherapy called anti-PD-1. 

SREBP inhibitors have been discussed here an includes Metformin https://www.cancertreatmentsresearch.com/?s=SREBP

This could explain why Metformin has been found to help with effectiveness of anti-PD-1 immunotherapy.


   
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