Long-Term Survival of a Patient With Stage IV Renal Cell Carcinoma
The Long-Term Survival of a Patient With Stage IV Renal Cell Carcinoma Following an Integrative Treatment Approach Including the Intravenous α-Lipoic Acid/Low-Dose Naltrexone Protocol id/Low-Dose Naltrexone Protocol https://journals.sagepub.com/doi/10.1177/1534735417747984
"In this case report, we describe the treatment of a 64-year-old male patient diagnosed with metastatic renal cell carcinoma (RCC) in June of 2008. In spite of a left nephrectomy and the standard oncological protocols, the patient developed a solitary left lung metastasis that continued to grow. He was informed that given his diagnosis and poor response to conventional therapy, any further treatment would, at best, be palliative. The patient arrived at the Integrative Medical Center of New Mexico in August of 2010. He was in very poor health, weak, and cachectic. An integrative program—developed by one of the authors using intravenous (IV) α-lipoic acid, IV vitamin C, low-dose naltrexone, and hydroxycitrate, and a healthy life style program—was initiated. From August 2010 to August 2015, the patient’s RCC with left lung metastasis was followed closely using computed tomography and positron emission tomography/computed tomography imaging. His most recent positron emission tomography scan demonstrated no residual increased glucose uptake in his left lung. After only a few treatments of IV α-lipoic acid and IV vitamin C, his symptoms began to improve, and the patient regained his baseline weight. His energy and outlook improved, and he returned to work. The patient had stable disease with disappearance of the signs and symptoms of stage IV RCC, a full 9 years following diagnosis, with a gentle integrative program, which is essentially free of side effects. As of November 2017 the patient feels well and is working at his full-time job."
"The key therapeutic agents initially prescribed by BB were intravenous (IV) vitamin C 25 to 50 g every morning and IV racemic α-lipoic acid (ALA) 300 to 600 mg every afternoon after a meal (to prevent hypoglycemia). These therapies were administered at the clinic on an outpatient basis. The oral protocol included low-dose naltrexone (LDN) 4.5 mg at bedtime, the oral Triple Antioxidant Therapy protocol2,3 with (1) racemic ALA 300 mg twice daily, (2) selenomethionine 200 µg twice daily, and (3) silymarin 900 mg twice a day along with 3 professional-strength B-50 complex capsules a day. Oral hydroxycitrate (HCA) 500 mg 3 times daily was added to the protocol in September 2013, based on the work of Dr Laurent Schwartz et al.4,5
It was also suggested that the patient followed the IMCNM lifestyle program including a strict diet with 4 servings of fresh vegetables a day, very low simple carbohydrate intake, and no processed food, especially preserved animal products. Some organic animal protein was allowed. In addition, an exercise and a stress reducing program were prescribed.
This program had been used frequently at the IMCNM with many patients and was previously reported in the scientific literature in 4 cases of pancreatic cancer and one case of B cell lymphoma.3,6,7
After 1week of receiving IV ALA and IV vitamin C, he began to subjectively look and feel better. He reported “increased energy and a new sense of well-being.”
After this 1 week of initial treatment in the author’s clinic, the patient went home and adhered to the programmed lifestyle and supplements, and a local integrative doctor in Fort Worth, Texas, continued the IV ALA infusions twice a week and IV vitamin C twice a week."
"In a report of three cases, Berkson, et al. depicted that a LPA/low dose naltrexone protocol in people with metastatic and nonmetastatic pancreatic cancer resulted in [18F]-FDG PET scans without evidence of disease approximately 4 mo after treatment."
Berkson BM, Rubin DM, Berkson AJ. Revisiting the ALA/N (alpha-lipoic acid/low-dose naltrexone) protocol for people with metastatic and nonmetastatic pancreatic cancer: a report of 3 new cases. Integr Cancer Ther. 2009;8:416–22. doi: 10.1177/1534735409352082.