The site has hit 1Meg and we are still going strong! This is a substantial achievement especially in light of the fact that we have now seen unmistakable benefits in those who have pursued metabolic cancer approaches as suggested here.
Thank you everyone for adding to the knowledge base and helping the others who will need it when they too embark on their cancer journeys.
Hi J, thanks for your post. Actually I was thinking I should write a short post on this, anticipating that 1.000.000 visitors will be reached towards the end of the month. But there is now an explosion of visitors from Korea as Fenbendazole story just became viral there too. It's amazing to see in real time how a story becomes viral. Yes J, let's keep up and create more and more value for people in need! Like I said, it;s always a pleasure to see your never ending enthusiasm! Of course I see you take some brake from time to time to regain your energy 😀
Wow! congratulations on a job well done!
Dear @daniel,
We feel like we just begin to understand and reveal the valuable articles and information in your blog!
It is indeed a huge multiplier for our ability to reach the relevant information and drop the non-relevant one, as we feel like standing in front of an ocean of information with a bucket in our hand, trying to empty this ocean...
1,000,000 might seems as just some number but I hope that it will be another trigger to help us encourage doctors, oncologists and cancer treating community to look into and adopt non SOC low-risk therapies, as we all know the SOC is simply not enough and other strategies are currently ignored/ neglected by the main stream therapy providers.
Many many thanks for your efforts and help and best wishes and health to all!
Regards, Nissim
Since we speak about this milestone it also makes a lot of sense to speak about 3BP, the substance due to which I decided to start this website. Here is a new article on 3BP that you may like to read:
Diverse Stakeholders of Tumor Metabolism: An Appraisal of the Emerging Approach of Multifaceted Metabolic Targeting by 3-Bromopyruvate https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620530/
Thank you D. Yes, I saw that one a months ago when it was pre-pubmed. ? {I am not much of emojier, though I thought I should try it out.}
It is true that I have stepped back from the forum for the last while. It has felt so great to charge up those batteries again.Another aspect that I have been struggling with is: What is the next direction to take with the research? We have found so many potentially useful treatments, how can we create a rational treatment plan with our results? I have also thought that I should investigate the books written for the general cancer population. I have focused mostly on the recent research base in articles, though the wider view could also be helpful.
It is heartening when you have built something up to watch whether others will step into a gap or will merely step back from the challenge: sometimes in life when some people do all the rowing, others no longer know how to themselves. Yet, on this forum we have such a deep bench that when one member pulls back there is another wave of replacements. I will have to watch out for this youngster johan. If I am not careful, he could assume the j mantle. However, as I said it is such an honor that this is in fact true.
It is also encouraging that mainstream medicine is now offering patients treatments with increasing success. 5 year survival for metastatic melanoma at almost 40% is not great, though is a tremendous improvement from not the distant past.
https://www.nejm.org/doi/full/10.1056/NEJMoa1904059
I feel very much the same way, J. Certain strategies to tackle cancer seem so good it's hard to believe the lack of follow-through. Or at least that is how it seems. But it's exciting to see how this site is growing and receiving more visitors each day. I think this will eventually help bring about the focus we're looking for.
What has fascinated me from the beginning is the fact that with a metabolic approach to cancer the treatment becomes somewhat easier...not that scary for patients. And I'm glad that following this approach more people can be helped, people that don't have much money, and the metabolic approach doesn't equal BROKE for most people. Thank you for all your work
Yud, thank you for your interesting comments on forum. Yes, you are totally right about the metabolic approach.
I am not aware of anyone within the metabolic cancer framework who is an MD, but it is exactly what immediately attracts people who aren't MDs and want to figure things out for themselves. When you actually go to cancer textbooks they do not even mention metabolics. I am speechless! How can you talk about cancer without talking metabolics? It is very weird. If I had to post about the non-metabolic side of cancer I would be almost totally stumped. What is there to say? Almost everything flows through the metabolic pathways. It should be no real mystery to anyone that many high end scientists (Warburg ...) were intuitively attracted to cancer metabolics.
Oftentimes successful cancer drugs that are supposedly non-metabolic have as a primary or at least important mechanism of action metabolic biology. Sometimes even high tech medicinal chemistry with nM potency and very end science winds up being ultimately a tweaker of metabolism. One can hit a target very very specifically yet what happens then as it propagates through the network?
With your first point, again, exactly right. I do not think people often appreciate how profound the anti-cancer effects have been with metabolics, this is even more true because there are often so few side effects. The 3-BP liver patient with his first dose of 3-BP felt better almost right away on the first day and wanted to go out for dinner. This is very startling. He had had no appetite for months and was not in great condition. The next dosing round was almost fatal because of a massive massive TLS response. Yet, once again there were mild if any actual direct treatment toxicity. Same with the 3-BP melanoma patient: entire tumor mass shut down. Metabolics can produce large responses fairly often without side effects.
People have this idea that cancer treatment must hurt to work: no pain, no gain. For me the real logic is more like: if there is pain something is wrong. With Bracht, I would have immediately asked for NAC when things started to go wrong right from the start. Shutting down a tumor mass under proper control should create such side effects. This is a constantly recurring feature of metabolic treatment: vitamin C, sal, ... there can be substantial anti-cancer effects with few side effects which can increase risk for people unaware of this feature.
The big problem is that we do not have the solid protocols that exist for mainstream treatments. Doctors are not allowed typically to go off the drug list to help their patients. I think that it would be such a victory for medicine if this were more clearly defined. I am unsure whether those without the needed training should dispense medical suggestions; yet as we have seen at some point in the treatment cycle doctors simply have nothing left that they can offer and then they are almost compelled to release their patients even when this means that no treatment can be given.
johan, yes there are so many new people. It is so gratifying to see this. It feels like we have reached a critical mass where a self-sustaining process has been created. It can be difficult when the same builders need to keep on building forever and a liftoff is never reached.
However, there is so much value that has been accumulated here that people will tend to gravitate to it. One can even feel a network effect occurring in which isolated people all over the world who have a piece of the puzzle can be integrated into our collective effort. I would tend to agree with the idea that we are stronger together. There are different flavors of treatments (e.g. vitamin C) that can add a different variant if another protocol is not effective. One of my big aha moments was realizing that probably many of these apparently separate approaches at a fundamental level are likely quite similar in terms of pathway involved. There are only a few central pathways open to metabolics. One of the tasks that perhaps we should dedicate ourselves to is bringing together the treatments suggested on thread. For someone starting off with no clue, a list of nice and safe and mostly easily available treatments would be of great help. Some of these are readily available, though such people would need to have a certain skill level.
J, on the one hand, I like the idea of distilling all the various options into a sort of protocol. On the other hand, I feel we may just have to let it emerge organically. And help this process with useful pointers. Which I think is going on already here and probably on other sites on the internet.
Yud raises an important point. Modern medicine may have promising treatments in the pipeline, but at what cost? Albert A. Bartlett, in a presentation on arithmetics gave an example of the cost escalation of bladder surgery, which in 1950 cost USD360. By 1975 the same surgery already cost USD2200. So he noted that considering the inflation rate of the cost of the surgery (aprox 10% per year) "the lesson is awfully clear - if you're thinking about gall bladder surgery, do it now!"
I remember the time I first stumbled upon the idea of altering cancer metabolism, I was reading a blog :healing cancer naturally and all over the place there was this Budwig diet thing... I didn't know what to think I hadn't read her books but I saw people where using it to treat their pets cancer. So I told my brother who is a Vet and we started treating animals with only the cottage cheese and the flax seed oíl as well as meat, chicken and vegetables no artificial food and we were amazed by the results so I felt I had found something quite interesting... Time passed by and I had a patient with prostate cancer who had been given up by oncologists, I told him about the Budwig mix and asked him to remove all artificial food and sugars added, this was a bed ridden patient with metastases in his groin and bones with lots of pain and 4 months later he was riding his bike full of life, then he went to the oncologist and was advised to take Zometa for a small dot in one of his knees on the bone gammagram and he died after a few doses everyone said he died of cancer I started treating other people but soon I realized that the only chance of helping someone was if I saw them before they started any chemo... Of the few that have survived they later develop side effects from chemo/cytotoxic/cytostatic medication... I'm glad to learn about so many more options to help my patients
Yud, that's an awesome comment! Thank you for posting! You have a very interesting perspective that I ( and likely many others on forum) would like to hear more of. Have you mostly treated with Budwig or have you also included other metabolic approaches? I have seen sites that use ketogenic approaches with dogs and other pets and they report some reasonably good results. They often note though that these dietary changes probably should become a lifetime lifestyle feature for the animals.
It is quite striking how pets start getting human illnesses when the pets are fed like people. There are so many obese pets that are overfed with high carb diets and then go on to develop cancer etc.. People do not know how to feed themselves and then they go and feed their pets and they do not know what they are doing with their pets either. They do not realize that creating obese overfed pets is unhealthy; the pets should not be given constant snacks etc.; pets should actually be hungry sometimes. Have you ever tried 3-BP with them?
I think that you are really onto something when you talk about your aha moment. Sometimes when you simply tell someone the answer they will just right it in their notebook and give it no thought. It is only when at some level that you "discover" the answer for yourself and internalize does it feel like you own it and it is yours. I remember when I was looking at the glycolysis chart and it occurred to me in my eureka moment what if you could shut this down in cancer? That was when I searched the net about this idea and from that an article about 3-BP popped up! That what was got me started! Yet, for many other people you could try to tell them how 3-BP has merit as a cancer treatment and they would never really get it. The need to "find it" at some level for themselves.
I have also though about the Budwig approach and other metabolics and could see how they coalesce into one mega-treatment approach that largely hit the same pathways. People would often not perceive how these can all be distilled down to the label metabolic cancer therapy.
johan, you are right. Letting solutions emerge organically does make a great deal of sense, especially when we are searching for answers filled with complexity. There are so many combinations that could be tried so it would be best to let people explore as many of these as possible. However, sometimes we have discovered things like metronomic dosing that others should be made aware of, as it really did seem to help people.
Perhaps the top level ideas like metronomic dosing could be shared, while actual combos could be left more open; it would be best not to close out such options. A suggestion is that we could give a list of ideas when others run out of ideas; as we know now there is no reason to run out of ideas with cancer treatment because there are so many possibilities.
When you give animals raw food as they would eat it, combined with Budwig mix(which they tend to love) and remove the artificial food you can get very good results. I live in México, and most of the time people will rather sacrifice their pet when they see them Suffering, so when the cancer has advanced they ask my brother to put them asleep. Some people get amazed by the results and start eating the mix as well. With people I have used the Budwig mix, Lipoic acid (per os), coeq10, and citric acid what I have noticed is that as citric acid goes up, Prostate Sp. Antigen goes down... And it happens very fast, that's how I told one of my patients, at first the oncologist said there was no cure because he had bone Mets and everyone was crying... he started the citric acid and the PSA went from... i can't remember very well (40-50)..to 0.1 (after 2months with 7gr citric acid a day) and the bone gamma gram after six months was "uncertain... So the oncologist said it was good news and started him on antiandrogen medication(leuprolide, bicalutamide) .. Diffuse Inflammation but apparently no blasts" he was on Budwig Mix and Citric acid with removal of artificial sugars... I've been following him for 3 years.. He only continue with diet and Budwig mix because he couldn't tolerate the citric acid after one year... I have seen many of my patients die, I've been to their funerals and it breaks my heart when I remember the day a very loved patient of mine ask me if she should stop going to radio/chemotherapy because she was feeling awful and I told her that it was her decision... I played it safe and I knew in my heart that getting radiotherapy 2months after radical mastectomy was not a good idea that perhaps she would develop new cancer lesions around the scar... But I didn't say it I left that call to the oncologist... And a few months after she came back to me full of "new" lesions around her mastectomy scar... i felt truly bad... From there everything went bad and she developed brain Mets.. I went to her funeral and promised right there that I would do my best for the new patients to come... Alright, my heart is out
Thanks for sharing this Yud. This goes to the heart of the matter. It's not easy.
Thanks, Daniel! Your new post is a gem, this will make it a lot easier to navigate the different treatment options.
@johan
Thank you for feedback, Johan!