https://www.imrpress.com/journal/FBL/27/9/10.31083/j.fbl2709263/htm

Conclusions
Active natural compounds have anticancer properties in vitro and in vivo through different mechanisms and pathways. Natural compounds combined with conventional therapies can improve the sensitivity of conventional therapies, decrease the dosage of drugs, reduce treatment resistance, and reduce the adverse effects of conventional therapies. It has the potential to become an essential therapeutic tool for treating colorectal cancer progression and metastases.