An idea for using DCA for colon cancer
Why you think this combination would target hypoxia specifically, other than their general anti cancer effects.
Because Atovaquone is a mitochondria inhibitor while DCA "redirects" pyruvate to mito, the combo of the two should be a good idea as it should act in the same way as DCA & Metformin, shown in the lab to have an enhanced capability for killing cancer cells.
I wrote a post on DCA where I discussed dose https://www.cancertreatmentsresearch.com/dichloroacetate-dca-treatment-strategy/
And here is a good article on Atovaquone https://www.ncbi.nlm.nih.gov/pubmed/27136895
However, I have no info on correlating the two in terms of dose. I do not expect you can find such info as it is very specific and may depend on drug dynamics in each person. The best that can be done is to take a safe dose of each in combo.
Finally, thanks for your question as it brought to my attention Atovaquone as a mitochondria inhibitor.
What makes does correlation, crucial:
DCA treatment also induced significantly increased growth of SW480 tumor ...
Thanks for info