Reduce risk for relapse?
my wife was diagnosed with stage 3a CC in 2014 and was treated with Cisplatin and a maximum dose of radiation to the pelvic region + brachytherapy. Fortunately she responded very well and has to date remained in remission. She has been on a quite comprehensive protocol for the last 4-years of repurposed drugs and supplements, plus HBOT.
Needless to say we are very happy about this. My question to you is how should her protocol for lets say the next 5-years should look like to minimize the risk for relapse?
Currently she is taking:
Metformin (3x500mg); Mebendazole (1x100mg); Atorvastatin (1x40mg); Doxycycline(1x100mg perhaps three cycles of 1 month per year); Propranolol (1x40mg); Desloratadine (2x5mg); Flarin(1x200mg e2d)
Curcumin; Corioulus; Silimarin; Broccoli extract; Vit-D; Omega-3; Bio-perine; EGCg; IP6; Nattokinase.
Daniel and this site has ben invaluable during this struggle. For this I am extremely thankful!
Hi Carl and others,
My mum was diagnosed with colon cancer in October 2018 (resected, 3 rounds of 5FU (capecitabine) and oxaliplatin) along with Metabloc and Curcumin and boosters, also saponins and Reishi, Shiitake, vitamins, minerals.
Cea 0.4, 0.4, 0.8 (starting chemo), 1.2 (chemo peak), 0.7 (one week after chemo). CT scan from 14 days ago clear.
However, serious rash due to chemo - almost healed and now diarrhea - grade 1 (a month after chemo) - though getting better. We have to change diet from almost vegan to some white flour and limited dairy to manage diarrhea and decrease curcumin and ALA and HCA to 600mg/day for 2 weeks.
Now the protocol is ALA (1200mg), HCA (1200mg), Silymarin (1000mg), Boswellia (1500mg), Curcumin (1000mg) + Piperin (30mg), Reishi, Shiitake, Coriolus (1500mg), Aspirin (100mg), D3 (6000IU) + minerals, Apigenin, Tocotrienols (600mg), Saponins (3000mg), L-Carnitin (1000mg), Melatonin 20mg/day. I would like to return to Berberine - but it would probably cause additional stomach problems at the moment.
Anything critical to add?
Concerning the COC combination Metformin, Mebendazole, Atorvastatin, Doxycycline - does your wife take it continually for a long period or are there gaps? I am thinking about the same combination - hopefully in a month or two - perhaps with Fenbendazole switching with Menbendazole.
Have you suffered any side effects during the protocol?
Thank you so much for the kind words. I am very glad to know that your wife is well. You did and are doing a great job and thank you for supporting this website both with donations and comments for so long time.
You already know a lot and it's challenging to add extra value to what you already know. This is why, at this point I only have a general remark: what I would do further is to make sure that I address well the inflammation (from both a lifestyle point of view (e.g. low stress, suitable diet) and drug/supplement point of view).
A specific anti inflammatory supplement that comes to my mind as one of the best and I do not see it on your list is Olive Leaf extract. Ergin, one of the contributors and friends we had around some time ago, mentioned this one often as he saw very good results with his mom. This has been recommended to me by many and next to the anecdotes there is a good amount of science on it. On the same line, as you know, Aspirin 100mg/day is one of my preferred anti-inflammatory approach.
Ashwagandha is a good one against stress (cortisol) and inflammation.
Next to inflammation, the immune systems is an important aspect in the preventive stage. That you are already addressing well. Just that Doxycicline is the one that I would think about how to reduce and possibly replace. Or at leadt I would make sure I add a lot of good probiotics. Sauerkraut is one of the best probiotic in my view, and you can easily make it at home. Another good one is Pro Em San from a German company called Tisso.
It could make sense to start a post on prevention and we should dig deeper on this line. I will do that asap after starting the post on Glyco inhibitors in the coming weeks.
for Colorectal and Colon cancer Cimetidine would be an important one. Please search through this website the discussion on Cim using the search option at the top of the page, You will find relevant discussion including that relatde to interaction of Cim with other drugs. You will probably also want to start communication with Caio https://www.cancertreatmentsresearch.com/colon-and-colorectal-cancer/#comment-8347
Please check the points made above regarding Inflammation, which is the major aspect to address. I would address any other intervention that is not strictly required as many recurrences happens in patients after interventions such as for removal of colostomy, etc.