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25/07/2020 12:22 am
Mildronate is a drug used in some European countries for increasing oxygen to tissues to treat coronary artery disease. https://en.wikipedia.org/wiki/Meldonium
Mildronate is a gamma-butyrobetaine hydroxylase 1 (BBOX1) inhibitor, known to facilitate cell synthesis of carnitine, a molecule that plays a key role in energy metabolism.
BBOX1 inhibitors have been recently shown to kill TNBC cells.
https://www.sciencedaily.com/releases/2020/07/200722142733.htm