Hello all,
My partner has a high grade glioma on the brain stem. He was treated with radiotherapy 9 years ago with great success. Last summer the tumor came back and started chemotherapy (Temozolomide) in August.
On the follow up scans there is evidence of shrinkage and on the last one (Feb) it shows the tumor has reduced by half compared to first one in July.
This is great news as it seems that whatever we are doing is working so far. Now he will have another 3 month’s cycle of chemotherapy and if all goes well, he may have a break from it.
We started implementing COC protocol from the beginning and adding other stuff and making many mistakes along the way.
The strategies proposed by Daniel totally resonate with us and we can’t express how helpful have been and how thankful we are for all the information on the website.
Now, we are in a position deciding what to do next as to maximise the results we already had and hopefully aiming for more tumor reduction. I believe there is much more we could do and there is room for improvement in our protocol.
I’ll be very grateful if you could give us any advise.
For context this is what we are already doing:
Ketogenic diet
COC protocol (Metformin, Simvastatin and Mebendazole - haven’t started with Doxycycline yet)
Temozolomide 180mg (5 days a month)
Dexamethasone 1mg
Omeoprazol
Vitamin D
Boswellia 2.5g
Curcumine Longvida 5g
EGCG 1.400mg
Resveratrol 1g
Artemisa Annua tea
Melatonine 20mg
Honokiol liposomal (MSC formulas) - 6 capsules/day
Glutamine Inhibifour (MSC formulas) - we recently added this but not sure what the appropriate dose would be - taking 2 capsules at the moment and if it has to be stopped during chemotherapy days. Same for Honokiol.
During the chemotherapy days we stop everything two days before and on the day the chemo starts we add the COC protocol, melatonin, Honokiol and Glutamine Inhibifour - the rest of the supplements two days after finishing chemotherapy.
He is also taking in the morning the “Budwig mixture,” which flaxseed oil and that supplies about 11g Omega 3 fatty acids but in an article from Daniel it is written that flaxseed oil interferes with statins anticancer action. Should he stop the Budwig and go to Omega 3 supplementation instead?:
“Therefore, during the use of statins, patients should avoid the use of foods containing high levels of geranylgeraniol, including rice, sunflower and linseed/flaxseed oil. Actually, it has been already suggested 10 years ago, that addition of geranylgeraniol can prevent cytotoxic effects of statins and with that also limiting the toxicities of statins (Ref.), and more recently geranylgeraniol has been suggested to be useful in protecting patients against the side effects of Bisphosphonates”
As our core treatment is Chemotherapy it will make sense to use a pro-oxidative approach applied in a pulse way and perhaps an antioxidant approach in combination - in that case what off-label and supplements would be good to add? I find confusing to put together as many of the things we use already have effects in different pathways.
Was thinking of adding, either Celecoxib, Hydroxychloroquine, artemisin? Is the dose of supplements we are taking enough? should we increase dosage?
Any suggestions would be greatly appreciate it. Many thanks in advance.
Hello all,
My partner has a high grade glioma on the brain stem. He was treated with radiotherapy 9 years ago with great success. Last summer the tumor came back and started chemotherapy (Temozolomide) in August.
On the follow up scans there is evidence of shrinkage and on the last one (Feb) it shows the tumor has reduced by half compared to first one in July.
This is great news as it seems that whatever we are doing is working so far. Now he will have another 3 month’s cycle of chemotherapy and if all goes well, he may have a break from it.
We started implementing COC protocol from the beginning and adding other stuff and making many mistakes along the way.
The strategies proposed by Daniel totally resonate with us and we can’t express how helpful have been and how thankful we are for all the information on the website.
Now, we are in a position deciding what to do next as to maximise the results we already had and hopefully aiming for more tumor reduction. I believe there is much more we could do and there is room for improvement in our protocol.
I’ll be very grateful if you could give us any advise.
For context this is what we are already doing:
Ketogenic diet
COC protocol (Metformin, Simvastatin and Mebendazole - haven’t started with Doxycycline yet)
Temozolomide 180mg (5 days a month)
Dexamethasone 1mg
Omeoprazol
Vitamin D
Boswellia 2.5g
Curcumine Longvida 5g
EGCG 1.400mg
Resveratrol 1g
Artemisa Annua tea
Melatonine 20mg
Honokiol liposomal (MSC formulas) - 6 capsules/day
Glutamine Inhibifour (MSC formulas) - we recently added this but not sure what the appropriate dose would be - taking 2 capsules at the moment and if it has to be stopped during chemotherapy days. Same for Honokiol.
During the chemotherapy days we stop everything two days before and on the day the chemo starts we add the COC protocol, melatonin, Honokiol and Glutamine Inhibifour - the rest of the supplements two days after finishing chemotherapy.
He is also taking in the morning the “Budwig mixture,” which flaxseed oil and that supplies about 11g Omega 3 fatty acids but in an article from Daniel it is written that flaxseed oil interferes with statins anticancer action. Should he stop the Budwig and go to Omega 3 supplementation instead?:
“Therefore, during the use of statins, patients should avoid the use of foods containing high levels of geranylgeraniol, including rice, sunflower and linseed/flaxseed oil. Actually, it has been already suggested 10 years ago, that addition of geranylgeraniol can prevent cytotoxic effects of statins and with that also limiting the toxicities of statins (Ref.), and more recently geranylgeraniol has been suggested to be useful in protecting patients against the side effects of Bisphosphonates”
As our core treatment is Chemotherapy it will make sense to use a pro-oxidative approach applied in a pulse way and perhaps an antioxidant approach in combination - in that case what off-label and supplements would be good to add? I find confusing to put together as many of the things we use already have effects in different pathways.
Was thinking of adding, either Celecoxib, Hydroxychloroquine, artemisin? Is the dose of supplements we are taking enough? should we increase dosage?
Any suggestions would be greatly appreciate it. Many thanks in advance.
Hi, this looks good. In any case, whenever you see tumors getting smaller you definitely need to continue what you're doing. No need to start DOXY in the current situation IMO. I'd get magnolol to take with honokiol.
Good luck!
@j Thank you Johan. Why would you add Magnolol? Don't they have similar properties?
@j Thank you Johan. Why would you add Magnolol? Don't they have similar properties?
yes, I would. Check the image of the tumors of the mice here
https://synergiesforcancertreatments.blogspot.com/p/honokiol.html
Adding Magnolol really made the difference
