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Preventing chemotherapy-induced myelosuppression with Licorice?


Daniel
(@daniel)
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Joined: 6 years ago
Posts: 1053
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Today I came across this article suggesting that FLT3 inhibitors could be usefull to prevent hemotherapy-induced myelosuppression: 

Preventing chemotherapy-induced myelosuppression by repurposing the FLT3 inhibitor quizartinib https://stm.sciencemag.org/content/9/402/eaam8060?rss=1

The consequences of myelosuppression include anemia, thrombocytopenia, and neutropenia.

Isoliquiritigenin is an orally available natural FLT3 inhibitor found in Licorice, a medicinal herb widely used to treat inflammation-related diseases in china https://www.ncbi.nlm.nih.gov/pubmed/31462456

Licorice is often used in alternative cancer treatment space and the above studies suggest that taking it prior to chemo therapy may help reduce side effects of chemo such as anemia, thrombocytopenia, and neutropenia.


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