Mebendazole: A Cancer Fighting Drug We Find at the Supermarket

Background: Yes, in the European countries Mebendazole can be found on the supermarket shelves. Mebendazole is an anthelmintic drug that has been used since the early 1970s to treat a range of parasitical worm infections, including threadworm, tapeworms, roundworms, and other nematode and trematode infections in humans and domestic animals (Ref.). The drug is among those on the World
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Phosphoethanolamine & Meclizine: inhibiting an enzyme required to form the building blocks of membranes

Summary Actually, the title (inhibiting an enzyme required to form the building blocks of membranes) refers to Meclizine since as we will shortly discuss below, Phosphoethanolamine acts (probably) on mitochondria. The compound, Phosphoethanolamine, has been shown to kill tumor cells (A. K. Ferreira et al. Anticancer Res.32, 95€“104; 2012) at the University of S£o Paulo in Brazil. As a result some
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Chloroquine & Hydroxychloroquine: supporting chemo effectiveness and more

Summary Chloroquine is an anti-malarial drug available at pharmacies for people traveling to area with malaria risks. Note: based on a RGCC chemosensitivity analysis I have seen at a German clinic, Hydroxychloroquine has been effective in killing the cancer cells of 5 out 7 patients that were tested. It is one of very few available drugs
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Diflunisal

CAS 22494-42-4 My opinion: An anti-cancer treatment with great potential relevant for most types of cancers visible on PET/CT. Regarding its effectiveness, this statements says it all: “33 patients were evaluable for metric response, 20 for metabolic and 19 for tumor marker response assessment. For tumor marker follow up 11 % had a CR, 53 %
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Plerixafor (Mozobil)

My opinion: Plerixafor works against the part of immune system (M2–macrophages) that helps the tumor to regrow after an effective treatment has succeeded to kill part of it. Therefore, Plerixafor is a great supportive treatment for any effective anti cancer strategy including surgery, chemo and radiotherapy. We do not have any experience with it. Summary & Mechanism The immune system plays a major
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